-
公开(公告)号:US10753913B2
公开(公告)日:2020-08-25
申请号:US15194982
申请日:2016-06-28
申请人: Andrew Tipler
发明人: Andrew Tipler
摘要: Certain configurations of a gas chromatography system comprising an internal gas generator are described. In some instances, the gas chromatography system may comprise an internal hydrogen generator to provide hydrogen gas to a chromatography column for separation of analyte species. In certain examples, the gas chromatography system can be operated without any external gas inputs.
-
公开(公告)号:US20160161452A1
公开(公告)日:2016-06-09
申请号:US14058329
申请日:2013-10-21
申请人: Andrew Tipler
发明人: Andrew Tipler
IPC分类号: G01N30/40
CPC分类号: G01N30/40 , G01N30/32 , G01N30/463 , G01N30/465 , G01N30/468 , G01N30/6095 , G01N2030/402 , G01N2030/445 , Y10T137/0318 , Y10T137/0396 , Y10T137/877
摘要: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device and that implement one or more methods to direct sample to a desired fluid flow path. The methods can be used to backflush a sample to a desired fluid flow path to select certain analytes within a sample.
摘要翻译: 本文描述的某些实施例涉及包括微流体装置并且实施一种或多种方法以将样品引导至期望的流体流动路径的色谱系统。 这些方法可用于将样品反吹到所需的流体流动路径以选择样品中的某些分析物。
-
公开(公告)号:US20130000485A1
公开(公告)日:2013-01-03
申请号:US13172263
申请日:2011-06-29
申请人: Andrew Tipler , Greg Johnson , David J. Scott
发明人: Andrew Tipler , Greg Johnson , David J. Scott
IPC分类号: B01D53/04
CPC分类号: G01N30/08 , G01N30/12 , G01N30/38 , G01N2030/085 , G01N2030/128 , G01N2030/385
摘要: A flow control system, method and device for performing thermal desorption is provided. In one embodiment, the system includes a first flow path in which gas flows from a first carrier gas inlet, through a first vessel in a first direction at a first flow rate to adsorb analytes on an adsorbent of said first vessel; a second flow path in which gas flows from a second carrier gas inlet, through said first vessel in the first direction at a second flow rate to further adsorb the analytes on the adsorbent of said first vessel; a third flow path in which a carrier gas flows through said first vessel in a second direction to carry desorbed analytes out of said first vessel; and wherein the second flow rate of carrier gas through said first vessel is greater than the first flow rate of carrier gas through said first vessel.
摘要翻译: 提供了一种用于进行热解吸的流量控制系统,方法和装置。 在一个实施例中,系统包括第一流动路径,气体从第一载气入口以第一流量沿第一方向流过第一容器,以将分析物吸附在所述第一容器的吸附剂上; 第二流路,其中气体从第二载气入口流过所述第一容器,以第二流量在第一方向上,以进一步将分析物吸附在所述第一容器的吸附剂上; 第三流动路径,其中载气在第二方向上流过所述第一容器,以将解吸附的分析物运送出所述第一容器; 并且其中通过所述第一容器的载气的第二流量大于通过所述第一容器的载气的第一流量。
-
公开(公告)号:US20120118049A1
公开(公告)日:2012-05-17
申请号:US13158953
申请日:2011-06-13
申请人: Andrew Tipler
发明人: Andrew Tipler
IPC分类号: G01N30/00
CPC分类号: B01D53/0446 , G01N30/463 , G01N30/465 , G01N30/6095 , G01N30/62 , G01N30/72 , G01N2030/328 , Y10T137/877
摘要: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device configured to provide three-way switching or switching between three or more inputs or outputs. The microfluidic device can be fluidically coupled to one or more switching valves to provide for selective control of fluid flow in the chromatography system.
