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公开(公告)号：US09192388B2
公开(公告)日：2015-11-24
申请号：US13473832
申请日：2012-05-17
申请人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Victoria Schuman , Xiaoling Zhao
发明人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Victoria Schuman , Xiaoling Zhao
CPC分类号： A61B17/1214 , A61B17/12118 , A61F2/852 , A61F2/856 , A61F2/954 , A61F2002/823 , A61F2002/826 , A61F2230/005 , A61F2230/0067 , A61F2230/0097 , A61F2250/0023
摘要： A vascular remodeling device and methods for its use are provided. The device can be positionable at a junction of a bifurcation having an aneurysm and that defines afferent and efferent vessels. Ends of the device can be at least partially inserted into the aneurysm or can anchor the device by being at least partially inserted into efferent vessels. The device can act as a scaffolding to inhibit dislodging of objects out of the aneurysm. The device can permit perfusion to the efferent vessels. Embolic material can be inserted in the aneurysm before, during, and/or after positioning the device.
摘要翻译： 提供血管重塑装置及其使用方法。 该装置可以定位在具有动脉瘤的分叉的交界处并且定义传入和传出血管。 装置的端部可以至少部分地插入动脉瘤中，或者可以通过至少部分地插入到传出血管中来锚定装置。 该装置可以作为脚手架来抑制物体从动脉瘤的移动。 该装置可以允许对输出血管灌注。 栓塞材料可以在设备定位之前，期间和/或之后插入动脉瘤中。
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公开(公告)号：US20120296361A1
公开(公告)日：2012-11-22
申请号：US13473832
申请日：2012-05-17
申请人： Anh CAM , Michael Louis Losordo , Jianlu Ma , Victoria Schuman , Xiaoling Zhao
发明人： Anh CAM , Michael Louis Losordo , Jianlu Ma , Victoria Schuman , Xiaoling Zhao
CPC分类号： A61B17/1214 , A61B17/12118 , A61F2/852 , A61F2/856 , A61F2/954 , A61F2002/823 , A61F2002/826 , A61F2230/005 , A61F2230/0067 , A61F2230/0097 , A61F2250/0023
摘要： A vascular remodeling device and methods for its use are provided. The device can be positionable at a junction of a bifurcation having an aneurysm and that defines afferent and efferent vessels. Ends of the device can be at least partially inserted into the aneurysm or can anchor the device by being at least partially inserted into efferent vessels. The device can act as a scaffolding to inhibit dislodging of objects out of the aneurysm. The device can permit perfusion to the efferent vessels. Embolic material can be inserted in the aneurysm before, during, and/or after positioning the device.
摘要翻译： 提供血管重塑装置及其使用方法。 该装置可以定位在具有动脉瘤的分叉的交界处并且定义传入和传出血管。 装置的端部可以至少部分地插入动脉瘤中，或者可以通过至少部分地插入到传出血管中来锚定装置。 该装置可以作为脚手架来抑制物体从动脉瘤的移动。 该装置可以允许对输出血管灌注。 栓塞材料可以在设备定位之前，期间和/或之后插入动脉瘤中。
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公开(公告)号：US20120296362A1
公开(公告)日：2012-11-22
申请号：US13473840
申请日：2012-05-17
申请人： Anh CAM , Michael Louis Losordo , Jianlu Ma , Sanjay Shrivastava , Xiaoling Zhao
发明人： Anh CAM , Michael Louis Losordo , Jianlu Ma , Sanjay Shrivastava , Xiaoling Zhao
IPC分类号： A61M29/00
CPC分类号： A61F2/915 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61B2017/00867 , A61B2017/12054 , A61B2017/12063 , A61F2002/823 , A61F2002/91558 , A61F2002/91583 , A61F2230/0054 , A61F2250/0054 , A61F2250/0071
摘要： A vascular remodeling device is provided that can comprise a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in the afferent vessel of a bifurcation. The distal section can comprise at least one embolization coil that can be positioned within an aneurysm to treat the aneurysm and expand from the compressed delivery state to an expanded state upon deployment. The intermediate section can allow perfusion to efferent vessels. Before, during, and/or after the device is positioned, additional embolic material can be used to treat the aneurysm.
摘要翻译： 提供血管重塑装置，其可以包括近端部分，中间部分和远端部分。 在展开期间，近端部分可以从压缩输送状态膨胀到膨胀状态，并将装置锚定在分叉的传入容器中。 远端部分可以包括至少一个栓塞线圈，该栓塞线圈可以定位在动脉瘤内以在部署时治疗动脉瘤并从压缩递送状态扩展到扩张状态。 中间部分可以允许输出血管。 在设备定位之前，期间和/或之后，可以使用额外的栓塞材料来治疗动脉瘤。
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公开(公告)号：US09351859B2
公开(公告)日：2016-05-31
申请号：US13312887
申请日：2011-12-06
申请人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
发明人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
CPC分类号： A61F2/90 , A61B17/12118 , A61B17/1214 , A61B17/12145 , A61B17/12168 , A61B17/12172 , A61B2017/00867 , A61B2017/1209 , A61F2/95 , A61F2/966 , A61F2002/823 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/0054 , A61F2230/0069 , A61F2230/0093
摘要： Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.
