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公开(公告)号：US5788972A
公开(公告)日：1998-08-04
申请号：US547146
申请日：1995-10-24
IPC分类号： C12N9/20 , A61K8/00 , A61K8/11 , A61K8/30 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/66 , A61K8/67 , A61K8/72 , A61K8/891 , A61K8/92 , A61K8/96 , A61K9/00 , A61K47/46 , A61P17/12 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/00 , A61K47/46 , A61K8/37 , A61K8/66 , A61K8/671 , A61K8/676 , A61K9/0014 , A61Q19/04 , A61Q19/08 , A61Q19/02 , Y10S514/844 , Y10S514/846 , Y10S514/847 , Y10S514/937
摘要： The present invention concerns a product for topical application, capable of releasing a cosmetic and/or dermatological active ingredient in and/or on the skin, containing a lipase enzyme and at least one ester precursor of the active ingredient. The ester contains an ester functional group having a saturated or unsaturated, linear or branched chain having from 2 to 25 carbon atoms. According to a preferred embodiment, the precursor and lipase are packaged so as not to be in contact with one another until the time of application to the skin.
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2.发明授权Product for topical application containing a lipase and an active ingredient precursor 失效用于含有脂肪酶和活性成分前体的局部施用的产品
公开(公告)号：US5932232A
公开(公告)日：1999-08-03
申请号：US946858
申请日：1997-10-08
IPC分类号： C12N9/20 , A61K8/00 , A61K8/11 , A61K8/30 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/66 , A61K8/67 , A61K8/72 , A61K8/891 , A61K8/92 , A61K8/96 , A61K9/00 , A61K47/46 , A61P17/12 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/00 , A61K47/46 , A61K8/37 , A61K8/66 , A61K8/671 , A61K8/676 , A61K9/0014 , A61Q19/04 , A61Q19/08 , A61Q19/02 , Y10S514/844 , Y10S514/846 , Y10S514/847 , Y10S514/937
摘要： The present invention concerns a product for topical application, capable of releasing a cosmetic and/or dermatological active ingredient in and/or on the skin, containing a lipase enzyme and at least one ester precursor of the active ingredient. The ester contains an ester functional group having a saturated or unsaturated, linear or branched chain having from 2 to 25 carbon atoms. According to a preferred embodiment, the precursor and lipase are packaged so as not to be in contact with one another until the time of application to the skin.
摘要翻译： 本发明涉及用于局部应用的产品，其能够释放含有脂肪酶和活性成分的至少一种酯前体的皮肤中和/或皮肤上的化妆品和/或皮肤病学活性成分。 该酯含有具有2至25个碳原子的饱和或不饱和的直链或支链的酯官能团。 根据优选的实施方案，将前体和脂肪酶包装成彼此不接触直至施用于皮肤的时间为止。
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公开(公告)号：US5693670A
公开(公告)日：1997-12-02
申请号：US534314
申请日：1995-09-27
申请人： Michel Philippe , Remy Tuloup , Armelle de Salvert , Daniel Sera , Pierre Fodor
发明人： Michel Philippe , Remy Tuloup , Armelle de Salvert , Daniel Sera , Pierre Fodor
IPC分类号： A61K8/35 , A61K8/37 , A61K8/44 , A61K8/66 , A61K31/235 , A61K31/25 , A61K38/46 , A61Q19/04 , A61K31/12
摘要： The invention relates to a composition, which may be cosmetic or dermatological, Containing at least one dihydroxyacetone precursor. The invention also relates to a composition, which may be cosmetic or dermatological, containing at least one dihydroxyacetone precursor and a compound capable of converting this precursor into dihydroxyacetone. Finally, the invention relates to such a composition packaged in a specific manner and to the use of the composition for artificial tanning of the skin.