摘要翻译: 本文描述的某些实施例涉及包括配置成在三个或更多个输入或输出之间提供三路切换或切换的微流体装置的色谱系统。 微流体装置可以流体耦合到一个或多个切换阀,以提供色谱系统中流体流动的选择性控制。
-
公开(公告)号:US08104326B2
公开(公告)日:2012-01-31
申请号:US11841054
申请日:2007-08-20
申请人: Andrew Tipler , James Botelho , Avinash Dalmia , Michael J. Rafa , John Vanderhoef , Paul Schallis , Neal Green , David J. Scott , John McCaffrey , Paul St. Cyr , E. Joel McCorkle , Guiseppe Coppola
发明人: Andrew Tipler , James Botelho , Avinash Dalmia , Michael J. Rafa , John Vanderhoef , Paul Schallis , Neal Green , David J. Scott , John McCaffrey , Paul St. Cyr , E. Joel McCorkle , Guiseppe Coppola
IPC分类号: G01N30/04
CPC分类号: G01N30/30 , G01N2030/3076 , G01N2030/3084
摘要: A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.
摘要翻译: 公开了一种气相色谱系统,其包括样品引入装置,耦合到样品引入装置的烘箱和耦合到烘箱的检测器。 在某些实例中,烘箱可以被配置成在烘箱的空间中接收色谱柱。 在一些实例中,烘箱可以被构造和布置成在气相色谱系统的分析阶段期间向空间提供基本恒定的温度。
-
公开(公告)号:US07422625B2
公开(公告)日:2008-09-09
申请号:US11852655
申请日:2007-09-10
申请人: Andrew Tipler , Neil T. Plant
发明人: Andrew Tipler , Neil T. Plant
IPC分类号: B01D53/02
CPC分类号: G01N30/89 , G01N15/0826 , G01N30/32 , G01N30/60 , G01N2030/324 , G01N2030/524 , G01N2030/626 , G01N2030/525
摘要: Disclosed are systems and methods that include providing a vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a unit flow per unit pressure based on a ratio of the flow rate and the differential pressure. In certain embodiments, the flow rate at the outlet is established by controlling the flow rate of the gas. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
摘要翻译: 所公开的系统和方法包括提供具有入口和出口的容器,用于使载气通过该容器; 确定出口处的已知流速的入口和出口之间的压差; 并且基于流量和压差的比率确定单位压力的单位流量。 在某些实施例中,通过控制气体的流量来建立出口处的流量。 在一些实施方案中,方法和系统可以包括该比例的粘度,使用基于在输出处的气体压力与环境压力的比率的因子确定环境压力下的流速,和/或确定 使用基于输出温度和环境温度的比率的因子的环境温度。
-
公开(公告)号:US20080105033A1
公开(公告)日:2008-05-08
申请号:US11841054
申请日:2007-08-20
申请人: Andrew Tipler , James Botelho , Avinash Dalmia , Michael Rafa , John Vanderhoef , Paul Schallis , Neal Green , David Scott , John McCaffrey , Paul St. Cyr , E. McCorkle , Guiseppe Coppola
发明人: Andrew Tipler , James Botelho , Avinash Dalmia , Michael Rafa , John Vanderhoef , Paul Schallis , Neal Green , David Scott , John McCaffrey , Paul St. Cyr , E. McCorkle , Guiseppe Coppola
IPC分类号: G01N30/04
CPC分类号: G01N30/30 , G01N2030/3076 , G01N2030/3084
摘要: A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.
