公开(公告)号：US20180193131A1

公开(公告)日：2018-07-12

申请号：US15911629

申请日：2018-03-05

申请人： Endologix, Inc.

发明人： Stefan Schreck ,  Daniel Hawkins

IPC分类号： A61F2/07 ,  A61F2/856 ,  A61F2/24 ,  A61F2/06 ,  A61F2/90 ,  A61F2/89

CPC分类号： A61F2/07 ,  A61F2/2412 ,  A61F2/856 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2250/0024

摘要： Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.

公开(公告)号：US20170216022A1

公开(公告)日：2017-08-03

申请号：US15491401

申请日：2017-04-19

申请人： Massachusetts Eye and Ear Infirmary ,  The Charles Stark Draper Laboratory, Inc.

发明人： Mark E. Keegan ,  Michael J. McKenna

IPC分类号： A61F2/18 ,  A61L27/14 ,  A61L27/54

CPC分类号： A61F2/18 ,  A61F2002/183 ,  A61F2230/0004 ,  A61F2230/0069 ,  A61F2240/001 ,  A61F2250/0024 ,  A61F2250/0067 ,  A61L27/14 ,  A61L27/54 ,  A61L2300/602 ,  Y10T29/49826 ,  Y10T29/49828

摘要： A medical implant device includes a prosthesis adapted to replace at least a portion of a bone. The prosthesis includes a drug-eluting polymer adapted to deliver a drug to at least a portion of an area surrounding the prosthesis.

公开(公告)号：US09707070B2

公开(公告)日：2017-07-18

申请号：US14789574

申请日：2015-07-01

申请人： Cook Medical Technologies LLC

发明人： Shaun D. Gittard ,  Vihar C. Surti

IPC分类号： A61F2/38 ,  A61F2/00 ,  A61F2/04 ,  A61F2/844 ,  A61F2/848 ,  A61F2/90 ,  A61L31/02 ,  A61L31/04 ,  A61L31/12 ,  A61L31/14

CPC分类号： A61F2/0077 ,  A61F2/04 ,  A61F2/844 ,  A61F2/848 ,  A61F2/90 ,  A61F2002/0086 ,  A61F2002/044 ,  A61F2002/045 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2250/0024 ,  A61F2250/0025 ,  A61L31/022 ,  A61L31/04 ,  A61L31/12 ,  A61L31/14 ,  A61L31/146

摘要： A prosthesis and a method for securing a prosthesis at a treatment site are provided. The prosthesis includes a material portion. The material portion includes a liquid-impermeable material layer, a porous material layer having a pore size adapted for promoting tissue ingrowth, and an adhesive portion provided on the porous material layer adapted to secure the material portion to a site for at least 24 hours following implantation of the prosthesis at the site. In some embodiments, the prosthesis further includes a body.

公开(公告)号：US09597181B2

公开(公告)日：2017-03-21

申请号：US14976866

申请日：2015-12-21

申请人： Tendyne Holdings, Inc.

发明人： Mark Christianson ,  Chad Perrin ,  Zachary Tegels ,  Craig Ekvall ,  Robert Vidlund ,  Son Mai ,  Michael Evans

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2/2463 ,  A61F2/2487 ,  A61F2210/0014 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/001 ,  A61F2230/0034 ,  A61F2230/0093 ,  A61F2250/0018 ,  A61F2250/0023 ,  A61F2250/0024 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0069

摘要： A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets.

公开(公告)号：US09370427B2

公开(公告)日：2016-06-21

申请号：US11786831

申请日：2007-04-13

申请人： Christopher G. Sidebotham

发明人： Christopher G. Sidebotham

IPC分类号： A61F2/36 ,  A61F2/30 ,  A61L27/06 ,  A61L27/30 ,  A61L27/34 ,  B22F7/00 ,  A61F2/46 ,  B22F3/24

CPC分类号： A61F2/30907 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/367 ,  A61F2/3676 ,  A61F2002/30013 ,  A61F2002/30014 ,  A61F2002/30064 ,  A61F2002/30138 ,  A61F2002/30322 ,  A61F2002/30703 ,  A61F2002/30919 ,  A61F2002/30929 ,  A61F2002/30957 ,  A61F2002/30967 ,  A61F2002/30968 ,  A61F2002/30971 ,  A61F2002/30973 ,  A61F2002/3625 ,  A61F2002/4631 ,  A61F2230/0017 ,  A61F2250/0018 ,  A61F2250/0024 ,  A61F2250/0026 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00407 ,  A61F2310/00413 ,  A61F2310/00491 ,  A61F2310/00544 ,  A61L27/06 ,  A61L27/30 ,  A61L27/34 ,  B22F7/004 ,  B22F2003/242 ,  B22F2003/248 ,  B22F2998/10 ,  B22F2999/00 ,  C08L71/12 ,  B22F3/1112 ,  B22F3/1146 ,  B22F3/24 ,  B22F3/1266

