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    Pressure sensor and method of fabricating such a module
    4.
    发明授权
    Pressure sensor and method of fabricating such a module 有权
    压力传感器及其制造方法

    公开(公告)号：US07418868B1

    公开(公告)日：2008-09-02

    申请号：US11359952

    申请日：2006-02-21

    申请人： Annapurna Karicherla ,  Sheldon Williams ,  Gene A. Bornzin ,  John W. Poore ,  Dion F. Davis

    发明人： Annapurna Karicherla ,  Sheldon Williams ,  Gene A. Bornzin ,  John W. Poore ,  Dion F. Davis

    IPC分类号： G01L7/00

    CPC分类号： G01L19/142 ,  G01L19/0046 ,  G01L19/0061 ,  G01L19/0645

    摘要： A body fluid pressure sensor module according to the invention comprises a housing having a first end and a second end and enclosing a pressure sensor. The pressure sensor is electrically coupled to a plurality of electrical conductors extending into the housing through a feedthrough disposed within, and hermetically sealing, the first end of the housing. The housing defines a chamber disposed between the feedthrough and the second end of the housing. The chamber contains a material in communication with the pressure sensor, the material being capable of transmitting pressure variations to the pressure sensor. The plurality of electrical conductors have ends within the housing, and the pressure sensor is mounted on the end of at least one of the conductors. Also disclosed are medical leads incorporating the pressure sensor module, and methods for fabricating the modules. The pressure sensor module is compact, and particularly so where cable conductors are utilized and the sensor is directly mounted on at least one of the cable conductors. The compactness of a pressure sensor module pursuant to the invention facilitates its incorporation into a small diameter, flexible medical lead enhancing its placement within a patient's body, for example, within the left atrium of the heart.

    摘要翻译： 根据本发明的体液压力传感器模块包括具有第一端和第二端并且包围压力传感器的壳体。 压力传感器电耦合到通过设置在壳体的第一端内并且密封地密封壳体中的馈通部延伸到壳体中的多个电导体。 壳体限定设置在馈通和壳体的第二端之间的室。 该室包含与压力传感器连通的材料，该材料能够将压力变化传递到压力传感器。 多个电导体具有在壳体内的端部，并且压力传感器安装在至少一个导体的端部上。 还公开了结合压力传感器模块的医疗引线以及用于制造模块的方法。 压力传感器模块是紧凑的，特别是在使用电缆导体并且传感器直接安装在至少一个电缆导体上的情况下。 根据本发明的压力传感器模块的紧凑性便于其结合到小直径的柔性医疗引线中，从而增强其在患者身体内的放置，例如在心脏的左心房内。

    IMPLANTABLE ECHO DOPPLER FLOW SENSOR FOR MONITORING OF HEMODYNAMICS
    5.
    发明申请
    IMPLANTABLE ECHO DOPPLER FLOW SENSOR FOR MONITORING OF HEMODYNAMICS 审中-公开
    用于监测血液动力学的可植入式ECHO多普勒流量传感器

    公开(公告)号：US20120197141A1

    公开(公告)日：2012-08-02

    申请号：US13016101

    申请日：2011-01-28

    申请人： Guy Vanney ,  Thao Ngo ,  Scott Sjoquist ,  Dorab N. Sethna ,  Annapurna Karicherla ,  George K. Lewis ,  Dan E. Gutfinger ,  Gene A. Bornzin

    发明人： Guy Vanney ,  Thao Ngo ,  Scott Sjoquist ,  Dorab N. Sethna ,  Annapurna Karicherla ,  George K. Lewis ,  Dan E. Gutfinger ,  Gene A. Bornzin

    IPC分类号： A61B5/026

    CPC分类号： A61B5/026 ,  A61B5/02158 ,  A61B5/6846 ,  A61B5/6856 ,  A61B5/6858 ,  A61B5/686 ,  A61B5/6862 ,  A61B5/6869 ,  A61B5/6882 ,  A61B8/06 ,  A61B8/065 ,  A61B8/12 ,  A61B8/445

    摘要： Systems, devices and methods of monitoring blood flow velocity are disclosed herein. For example, one method of monitoring blood flow velocity includes: locating a blood flow velocity sensor near the ostium in the coronary sinus; and sensing towards a portion of the aorta. A second example method includes: locating a blood flow velocity sensor in a vein; and sensing towards an adjacent artery. A third example method includes: locating a blood flow velocity sensor near the tricuspid valve; and sensing towards a tricuspid valve annulus. A fourth example method includes: locating a blood flow velocity sensor right ventricular outflow tract; and sensing towards a portion of the aorta. A fifth example method includes: locating a blood flow velocity sensor in the great cardiac vein; and sensing towards a left anterior descending artery. A sixth example method includes: locating a blood flow velocity sensor in the right atrial appendage; and sensing towards a portion of the aorta.