摘要翻译: 公开了一种气相色谱系统,其包括样品引入装置,耦合到样品引入装置的烘箱和耦合到烘箱的检测器。 在某些实例中,烘箱可以被配置成在烘箱的空间中接收色谱柱。 在一些实例中,烘箱可以被构造和布置成在气相色谱系统的分析阶段期间向空间提供基本恒定的温度。
-
公开(公告)号:US07267709B2
公开(公告)日:2007-09-11
申请号:US11559760
申请日:2006-11-14
申请人: Andrew Tipler , Neil T. Plant
发明人: Andrew Tipler , Neil T. Plant
IPC分类号: B01D53/02
CPC分类号: G01N30/89 , G01N15/0826 , G01N30/32 , G01N30/60 , G01N2030/324 , G01N2030/524 , G01N2030/626 , G01N2030/525
摘要: Disclosed are systems and methods that include providing a vessel having an adsorbent disposed therein, the vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a geometric measure for the vessel based on a ratio of the known flow rate and the differential pressure. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
摘要翻译: 公开了包括提供其中设置有吸附剂的容器的系统和方法,所述容器具有用于使载气通过容器连通的入口和出口; 确定出口处的已知流速的入口和出口之间的压差; 并且基于已知流量和压差的比率确定容器的几何度量。 在一些实施方案中,方法和系统可以包括该比例的粘度,使用基于输出处的气体压力和环境压力的比率的因子确定环境压力下的流速,和/或确定 使用基于输出温度和环境温度的比率的因子的环境温度。
-
公开(公告)号:US20060263901A1
公开(公告)日:2006-11-23
申请号:US11403527
申请日:2006-04-13
申请人: Andrew Tipler , Christopher Mazza , David Scott
发明人: Andrew Tipler , Christopher Mazza , David Scott
IPC分类号: G01N1/00
CPC分类号: G01N30/12 , G01N1/2226 , G01N1/405 , G01N30/24 , G01N2001/2229 , G01N2030/025 , G01N2030/121 , G01N2030/202 , G01N2030/626 , Y10T436/117497 , Y10T436/17 , Y10T436/25 , Y10T436/25875
摘要: A method for introducing standard gas into a sample vessel is generally disclosed comprising providing a vessel containing a sample gas and a receptacle with a vessel port, such as sampling needle, pressurizing the vessel with a carrier gas, and introducing a volume of standard gas into the flow path of the carrier gas being used to pressurize the vessel when the vessel port of the receptacle is located within the vessel. In some embodiments, a rotary valve is loaded with the standard gas, and the valve is brought into fluid communication with the flow path of the carrier gas when the vessel port is within the vessel.
摘要翻译: 通常公开了将标准气体引入样品容器的方法,该方法包括提供容纳样品气体的容器和具有容器端口的容器,例如采样针,用载气对容器加压,并将一定体积的标准气体引入 当容器的容器端口位于容器内时,载气的流动路径用于对容器加压。 在一些实施例中,旋转阀装载有标准气体,并且当容器端口在容器内时阀与载气的流动路径流体连通。
-
公开(公告)号:US07111494B2
公开(公告)日:2006-09-26
申请号:US11072829
申请日:2005-03-04
申请人: Andrew Tipler
发明人: Andrew Tipler
IPC分类号: G01N30/02
CPC分类号: G01N30/89 , G01N15/0826 , G01N30/32 , G01N30/60 , G01N2030/324 , G01N2030/524 , G01N2030/626 , G01N2030/525
摘要: Disclosed are systems and methods that include providing a vessel having an adsorbent disposed therein, the vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determining a geometric measure for the vessel based on a ratio of the known flow rate and the differential pressure. In some embodiments, the methods and systems can include a viscosity in the ratio, determining a flow rate at ambient pressure using a factor based on a ratio of a gas pressure at the output and ambient pressure, and/or, determining a flow rate at ambient temperature using a factor based on a ratio of a temperature at the output and ambient temperature.
摘要翻译: 公开了包括提供其中设置有吸附剂的容器的系统和方法,所述容器具有用于使载气通过容器连通的入口和出口; 确定出口处的已知流速的入口和出口之间的压差; 并且基于已知流量和压差的比率确定容器的几何度量。 在一些实施方案中,方法和系统可以包括该比例的粘度,使用基于输出处的气体压力和环境压力的比率的因子确定环境压力下的流速,和/或确定 使用基于输出温度和环境温度的比率的因子的环境温度。
-
-
-
-
-
-
-
-
-