摘要： A femoral stem for canines or humans is made bone-compliant by use of a thick sintered titanium body in a proximal bone contacting region and a polymeric or ceramic body in a distal bone contacting region of the femoral stem. An elastic modulus is thereby engineered to match that of bone tissue. The porous sintered titanium body is created by sintering spheres of titanium. It is bonded to a central solid biocompatible metallic body by diffusion bonding. The distal region has a biocompatible polymeric body or biocompatible cement body. When compression molded the distal region develops an elastic modulus matching that of bone tissue. The proximal region has a porosity designed to encourage bone ingrowth.

摘要翻译： 用于犬或人的股骨柄通过使用近端骨接触区域中的厚的烧结钛体和在股骨柄的远端骨接触区域中的聚合体或陶瓷体而被制成骨相容性。 因此，设计弹性模量以匹配骨组织的弹性模量。 多孔烧结钛体是通过烧结钛的球体而产生的。 通过扩散粘合将其结合到中心固体生物相容性金属体上。 远侧区域具有生物相容的聚合体或生物相容的水泥体。 当压缩模制时，远侧区域产生与骨组织匹配的弹性模量。 近端区域具有旨在促进骨向内生长的孔隙。

公开(公告)号：US20160158011A1

公开(公告)日：2016-06-09

申请号：US14656006

申请日：2015-03-12

申请人： Didier de Canniere

发明人： Didier de Canniere

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2448 ,  A61F2/2454 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2230/0069 ,  A61F2240/002 ,  A61F2250/0024

摘要： A device structured to suppress mitral regurgitation by restricting prolapse of a mitral valve leaflet and including a base correspondingly dimensioned to the mitral valve and including a central portion, structured to allow blood flow there through and a peripheral portion or ring connected to the central portion in substantially surrounding relation thereto. An operative position of the base includes the central portion disposed in overlying, movement restricting relation to at least one of the valve leaflets and the ring concurrently anchored adjacent or directly to the native annulus of the mitral valve. The physical characteristics of the base facilitate its movement with and conformance to the mitral valve during diastole and systole cycles of the heart.

摘要翻译： 一种被构造成通过限制二尖瓣小叶脱垂并且包括相应地尺寸设定到二尖瓣的基部并包括中心部分的装置，该中心部分被构造成允许血液流过其中，并且连接到中心部分的周边部分或环 基本上围绕其关系。 基座的操作位置包括中心部分，该中心部分以与二尖瓣的天然环状物相邻或直接地同时锚定的至少一个瓣叶片和环的上部移动限制关系设置。 基部的物理特性有助于其在舒张期和心脏收缩期间与二尖瓣的运动并符合二尖瓣。

公开(公告)号：US09333070B2

公开(公告)日：2016-05-10

申请号：US14042457

申请日：2013-09-30

申请人： Evera Medical, Inc.

发明人： Randy J. Kesten ,  Michael D. Lesh

IPC分类号： A61F2/12 ,  A61F2/00 ,  A61F2/52

CPC分类号： A61F2/12 ,  A61F2/0059 ,  A61F2/0077 ,  A61F2/52 ,  A61F2230/0034 ,  A61F2230/0093 ,  A61F2250/0003 ,  A61F2250/0009 ,  A61F2250/001 ,  A61F2250/0012 ,  A61F2250/0013 ,  A61F2250/0015 ,  A61F2250/0024 ,  A61F2250/0025 ,  A61F2250/0028 ,  A61F2250/0051

摘要： An implantable prosthesis is provided having a membrane which holds a flowable substance. The membrane is separated into a first chamber and a second chamber with the first and second chambers being fluidly coupled via an orifice. The orifice has a size which may be adjusted by the user after implanting the prosthesis into the patient.

摘要翻译： 提供具有保持可流动物质的膜的可植入假体。 膜被分离成第一室和第二室，其中第一和第二室通过孔流体耦合。 孔口具有在将假体植入病人之后可由使用者调节的尺寸。

公开(公告)号：US20160058616A1

公开(公告)日：2016-03-03

申请号：US14826866

申请日：2015-08-14

申请人： CAMRAS VISION INC.