摘要翻译： 本文描述了包括近端部分，中间部分和远侧部分的血管重塑装置。 在展开期间，近端部分可以从压缩输送状态膨胀到膨胀状态，并将装置固定在分叉的传入容器中。 远端部分从压缩输送状态膨胀到膨胀状态，其可以是基本上平面的，大致半球形的，伞形的或逆向伞形的。 远端部分位于动脉瘤颈部或动脉瘤内的分叉交叉处。 中间部分允许灌注输出血管。 在装置就位之前或之后，栓塞材料可用于治疗动脉瘤。 远端部分可以用作支架以防止栓塞物质的突出。 该装置可用于具有整体远端栓塞保护的凝块回缩。
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公开(公告)号：US08956399B2
公开(公告)日：2015-02-17
申请号：US13469214
申请日：2012-05-11
申请人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Xiaoling Zhao
发明人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Xiaoling Zhao
CPC分类号： A61B17/12118 , A61B17/12031 , A61B17/1214 , A61B17/12172 , A61F2/07 , A61F2/844 , A61F2/86 , A61F2/90 , A61F2/915 , A61F2/95 , A61F2/954 , A61F2/966 , A61F2002/077 , A61F2002/821 , A61F2002/823 , A61F2230/0076 , A61F2240/001 , A61F2250/0039 , Y10T29/4998
摘要： Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm.
摘要翻译： 这里描述的是可以符合神经血管系统血管形状的柔性可植入装置或支架。 在一些实施例中，装置可引导血管内的血流远离动脉瘤或限制血液流动到动脉瘤。 在一些实施方案中，血管重建装置包括第一部分和突出部分。 在部署期间，设备将从压缩配置扩展到扩展配置。 第一部分将装置固定在传入血管和/或分叉的输出容器中，并且突出部分位于具有动脉瘤并且跨越动脉瘤颈部或至少部分在动脉瘤内的分叉的交界处。
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公开(公告)号：US08915950B2
公开(公告)日：2014-12-23
申请号：US13312889
申请日：2011-12-06
申请人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
发明人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
CPC分类号： A61F2/90 , A61B17/12118 , A61B17/1214 , A61B17/12145 , A61B17/12168 , A61B17/12172 , A61B2017/00867 , A61B2017/1209 , A61F2/95 , A61F2/966 , A61F2002/823 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/0054 , A61F2230/0069 , A61F2230/0093
摘要： Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.
摘要翻译： 本文描述了包括近端部分，中间部分和远侧部分的血管重塑装置。 在展开期间，近端部分可以从压缩输送状态膨胀到膨胀状态，并将装置固定在分叉的传入容器中。 远端部分从压缩输送状态膨胀到膨胀状态，其可以是基本上平面的，大致半球形的，伞形的或逆向伞形的。 远端部分位于动脉瘤颈部或动脉瘤内的分叉交叉处。 中间部分允许灌注输出血管。 在装置就位之前或之后，栓塞材料可用于治疗动脉瘤。 远端部分可以用作支架以防止栓塞物质的突出。 该装置可用于具有整体远端栓塞保护的凝块回缩。
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公开(公告)号：US20120290067A1
公开(公告)日：2012-11-15
申请号：US13469214
申请日：2012-05-11
申请人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Xiaoling Zhao
发明人： Anh Cam , Michael Louis Losordo , Jianlu Ma , Xiaoling Zhao
CPC分类号： A61B17/12118 , A61B17/12031 , A61B17/1214 , A61B17/12172 , A61F2/07 , A61F2/844 , A61F2/86 , A61F2/90 , A61F2/915 , A61F2/95 , A61F2/954 , A61F2/966 , A61F2002/077 , A61F2002/821 , A61F2002/823 , A61F2230/0076 , A61F2240/001 , A61F2250/0039 , Y10T29/4998
摘要： Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm.
