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    Pressure sensor and method of fabricating such a module
    1.
    发明授权
    Pressure sensor and method of fabricating such a module 有权
    压力传感器及其制造方法

    公开(公告)号：US07418868B1

    公开(公告)日：2008-09-02

    申请号：US11359952

    申请日：2006-02-21

    申请人： Annapurna Karicherla ,  Sheldon Williams ,  Gene A. Bornzin ,  John W. Poore ,  Dion F. Davis

    发明人： Annapurna Karicherla ,  Sheldon Williams ,  Gene A. Bornzin ,  John W. Poore ,  Dion F. Davis

    IPC分类号： G01L7/00

    CPC分类号： G01L19/142 ,  G01L19/0046 ,  G01L19/0061 ,  G01L19/0645

    摘要： A body fluid pressure sensor module according to the invention comprises a housing having a first end and a second end and enclosing a pressure sensor. The pressure sensor is electrically coupled to a plurality of electrical conductors extending into the housing through a feedthrough disposed within, and hermetically sealing, the first end of the housing. The housing defines a chamber disposed between the feedthrough and the second end of the housing. The chamber contains a material in communication with the pressure sensor, the material being capable of transmitting pressure variations to the pressure sensor. The plurality of electrical conductors have ends within the housing, and the pressure sensor is mounted on the end of at least one of the conductors. Also disclosed are medical leads incorporating the pressure sensor module, and methods for fabricating the modules. The pressure sensor module is compact, and particularly so where cable conductors are utilized and the sensor is directly mounted on at least one of the cable conductors. The compactness of a pressure sensor module pursuant to the invention facilitates its incorporation into a small diameter, flexible medical lead enhancing its placement within a patient's body, for example, within the left atrium of the heart.

    摘要翻译： 根据本发明的体液压力传感器模块包括具有第一端和第二端并且包围压力传感器的壳体。 压力传感器电耦合到通过设置在壳体的第一端内并且密封地密封壳体中的馈通部延伸到壳体中的多个电导体。 壳体限定设置在馈通和壳体的第二端之间的室。 该室包含与压力传感器连通的材料，该材料能够将压力变化传递到压力传感器。 多个电导体具有在壳体内的端部，并且压力传感器安装在至少一个导体的端部上。 还公开了结合压力传感器模块的医疗引线以及用于制造模块的方法。 压力传感器模块是紧凑的，特别是在使用电缆导体并且传感器直接安装在至少一个电缆导体上的情况下。 根据本发明的压力传感器模块的紧凑性便于其结合到小直径的柔性医疗引线中，从而增强其在患者身体内的放置，例如在心脏的左心房内。

    BIOELECTRIC BATTERY FOR IMPLANTABLE DEVICE APPLICATIONS
    5.
    发明申请
    BIOELECTRIC BATTERY FOR IMPLANTABLE DEVICE APPLICATIONS 有权
    用于可植入器件应用的BIOELECTRIC BATTERY

    公开(公告)号：US20110202105A1

    公开(公告)日：2011-08-18

    申请号：US13018140

    申请日：2011-01-31

    申请人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    发明人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    IPC分类号： A61N1/362 ,  H01M8/16

    CPC分类号： A61N1/378 ,  H01M2/0275 ,  H01M2/1066 ,  H01M2/1653 ,  H01M2/18 ,  H01M2/361 ,  H01M4/12 ,  H01M4/366 ,  H01M4/48

    摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.

    摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。

    Bioelectric battery for implantable device applications
    6.
    发明授权
    Bioelectric battery for implantable device applications 有权
    用于植入式设备应用的生物电池

    公开(公告)号：US08709631B1

    公开(公告)日：2014-04-29

    申请号：US11737307

    申请日：2007-04-19

    申请人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    发明人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    IPC分类号： H01M4/00 ,  H01M8/16

    CPC分类号： A61N1/362 ,  A61N1/378 ,  H01M4/466 ,  H01M4/92 ,  H01M12/06 ,  H01M2220/30 ,  Y02E60/50

    摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.

    摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。

    Bioelectric battery for implantable device applications
    7.
    发明授权
    Bioelectric battery for implantable device applications 有权
    用于植入式设备应用的生物电池

    公开(公告)号：US08574737B2

    公开(公告)日：2013-11-05

    申请号：US13018140

    申请日：2011-01-31

    申请人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    发明人： Naixiong Jiang ,  Gene A. Bornzin ,  John W. Poore ,  Sheldon Williams ,  Weiqun Yang ,  Taraneh Ghaffari Farazi

    IPC分类号： H01M4/00 ,  H01M8/16 ,  H01M4/02 ,  H01M2/16

    CPC分类号： A61N1/378 ,  H01M2/0275 ,  H01M2/1066 ,  H01M2/1653 ,  H01M2/18 ,  H01M2/361 ,  H01M4/12 ,  H01M4/366 ,  H01M4/48

    摘要： A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.