摘要翻译： 本发明涉及一种组合物，其可以是化妆品或皮肤病学的，含有至少一种二羟基丙酮前体。 本发明还涉及包含至少一种二羟基丙酮前体和能够将该前体转化为二羟基丙酮的化合物的化妆品或皮肤病学的组合物。 最后，本发明涉及以特定方式包装的这种组合物以及用于皮肤的人造鞣制的组合物的用途。
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公开(公告)号：US5653984A
公开(公告)日：1997-08-05
申请号：US499915
申请日：1995-07-11
申请人： Pierre Fodor , Gerard Guth , Emmanuelle Maurin
发明人： Pierre Fodor , Gerard Guth , Emmanuelle Maurin
IPC分类号： C12P21/00 , A61K8/00 , A61K8/02 , A61K8/36 , A61K8/365 , A61K8/44 , A61K8/64 , A61K8/73 , A61K8/96 , A61K8/97 , A61K31/70 , A61K36/00 , A61K36/22 , A61K36/24 , A61K36/736 , A61K38/00 , A61P17/00 , A61P43/00 , A61Q5/00 , A61Q19/00 , A61Q19/08 , A61K35/78
CPC分类号： A61Q19/00 , A61K36/22 , A61K36/736 , A61K8/0212 , A61K8/44 , A61K8/645 , A61K8/97 , A61K2800/85 , A61Q17/00
摘要： Extracts of periwinkle seed, obtained by bioconversion, and compositions containing such extracts display the property of stimulating mitochondrial cell respiration and of stimulating the cell growth of fibroblasts and keratinocytes. Such extracts and compositions also exhibit activity against oxygen free radicals.
摘要翻译： 通过生物转化获得的长春花籽提取物和含有这些提取物的组合物显示刺激线粒体细胞呼吸和刺激成纤维细胞和角质形成细胞的细胞生长的性质。 这些提取物和组合物还表现出抗氧自由基的活性。
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公开(公告)号：US5738839A
公开(公告)日：1998-04-14
申请号：US470493
申请日：1995-06-06
申请人： Anne Clement , Pierre Fodor , Gerard Guth , Nathalie Thiollet
发明人： Anne Clement , Pierre Fodor , Gerard Guth , Nathalie Thiollet
IPC分类号： A61K8/02 , A61K8/06 , A61K8/11 , A61K8/35 , A61K8/41 , A61K8/44 , A61K8/67 , A61K8/73 , A61K9/00 , A61K9/107 , A61K9/16 , A61K47/32 , A61Q19/00 , B01J13/00 , A61K9/10
CPC分类号： A61K9/1652 , A61K47/32 , A61K8/044 , A61K8/11 , A61K8/35 , A61K8/44 , A61K8/676 , A61K8/733 , A61K9/0014 , A61K9/107 , A61Q19/00 , A61K2800/412 , Y10S514/936 , Y10S514/939 , Y10S514/941 , Y10S514/944
摘要： The present invention relates to gelled emulsion particles obtained when predetermined volumes, especially drops, of an emulsion with an aqueous external phase, containing an appropriate reagent in solution in the said aqueous phase, are added to a gelling solution and left therein for a period of time which depends on the degree of gelling desired for the said particles. It further relates to compositions--especially solutions, gels or emulsions with an aqueous external phase--in which the said particles are present.
摘要翻译： 本发明涉及当在含水相中的溶液中含有适当的试剂的预定体积，特别是含有外部水相的乳液的预定体积（特别是液滴）时，获得的胶凝乳液颗粒被加入到胶凝溶液中并保留一段时间 时间取决于所述颗粒所需的胶凝程度。 它还涉及具有外部水相的组合物，特别是溶液，凝胶或乳液，其中存在所述颗粒。
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公开(公告)号：US5508022A
公开(公告)日：1996-04-16
申请号：US332497
申请日：1994-10-31
IPC分类号： A61K8/02 , A61K8/06 , A61K8/11 , A61K8/35 , A61K8/41 , A61K8/44 , A61K8/67 , A61K8/73 , A61K9/00 , A61K9/107 , A61K9/16 , A61K47/32 , A61Q19/00 , B01J13/00 , A61K9/10 , A61K7/42
CPC分类号： A61K9/1652 , A61K47/32 , A61K8/044 , A61K8/11 , A61K8/35 , A61K8/44 , A61K8/676 , A61K8/733 , A61K9/0014 , A61K9/107 , A61Q19/00 , A61K2800/412 , Y10S514/936 , Y10S514/939 , Y10S514/941 , Y10S514/944
摘要： The present invention relates to gelled emulsion particles obtained when predetermined volumes, especially drops, of an emulsion with an aqueous external phase, containing an appropriate reagent in solution in the said aqueous phase, are added to a gelling solution and left therein for a period of time which depends on the degree of gelling desired for the said particles.It further relates to compositions--especially solutions, gels or emulsions with an aqueous external phase--in which the said particles are present.