    摘要翻译： 本文公开了监测血流速度的系统，装置和方法。 例如，监测血流速度的一种方法包括：将血流速度传感器定位在冠状窦口附近; 并且朝向主动脉的一部分进行感测。 第二示例性方法包括：将血流速度传感器定位在静脉中; 并向相邻动脉进行感测。 第三示例性方法包括：在三尖瓣附近定位血流速度传感器; 并向三尖瓣环进行感测。 第四示例性方法包括：定位血流速度传感器右心室流出道; 并且朝向主动脉的一部分进行感测。 第五示例方法包括：在大心脏静脉中定位血流速度传感器; 并向左前降支动脉进行感测。 第六示例性方法包括：在右心耳中定位血流速度传感器; 并且朝向主动脉的一部分进行感测。

    Trans-septal intra-cardiac lead system
    6.
    发明授权
    Trans-septal intra-cardiac lead system 失效
    跨隔间心脏引导系统

    公开(公告)号：US07389134B1

    公开(公告)日：2008-06-17

    申请号：US11053374

    申请日：2005-02-07

    申请人： Annapurna Karicherla ,  Kevin L. Morgan ,  Gene A. Bornzin ,  Sheldon Williams

    发明人： Annapurna Karicherla ,  Kevin L. Morgan ,  Gene A. Bornzin ,  Sheldon Williams

    IPC分类号： A61B5/04 ,  A61B5/02

    CPC分类号： A61B5/0215 ,  A61B5/042

    摘要： An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.

    摘要翻译： 公开了一种通过患者心脏中的隔膜测量压力的装置和方法。 插入心脏右侧的导线穿过隔膜，以进入心脏的左侧。 引线包括将引线固定到一个或两个隔膜壁的附接结构。 附接结构可以包括接合隔膜的一侧或多侧的至少一个突出的齿，膜，可充气气囊，渐开线螺旋或J-引线。 引线还包括一个或多个用于测量心脏左侧的心脏压力和根据需要的心脏的右侧的传感器。

    Multi-site pacing for atrial tachyarrhythmias
    7.
    发明授权
    Multi-site pacing for atrial tachyarrhythmias 有权
    多节段起搏用于房性快速性心律失常

    公开(公告)号：US07917216B1

    公开(公告)日：2011-03-29

    申请号：US11458649

    申请日：2006-07-19

    申请人： Kyungmoo Ryu ,  Jong Gill ,  Xiaoyi Min ,  Annapurna Karicherla ,  Gene A. Bornzin

    发明人： Kyungmoo Ryu ,  Jong Gill ,  Xiaoyi Min ,  Annapurna Karicherla ,  Gene A. Bornzin

    IPC分类号： A61N1/18

    CPC分类号： A61N1/3622 ,  A61N1/0587 ,  A61N1/3686

    摘要： Tachyarrhythmia is treated by applying anti-tachycardia pacing through at least one multi-site electrode set located on, in or around the heart. The electrode set is arranged and located such that an electrical activation pattern having a wave-front between substantially flat and concave is generated through a reentrant circuit associated with the tachyarrhythmia. The electrode set may be one of a plurality of predefined, multi-site electrode sets located on, in or around the atria. Alternatively, the electrode set may be formed using at least two selectable electrodes located on, in or around the atria.

    摘要翻译： 通过应用抗心动过速起搏通过位于心脏内或心脏周围的至少一个多位点电极组来治疗快速性心律失常。 电极组被布置和定位成使得通过与快速性心律失常相关联的折返电路产生具有基本上平坦和凹陷之间的波前的电激活模式。 电极组可以是位于心房内或周围的多个预定义的多位点电极组之一。 或者，可以使用位于心房内或周围的至少两个可选择电极来形成电极组。