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1.发明申请Use of Secretor, Lewis and Sialyl Antigen Levels in Clinical Samples as Predictors of Risk for Disease 有权在临床样本中使用分泌者，Lewis和唾液酸抗原水平作为疾病风险的预测因子公开(公告)号：US20090191551A1
公开(公告)日：2009-07-30
申请号：US12205089
申请日：2008-09-05
CPC分类号： A61K31/7028 , A61K31/702 , A61K31/715 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/02 , A61K45/06 , G01N33/6893 , G01N33/80 , G01N2800/067 , Y02A50/471 , Y02A50/473 , Y02A50/491 , Y02A50/52
摘要： An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
摘要翻译： 可以通过测量来自个体的生物样品中的至少一种分泌型抗原的水平来鉴定坏死性小肠结肠炎和相关疾病风险的个体，并将所测量的至少一种分泌型抗原的水平与预定值或预定范围进行比较 的价值观。 可以测量的分泌抗原是：H-1，H-2，Lewisb和Lewisy抗原及其衍生物（例如，路易斯a的唾液酸化形式，路易斯x，路易斯b，路易斯y; H-1，H -2，Lewis a，Lewis x，Lewis b或Lewis y）。
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公开(公告)号：US09034847B2
公开(公告)日：2015-05-19
申请号：US13382323
申请日：2010-07-02
IPC分类号： A61K31/702 , A61K47/48 , A61P31/00 , A61P31/04 , A61P1/00 , A61P1/04 , A61P1/12 , A61P29/00 , A61K35/20
CPC分类号： A61K31/7016 , A61K31/702 , A61K35/20 , A61K47/50 , A61K47/61 , A61K47/62
摘要： A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.
摘要翻译： 公开了一种抑制受试者炎症的方法，包括给予含有乳寡糖的乳寡糖或糖缀合物。
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3.发明申请OLIGOSACCHARIDE COMPOSITIONS AND USE THEREOF IN THE TREATMENT OF INFECTION 审中-公开低密度脂蛋白组合物及其在感染治疗中的应用公开(公告)号：US20110207659A1
公开(公告)日：2011-08-25
申请号：US13032568
申请日：2011-02-22
IPC分类号： A61K38/16 , C12N9/20 , C12N1/19 , C07H21/04 , A61P31/04 , A61K31/715 , C12N9/36 , C12N9/08 , C12N9/26
CPC分类号： A61K31/702 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K35/20 , A61K38/00 , A61K45/06 , Y02A50/47 , Y02A50/475 , A23V2200/324 , A23V2250/28 , A23V2250/54
摘要： Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.
摘要翻译： 描述了与骨架如蛋白质连接的寡糖和寡糖，制备这种寡糖的方法以及用于治疗和/或预防各种疾病的方法。
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公开(公告)号：US20120202753A1
公开(公告)日：2012-08-09
申请号：US13382323
申请日：2010-07-02
IPC分类号： A61K31/7016 , A61K31/702 , A61P29/00 , A61K38/14
CPC分类号： A61K31/7016 , A61K31/702 , A61K35/20 , A61K47/50 , A61K47/61 , A61K47/62
摘要： A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.
摘要翻译： 公开了一种抑制受试者炎症的方法，包括给予含有乳寡糖的乳寡糖或糖缀合物。
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5.发明申请USE OF SECRETOR, LEWIS AND SIALYL ANTIGEN LEVELS IN CLINICAL SAMPLES AS PREDICTORS OF RISK FOR DISEASE 有权临床样本中的秘密，LEWIS和SIALYL抗原水平的使用作为疾病风险的预防因素公开(公告)号：US20110177035A1
公开(公告)日：2011-07-21
申请号：US13006795
申请日：2011-01-14
CPC分类号： A61K31/7028 , A61K31/702 , A61K31/715 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/02 , A61K45/06 , G01N33/6893 , G01N33/80 , G01N2800/067 , Y02A50/471 , Y02A50/473 , Y02A50/491 , Y02A50/52
摘要： An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
摘要翻译： 可以通过测量来自个体的生物样品中的至少一种分泌型抗原的水平来鉴定坏死性小肠结肠炎和相关疾病风险的个体，并将所测量的至少一种分泌型抗原的水平与预定值或预定范围进行比较 的价值观。 可以测量的分泌抗原是：H-1，H-2，Lewisb和Lewisy抗原及其衍生物（例如，路易斯a的唾液酸化形式，路易斯x，路易斯b，路易斯y; H-1，H -2，Lewis a，Lewis x，Lewis b或Lewis y）。
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6.发明授权公开(公告)号：US07893041B2
公开(公告)日：2011-02-22
申请号：US10581759
申请日：2004-12-06
IPC分类号： A61K31/702 , A61K38/38
CPC分类号： A61K31/702 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K35/20 , A61K38/00 , A61K45/06 , Y02A50/47 , Y02A50/475 , A23V2200/324 , A23V2250/28 , A23V2250/54
摘要： Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.
摘要翻译： 描述了与骨架如蛋白质连接的寡糖和寡糖，制备这种寡糖的方法以及用于治疗和/或预防各种疾病的方法。
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7.发明授权Use of secretor, Lewis and sialyl antigen levels in clinical samples as predictors of risk for disease 有权在临床样本中使用分泌物，Lewis和唾液酸抗原水平作为疾病风险的预测因子公开(公告)号：US07871785B2
公开(公告)日：2011-01-18
申请号：US12205089
申请日：2008-09-05
IPC分类号： G01N33/53
CPC分类号： A61K31/7028 , A61K31/702 , A61K31/715 , A61K35/741 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/02 , A61K45/06 , G01N33/6893 , G01N33/80 , G01N2800/067 , Y02A50/471 , Y02A50/473 , Y02A50/491 , Y02A50/52
摘要： An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1 , H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).
摘要翻译： 可以通过测量来自个体的生物样品中的至少一种分泌型抗原的水平来鉴定坏死性小肠结肠炎和相关疾病风险的个体，并将所测量的至少一种分泌型抗原的水平与预定值或预定范围进行比较 的价值观。 可以测量的分泌抗原是：H-1，H-2，Lewisb和Lewisy抗原及其衍生物（例如，路易斯a的唾液酸化形式，路易斯x，路易斯b，路易斯y; H-1，H -2，Lewis a，Lewis x，Lewis b或Lewis y）。
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