摘要翻译： 本发明涉及当在含水相中的溶液中含有适当的试剂的预定体积，特别是含有外部水相的乳液的预定体积（特别是液滴）时，获得的胶凝乳液颗粒被加入到胶凝溶液中并保留一段时间 时间取决于所述颗粒所需的胶凝程度。 它还涉及具有外部水相的组合物，特别是溶液，凝胶或乳液，其中存在所述颗粒。
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公开(公告)号：US5208028A
公开(公告)日：1993-05-04
申请号：US330601
申请日：1989-03-29
申请人： Anne Clement , Pierre Fodor , Gerard Guth , Nathalie Thiollet
发明人： Anne Clement , Pierre Fodor , Gerard Guth , Nathalie Thiollet
IPC分类号： A61K8/02 , A61K8/06 , A61K8/11 , A61K8/35 , A61K8/41 , A61K8/44 , A61K8/67 , A61K8/73 , A61K9/00 , A61K9/107 , A61K9/16 , A61K47/32 , A61Q19/00 , B01J13/00
CPC分类号： A61K9/1652 , A61K47/32 , A61K8/044 , A61K8/11 , A61K8/35 , A61K8/44 , A61K8/676 , A61K8/733 , A61K9/0014 , A61K9/107 , A61Q19/00 , A61K2800/412 , Y10S514/936 , Y10S514/939 , Y10S514/941 , Y10S514/944
摘要： The present invention relates to gelled emulsion particles obtained when predetermined volumes, especially drops, of an emulsion with an aqueous external phase, containing an appropriate reagent in solution in the said aqueous phase, are added to a gelling solution and left therein for a period of time which depends on the degree of gelling desired for the said particles. It further relates to compositions-especially solutions, gels or emulsions with an aqueous external phase-in which the said particles are present.
摘要翻译： 本发明涉及当在含水相中的溶液中含有适当的试剂的预定体积，特别是含有外部水相的乳液的预定体积（特别是液滴）时，获得的胶凝乳液颗粒被加入到胶凝溶液中并保留一段时间 时间取决于所述颗粒所需的胶凝程度。 它还涉及具有外部水相的组合物，特别是溶液，凝胶或乳液，其中存在所述颗粒。
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公开(公告)号：US5573768A
公开(公告)日：1996-11-12
申请号：US236138
申请日：1994-05-02
申请人： Isabelle Afriat , Pierre Fodor , Francoise Pouget
发明人： Isabelle Afriat , Pierre Fodor , Francoise Pouget
CPC分类号： A61Q19/00 , A61K8/042 , A61K8/8152 , A61K8/86 , A61K8/90 , A61K2800/594 , Y10S514/844 , Y10S514/944
摘要： Cosmetic composition in the form of an aqueous gel containing a gelling agent and an aqueous medium, in which the gelling agent consists of a mixture of:a) at least one at least partially neutralized, crosslinked acrylic acid polymer having a molecular weight of between 700,000 and 4,500,000 approximately,b) at least one at least partially neutralized copolymer of acrylic acid and vinyl monomer bearing amine, amidine and nitrile functions, and obtained by hydrolysis of polyacrylonitrile, having a molecular weight of between 100,000 and 200,000 approximately, andc) at least one polyethylene glycol having a molecular weight of between 10.sup.5 and 3.times.10.sup.7 approximately.