    摘要翻译： 生物电池可用于为可植入装置供电。 生物电池可以具有由包括具有第一端和第二端的管的绝缘构件分开的阳极电极和阴极电极，其中所述阳极插入所述管的所述第一端，所述阴极围绕所述管，使得 管为阴极提供支撑。 生物电池还可以具有围绕阴极的膜以减少组织包封。 或者，阳极电极，围绕阴极电极的阴极电极，围绕阴极电极的可渗透膜。 电解质设置在可渗透膜内，并且网围绕可渗透膜。 在替代实施例中，起搏器壳体用作生物电池的阴极电极，并且阳极通过绝缘粘合剂附接到壳体。

    Packaging sensors for long term implant
    8.
    发明授权
    Packaging sensors for long term implant 有权
    用于长期植入的包装传感器

    公开(公告)号：US07347826B1

    公开(公告)日：2008-03-25

    申请号：US10688687

    申请日：2003-10-16

    申请人： Annapurna Karicherla ,  John W. Poore

    发明人： Annapurna Karicherla ,  John W. Poore

    IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/02

    CPC分类号： A61B5/0215 ,  A61B2562/242 ,  A61N1/375

    摘要： According to this technique of packaging a sensor device implantable in a living body so as to provide protection of the sensor device and to the living body itself, an electrical conductor of the sensor device is sealed in an insulating substrate extending between proximal and distal ends. The distal end of the electrical conductor is externally connected to an external sensor on the sensor device and the proximal end of the electrical conductor is externally connected to a distal end of a lead wire extending proximally to a pulse generator and these connections are embedded in an insulative sheath. The external sensor, substrate, and insulative sheath are encapsulated in a thin film of hermetic material without interference with the lead wire. In another embodiment, a layer of insulating material may underlie the hermetic material to encapsulate the external sensor and the substrate.

    摘要翻译： 根据这种将植入生物体的传感器装置进行包装以提供对传感器装置和生物体本身的保护的技术，传感器装置的电导体被密封在在近端和远端之间延伸的绝缘基片中。 电导体的远端外部连接到传感器装置上的外部传感器，并且电导体的近端外部连接到向近端延伸到脉冲发生器的引线的远端，并且这些连接被嵌入到 绝缘护套。 外部传感器，基板和绝缘护套被封装在密封材料的薄膜中，而不会干扰引线。 在另一个实施例中，绝缘材料层可以位于密封材料的下面，以封装外部传感器和基板。

    SYSTEM AND METHOD OF IMPLANTING A MEDICAL DEVICE
    9.
    发明申请
    SYSTEM AND METHOD OF IMPLANTING A MEDICAL DEVICE 审中-公开
    植入医疗装置的系统和方法

    公开(公告)号：US20140018818A1

    公开(公告)日：2014-01-16

    申请号：US13547791

    申请日：2012-07-12

    申请人： Zoltan Somogyi ,  Edward Karst ,  Gene A. Bornzin ,  John W. Poore ,  Richard Samade ,  Didier Theret

    发明人： Zoltan Somogyi ,  Edward Karst ,  Gene A. Bornzin ,  John W. Poore ,  Richard Samade ,  Didier Theret

    IPC分类号： A61N1/05

    CPC分类号： A61N1/372 ,  A61B17/3468 ,  A61N1/37205

    摘要： A system for implanting an implantable medical device (IMD) within a patient may include a main handle assembly having proximal and distal ends, a device-connection control handle connected to the proximal end of the main handle assembly, an introducer connected to the distal end of the main handle assembly, and a connection tool extending from the introducer. The connection tool may include a device-engaging member configured to change at least one of shape or orientation to selectively connect to and disconnect from the IMD. The device-connection control handle may be operatively connected to the device-engaging member and the device-connection control handle may be configured to manipulate the device-engaging member between connected and disconnected states by changing the at least one of the shape or orientation.

    摘要翻译： 用于在患者体内植入可植入医疗装置（IMD）的系统可以包括具有近端和远端的主手柄组件，连接到主手柄组件的近端的装置连接控制手柄，连接到远端的导引器 的主把手组件，以及从导引器延伸的连接工具。 连接工具可以包括被配置为改变形状或取向中的至少一个以选择性地连接到IMD并与IMD断开连接的装置接合构件。 设备连接控制手柄可以可操作地连接到装置接合构件，并且装置连接控制手柄可以被配置成通过改变形状或取向中的至少一个来在连接状态和断开状态之间操纵装置接合构件。