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公开(公告)号：US20080241212A1
公开(公告)日：2008-10-02
申请号：US12058060
申请日：2008-03-28
申请人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Irene Shatova , Archana Rajaram
发明人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Irene Shatova , Archana Rajaram
IPC分类号： A61F2/12 , A61K31/496 , A61K31/65 , A61K31/7036 , A61K38/00 , A61K31/7048 , A61K31/545 , A61K31/47 , A61K31/41 , A61K31/404 , A61K31/381 , A61K31/167 , A61K31/445 , A61P29/00 , A61P17/00
CPC分类号： A61F2/12 , A61K31/167 , A61K31/381 , A61K31/404 , A61K31/41 , A61K31/445 , A61K31/47 , A61K31/496 , A61K31/545 , A61K31/65 , A61K31/7036 , A61K31/7048 , A61K38/13 , B29C41/14 , A61K2300/00
摘要： A biodegradable, flexible covering for a breast implant is provided which comprises one or more biodegradable polymer layers dimensioned and shaped to cover at least a portion of the breast implant. The implant can be inserted into an opening of the covering immediately prior to surgery, but alternate configurations and times of insertion are contemplated as well as open or sheet type devices. The coverings can optionally contain one or more drugs for delivery at the surgical site, particularly for treating or preventing infection, pain, inflammation, capsular contracture, scarring or other complications associated with breast augmentation or breast reconstruction.
摘要翻译： 提供了一种用于乳房植入物的可生物降解的柔性覆盖物，其包括尺寸和形状以覆盖乳房植入物的至少一部分的一个或多个可生物降解的聚合物层。 植入物可以在手术之前立即插入覆盖物的开口中，但可以考虑插入的交替构型和时间以及开式或片式装置。 覆盖物可任选地含有一种或多种用于在手术部位递送的药物，特别是用于治疗或预防感染，疼痛，炎症，囊肿挛缩，瘢痕或与隆胸或乳房重建相关的其他并发症。
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公开(公告)号：US08911765B2
公开(公告)日：2014-12-16
申请号：US12058060
申请日：2008-03-28
申请人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Irene Shatova , Archana Rajaram
发明人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Irene Shatova , Archana Rajaram
IPC分类号： A61F2/12 , A61K31/496 , A61K31/65 , A61K31/7036 , A61K38/00 , A61K31/48 , A61K31/545 , A61K31/47 , A61K31/41 , A61K31/404 , A61K31/381 , A61K31/167 , A61K31/445 , A61K38/13 , A61K31/7048 , B29C41/14
CPC分类号： A61F2/12 , A61K31/167 , A61K31/381 , A61K31/404 , A61K31/41 , A61K31/445 , A61K31/47 , A61K31/496 , A61K31/545 , A61K31/65 , A61K31/7036 , A61K31/7048 , A61K38/13 , B29C41/14 , A61K2300/00
摘要： A biodegradable, flexible covering for a breast implant is provided which comprises one or more biodegradable polymer layers dimensioned and shaped to cover at least a portion of the breast implant. The implant can be inserted into an opening of the covering immediately prior to surgery, but alternate configurations and times of insertion are contemplated as well as open or sheet type devices. The coverings can optionally contain one or more drugs for delivery at the surgical site, particularly for treating or preventing infection, pain, inflammation, capsular contracture, scarring or other complications associated with breast augmentation or breast reconstruction.
摘要翻译： 提供了一种用于乳房植入物的可生物降解的柔性覆盖物，其包括尺寸和形状以覆盖乳房植入物的至少一部分的一个或多个可生物降解的聚合物层。 植入物可以在手术之前立即插入覆盖物的开口中，但可以考虑插入的交替构型和时间以及开式或片式装置。 覆盖物可任选地含有一种或多种用于在手术部位递送的药物，特别是用于治疗或预防感染，疼痛，炎症，囊肿挛缩，瘢痕或与隆胸或乳房重建相关的其他并发症。
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公开(公告)号：US20100129417A1
公开(公告)日：2010-05-27
申请号：US12598559
申请日：2008-05-02
申请人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Archana Rajaram
发明人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Archana Rajaram
IPC分类号： A61K31/65 , A61F2/00 , A61K31/496 , C08L67/02 , C08G63/133 , A61P27/02 , A61P9/00 , A61P25/00
CPC分类号： A23L3/3481 , A61K31/765 , A61K45/06 , A61K2300/00
摘要： The present invention is directed to polyphenolic polymers formed from dihydroxybenzoic acid (DHB) derivatives or from resorcinol derivatives, monomers which form such polymers, blends of the polymers with drugs and/or additional polymers, as well as medical devices formed from, coated with, impregnated by or coverings made with any of the foregoing polymers (with or without drugs) or blends (with or without drugs).