摘要翻译： 含有凝胶剂和水性介质的含水凝胶形式的化妆品组合物，其中胶凝剂由以下混合物组成：a）至少一种至少部分中和的交联丙烯酸聚合物，其分子量为70万 和约4,500,000，b）至少一种至少部分中和的丙烯酸和乙烯基单体的共聚物，其具有胺，脒和腈的功能，并且通过水解聚丙烯腈而得到，聚丙烯腈的分子量约为100,000至200,000，c） 至少一种分子量约为105至3×107的聚乙二醇。
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公开(公告)号：US5306498A
公开(公告)日：1994-04-26
申请号：US862716
申请日：1992-04-03
IPC分类号： A61K8/72 , A61K8/02 , A61K8/06 , A61K8/37 , A61K8/39 , A61K8/70 , A61K8/73 , A61K8/81 , A61K8/89 , A61K8/891 , A61K8/92 , A61K8/97 , A61K9/107 , A61K9/113 , A61Q19/00 , B01F17/52 , C08L33/02 , C08L33/04 , C08L83/04 , A61K7/00
CPC分类号： A61Q19/00 , A61K8/066 , A61K8/70 , A61K8/8152 , A61K9/113 , B01F2003/0838 , Y10S514/847 , Y10S514/937
摘要： The invention relates to a triple emulsion comprising:(A) a continuous gelled outer aqueous phase, containing, as gelling agent, at least one acrylic or methacrylic acid polymer or copolymer, combined with a polyglyceryl methacrylate;(B) a fatty phase dispersed in the outer aqueous phase, and an aqueous phase (C) dispersed in the fatty phase. Process for preparing a triple emulsion conforming to the invention.Application in cosmetics and dermatology.
摘要翻译： 本发明涉及三重乳液，其包含：（A）连续胶凝的外部水相，其含有作为胶凝剂的至少一种丙烯酸或甲基丙烯酸聚合物或共聚物，与聚甲基丙烯酸甘油酯组合; （B）分散在外部水相中的脂肪相和分散在脂肪相中的水相（C）。 制备符合本发明的三重乳液的方法。 在化妆品和皮肤病学中的应用。
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公开(公告)号：US5523091A
公开(公告)日：1996-06-04
申请号：US198057
申请日：1994-02-18
申请人： Valerie Pastour , Francoise Pouget , Pierre Fodor
发明人： Valerie Pastour , Francoise Pouget , Pierre Fodor
IPC分类号： A61K8/72 , A61K8/02 , A61K8/06 , A61K8/31 , A61K8/37 , A61K8/73 , A61K8/89 , A61K8/891 , A61K8/894 , A61K8/898 , A61K8/92 , A61K9/107 , A61K47/14 , A61K47/34 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q19/00 , C08L83/04 , C08L83/12 , A61K7/02
CPC分类号： A61K8/894 , A61K8/06 , A61K8/064 , A61K8/375 , A61Q1/02 , A61Q19/00 , Y10S514/844 , Y10S514/937
摘要： A cosmetic or pharmaceutical water-in-oil emulsion composition, exhibiting time and temperature stability, comprises in an aqueous phase, (a) a fatty phase comprising (i) a silicone and (ii) a gelling agent and (b) an emulsifying agent. The fatty phase is present in an amount ranging from 15 to 40 weight percent of the emulsion and contains 10 to 90 weight percent of the (i) silicone and 0.1 to 5 percent of the (ii) gelling agent. The emulsifying agent is present in an amount ranging from 0.5 to 10 percent by weight.
摘要翻译： 显示时间和温度稳定性的化妆品或药物油包水乳液组合物在水相中包含（a）脂肪相，其包含（i）硅氧烷和（ii）胶凝剂和（b）乳化剂 。 脂肪相的存在量为乳液的15至40重量％，并且含有10至90重量％的（i）硅氧烷和0.1至5％的（ii）胶凝剂。 乳化剂的存在量为0.5〜10重量％。
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