摘要翻译： 这里描述的是可以符合神经血管系统血管形状的柔性可植入装置或支架。 在一些实施例中，装置可引导血管内的血流远离动脉瘤或限制血液流动到动脉瘤。 在一些实施方案中，血管重建装置包括第一部分和突出部分。 在部署期间，设备将从压缩配置扩展到扩展配置。 第一部分将装置固定在传入血管和/或分叉的输出容器中，并且突出部分位于具有动脉瘤并且跨越动脉瘤颈部或至少部分在动脉瘤内的分叉的交界处。
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公开(公告)号：US20120245671A1
公开(公告)日：2012-09-27
申请号：US13428822
申请日：2012-03-23
CPC分类号： A61F2/915 , A61B17/12031 , A61B17/12118 , A61B17/1214 , A61F2/848 , A61F2/92 , A61F2/95 , A61F2002/823 , A61F2002/9155 , A61F2002/91575 , A61F2002/9505 , A61F2002/9511 , A61F2002/9528 , A61F2002/9534 , A61F2230/0054 , A61F2250/0036
摘要： A medical device is provided. The medical device includes a vessel-engaging member attached to a distal end of a delivery wire via a connection mechanism. The vessel-engaging member includes a plurality of rows and a plurality of bridges positioned between each adjacent row, each of the bridges connecting a vertex of a first row with a corresponding vertex of a second row. The vessel-engaging member further includes first and second tapered sections coupled to the connection mechanism, each of the tapered sections projecting from a proximal row and tapering in a direction from the proximal row toward the connection mechanism, each of the tapered sections having a length measured along a longitudinal axis, wherein the length of the first tapered section is less than the length of the second tapered section.
摘要翻译： 提供医疗设备。 医疗装置包括通过连接机构附接到输送线的远端的容器接合构件。 容器接合构件包括多个行和位于每个相邻行之间的多个桥，每个桥将第一行的顶点与第二行的对应顶点相连接。 容器接合构件还包括联接到连接机构的第一和第二锥形部分，每个锥形部分从近侧排突出，并且在从近侧列朝向连接机构的方向上逐渐变细，每个锥形部分具有长度 沿着纵向轴线测量，其中第一锥形部分的长度小于第二锥形部分的长度。
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公开(公告)号：US09028540B2
公开(公告)日：2015-05-12
申请号：US13428822
申请日：2012-03-23
CPC分类号： A61F2/915 , A61B17/12031 , A61B17/12118 , A61B17/1214 , A61F2/848 , A61F2/92 , A61F2/95 , A61F2002/823 , A61F2002/9155 , A61F2002/91575 , A61F2002/9505 , A61F2002/9511 , A61F2002/9528 , A61F2002/9534 , A61F2230/0054 , A61F2250/0036
摘要： A medical device is provided. The medical device includes a vessel-engaging member attached to a distal end of a delivery wire via a connection mechanism. The vessel-engaging member includes a plurality of rows and a plurality of bridges positioned between each adjacent row, each of the bridges connecting a vertex of a first row with a corresponding vertex of a second row. The vessel-engaging member further includes first and second tapered sections coupled to the connection mechanism, each of the tapered sections projecting from a proximal row and tapering in a direction from the proximal row toward the connection mechanism, each of the tapered sections having a length measured along a longitudinal axis, wherein the length of the first tapered section is less than the length of the second tapered section.
摘要翻译： 提供医疗设备。 医疗装置包括通过连接机构附接到输送线的远端的容器接合构件。 容器接合构件包括多个行和位于每个相邻行之间的多个桥，每个桥将第一行的顶点与第二行的对应顶点相连接。 容器接合构件还包括联接到连接机构的第一和第二锥形部分，每个锥形部分从近侧排突出，并且在从近侧列朝向连接机构的方向上逐渐变细，每个锥形部分具有长度 沿着纵向轴线测量，其中第一锥形部分的长度小于第二锥形部分的长度。
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公开(公告)号：US09254205B2
公开(公告)日：2016-02-09
申请号：US13628288
申请日：2012-09-27
CPC分类号： A61F2/962 , A61B17/12118 , A61B17/1214 , A61F2/86 , A61F2/915 , A61F2002/823 , A61F2002/91533 , A61F2002/91558 , A61F2002/9505 , A61F2002/9534 , A61F2230/0054 , A61F2250/0071 , A61F2250/0098
摘要： A medical device is provided that includes a vessel-engaging member attached to a distal end of a delivery wire. The vessel-engaging member includes a plurality of rows, with each row having a plurality of struts arranged in an alternating pattern such that for each row, a first set of vertices is positioned on a proximal side, and a second set of vertices is positioned on a distal side. The vessel-engaging member further includes a plurality of single bridges positioned between adjacent rows, each of the bridges connecting a vertex of a first row with a corresponding vertex of an adjacent second row. The vessel-engaging member can also include a plurality of double bridges positioned between adjacent rows, each of the double bridges connecting a vertex of a first row with two adjacent vertices of an adjacent second row.
摘要翻译： 提供了一种医疗装置，其包括附接到输送线的远端的容器接合构件。 容器接合构件包括多行，每排具有以交替图案布置的多个支柱，使得对于每一行，第一组顶点位于近侧，并且第二组顶点被定位 在远端 容器接合构件还包括位于相邻行之间的多个单个桥，每个桥将第一行的顶点与相邻的第二行的相应顶点相连接。 容器接合构件还可以包括位于相邻行之间的多个双桥，每个双桥将第一行的顶点与相邻的第二行的两个相邻顶点相连接。
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