摘要:
Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
摘要:
Fused heteroaryl pyridyl benzenesulfonamides are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
摘要:
Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
摘要:
Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
摘要:
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
摘要:
FIG. 1 is a perspective view of a charging socket showing the new design; FIG. 2 is another perspective view thereof; FIG. 3 is a front elevation view thereof; FIG. 4 is a back elevation view thereof; FIG. 5 is a left-side elevation view thereof; FIG. 6 is a right-side elevation view thereof; FIG. 7 is a top plan view thereof; and FIG. 8 is a bottom plan view thereof. FIG. 9 is an enlarged partial view of area ‘9’ in FIG. 1. FIG. 10 is an enlarged partial view of area ‘10’ in FIG. 2; and, FIG. 11 is an enlarged partial view of area ‘11’ in FIG. 2. The dash-dash broken lines in the drawings illustrate portions of the charging socket that form no part of the claimed design. The dash-dot broken lines illustrate the boundaries of the portions shown enlarged and form no part of the claimed design.
摘要:
Systems and methods for scanning signatures in a string field. In one implementation, the invention provides a method for signature scanning. The method includes receiving a particular string field, scanning the particular string field for a plurality of signatures using a larger scan step size, scanning the particular string field for the remaining signatures that are shorter than what can be scanned by the larger scan step size separately either using the same scanning method but a smaller scan step size or using a different scan method and the same or a smaller scan step size, and outputting any identified signatures in the particular string field.
摘要:
A positron emission tomography (PET) technique that can enhance the image resolution and system sensitivity of a clinical PET/CT scanner for imaging a whole body or a target region of a subject is provided. The system includes a detector array and a detector panel. The detector array includes an array of gamma ray detectors defining a field of view of a scanner and configured to detect at least one coincidence event. The detector panel includes an array of gamma ray detectors having a higher intrinsic spatial resolution than the detector array and positioned in closer proximity to a patient table than the detector array. The detector panel is positioned outside the field of view defined by the detector array during at least a portion of scanning by the PET system. The detector panel is configured to detect at least one coincidence event in cooperation with the detector array. The control unit is configured to control the detector array, the detector panel, and the patient bed to operate in cooperation with each other.