摘要翻译： 本发明涉及由二羟基苯甲酸（DHB）衍生物或间苯二酚衍生物形成的多酚聚合物，形成这种聚合物的单体，聚合物与药物和/或另外的聚合物的共混物，以及由涂覆， 用任何前述聚合物（含或不含药物）或共混物（含或不含药物）制成的浸渍或覆盖物。
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公开(公告)号：US09491966B2
公开(公告)日：2016-11-15
申请号：US12598559
申请日：2008-05-02
申请人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Archana Rajaram
发明人： Arikha Moses , Satish Pulapura , Qing Ge , Sarita Nethula , Archana Rajaram
IPC分类号： A61K31/65 , A61F2/00 , A61K31/496 , A61P25/00 , A61P27/02 , A61P9/00 , C08G63/133 , C08L67/02 , A23L3/3481 , A61K31/765 , A61K45/06
CPC分类号： A23L3/3481 , A61K31/765 , A61K45/06 , A61K2300/00
摘要： The present invention is directed to polyphenolic polymers formed from dihydroxybenzoic acid (DHB) derivatives or from resorcinol derivatives, monomers which form such polymers, blends of the polymers with drugs and/or additional polymers, as well as medical devices formed from, coated with, impregnated by or coverings made with any of the foregoing polymers (with or without drugs) or blends (with or without drugs).
摘要翻译： 本发明涉及由二羟基苯甲酸（DHB）衍生物或间苯二酚衍生物形成的多酚聚合物，形成这种聚合物的单体，聚合物与药物和/或另外的聚合物的共混物，以及由涂覆， 用任何前述聚合物（含或不含药物）或共混物（含或不含药物）制成的浸渍或覆盖物。
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公开(公告)号：US08445603B2
公开(公告)日：2013-05-21
申请号：US12564736
申请日：2009-09-22
IPC分类号： C08F283/04
CPC分类号： C08G69/44 , A61K9/0024 , A61K31/09 , A61K31/4465 , A61K31/496 , A61K31/65 , A61K31/7036 , A61K47/34 , A61L29/06 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/06 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/802 , A61L2400/18 , A61L2420/06 , A61M2025/0057 , C08G69/00 , C08L77/12 , C08L101/00 , C08L2666/02 , C08L2666/20
摘要： The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
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公开(公告)号：US20100074940A1
公开(公告)日：2010-03-25
申请号：US12564736
申请日：2009-09-22
IPC分类号： A61K47/30 , C08G69/08 , A61K31/497 , A61K31/65 , A61K31/7036 , A61K38/14 , A61K31/075 , A61F2/02 , A61F2/82
CPC分类号： C08G69/44 , A61K9/0024 , A61K31/09 , A61K31/4465 , A61K31/496 , A61K31/65 , A61K31/7036 , A61K47/34 , A61L29/06 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/06 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/802 , A61L2400/18 , A61L2420/06 , A61M2025/0057 , C08G69/00 , C08L77/12 , C08L101/00 , C08L2666/02 , C08L2666/20
摘要： The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
摘要翻译： 本发明涉及由衍生自氨基苯酚酯和二酸的重复单元合成的线性可生物降解聚酯酰胺（PEA）聚合物。 这些PEAs具有由包括，形成或包括医疗装置，组合医疗装置和药物组合物（包括持续释放制剂）的多种用途所代表的单体重复。
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公开(公告)号：US08471054B2
公开(公告)日：2013-06-25
申请号：US13414090
申请日：2012-03-07
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
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公开(公告)号：US08153837B2
公开(公告)日：2012-04-10
申请号：US12279539
申请日：2006-11-03
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
摘要翻译： 本发明提供具有式（I），式（II），式（III）或式（IV））的单体单元的生物相容性可再吸收聚合物。 当植入体内时，聚合物随时间降解，并且可用作可植入医疗装置的组件。
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公开(公告)号：US20090088548A1
公开(公告)日：2009-04-02
申请号：US12279539
申请日：2006-11-03
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
IPC分类号： C08G63/193 , C07C229/36
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
摘要翻译： 本发明提供具有式（I），式（II），式（III）或式（IV））的单体单元的生物相容性可再吸收聚合物。 当植入体内时，聚合物随时间降解，并且可用作可植入医疗装置的组件。
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公开(公告)号：US20120165495A1
公开(公告)日：2012-06-28
申请号：US13414090
申请日：2012-03-07
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
IPC分类号： C08G63/193 , C07H15/18 , C07C69/716 , C07C235/52 , C07C237/52
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
摘要翻译： 本发明提供具有式（I），式（II），式（III）或式（IV））的单体单元的生物相容性可再吸收聚合物。 当植入体内时，聚合物随时间降解，并且可用作可植入医疗装置的组件。
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