发明人： Lucinda Camras ,  Rolf Erik Ypma

IPC分类号： A61F9/007

CPC分类号： A61F9/00781 ,  A61F2250/0024

摘要： An apparatus for reducing/stabilizing intraocular pressure is provided. A tube extends from an inlet end in fluid communication with an anterior chamber of the eye, to direct an aqueous humor flow from the anterior chamber to an outlet end in fluid communication with a cavity, defined by a housing, for receiving the aqueous humor. A flow control device is operably engaged with the housing, and is configured to control the flow of the aqueous humor, via a conduit defined thereby and extending from the cavity, to a location away from the anterior chamber. The conduit is dilatable in response to the intraocular pressure being above a preselected pressure, to increase the flow or to decrease resistance to flow of the aqueous humor through the conduit to the drainage site and to reduce the intraocular pressure to no greater than the preselected pressure. Associated apparatuses and methods are also provided.

摘要翻译： 提供了一种用于降低/稳定眼内压的装置。 管从与眼睛的前房流体连通的入口端延伸，以将房水从前房流引导到出口端，其与由壳体限定的用于接收房水的空腔流体连通。 流量控制装置与壳体可操作地接合，并且被配置成通过由其限定并从腔延伸到远离前房的位置来控制房水的流动。 导管响应于眼压高于预选压力而可扩张，以增加流量或降低房水通过导管流到排水部位的阻力，并将眼内压降低至不超过预选压力 。 还提供了相关的装置和方法。

公开(公告)号：US20160058615A1

公开(公告)日：2016-03-03

申请号：US14473228

申请日：2014-08-29

申请人： CAMRAS VISION INC.

发明人： LUCINDA J. CAMRAS ,  RAND ALLINGHAM ,  BRUCE KLITZMAN ,  SANJAY ASRANI

IPC分类号： A61F9/007

CPC分类号： A61F9/00781 ,  A61F2250/0024 ,  A61F2250/0051

摘要： An apparatus is provided for draining aqueous humor from an eye for reducing intraocular pressure. The draining apparatus comprises a tube defining a passage for fluid flow between an inlet end and an outlet end. An outlet assembly contacts the conjunctival layer externally of the eyeball. The outlet assembly comprises a housing in fluid communication with the outlet end of the tube and having an aperture for allowing egress of aqueous humor onto the external ocular surface. A resistive component is disposed in the housing for providing resistance to a flow of aqueous humor. A pair of tabs project outwardly and are adapted to be disposed subconjunctivally for securing the draining apparatus relative to the eyeball.

摘要翻译： 提供了用于从眼睛排出房水以降低眼内压的装置。 排水装置包括限定用于在入口端和出口端之间流体流动的通道的管。 出口组件与眼球外部的结膜层接触。 出口组件包括与管的出口端流体连通的壳体，并且具有用于允许房水流出到外眼表面上的孔。 电阻部件设置在壳体中以提供对房水流的阻力。 一对翼片向外突出并适于被并联设置，用于相对于眼球固定排水装置。

公开(公告)号：US09220829B2

公开(公告)日：2015-12-29

申请号：US13044147

申请日：2011-03-09

申请人： Zvi Herschman

发明人： Zvi Herschman

IPC分类号： A61F2/04 ,  B01D61/42 ,  A61M1/16 ,  A61F2/02 ,  A61M1/34 ,  B01D61/46 ,  B01D61/44 ,  B01D61/52 ,  B01D61/54 ,  B01D57/02

CPC分类号： A61F2/022 ,  A61F2230/0069 ,  A61F2250/0001 ,  A61F2250/0023 ,  A61F2250/0024 ,  A61F2250/0043 ,  A61M1/1678 ,  A61M1/3417 ,  B01D57/02 ,  B01D61/42 ,  B01D61/422 ,  B01D61/425 ,  B01D61/44 ,  B01D61/46 ,  B01D61/52 ,  B01D61/54

摘要： Systems and methods utilize semipermeable nanotubes in conjunction with application of controlled electrical potentials across semipermeable nanotube walls allow selective transport of charged impurities (e.g., charged impurities, ions, etc.) from a fluid into these nanotubes. Impurities collected in these nanotubes can then be removed from the fluid, (e.g., blood) as a waste stream. A collection of semipermeable nanotubes each carrying a waste stream can be aggregated and merged into a ureter for excretion thereby providing an artificial kidney system. Sensors that detect/measure various impurities may be included in the system to feed information to a microprocessor to inform on concentrations of impurities, and thereby control electrical potentials applied to the system.

摘要翻译： 系统和方法利用半透性纳米管与半透性纳米管壁上的受控电位的应用相结合，允许从流体选择性地将带电杂质（例如带电杂质，离子等）输送到这些纳米管中。 然后可以将这些纳米管中收集的杂质作为废物流从流体（例如血液）中除去。 每个携带废物流的半透明纳米管的集合可以聚集并合并到输尿管中用于排泄，从而提供人造肾系统。 检测/测量各种杂质的传感器可以包括在系统中以将信息馈送到微处理器以通知杂质的浓度，从而控制施加到系统的电位。