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公开(公告)号:US20100129804A1
公开(公告)日:2010-05-27
申请号:US12513637
申请日:2007-11-08
CPC分类号: G01N33/57434 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , G01N2333/8135
摘要: Compositions and methods for cancer research, diagnosis, and treatment, including but not limited to, cancer markers are provided. In particular, SPINK1 and other markers for prostate cancer are provided.
摘要翻译: 提供了癌症研究,诊断和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,提供SPINK1和其他前列腺癌标志物。
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公开(公告)号:US20090104120A1
公开(公告)日:2009-04-23
申请号:US12237512
申请日:2008-09-25
CPC分类号: C12Q1/6886 , C12Q2600/136
摘要: This invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, this invention relates to DLX1 cancer markers that are useful as diagnostic markers and clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及可用作诊断标志物和用于前列腺癌的临床靶标的DLX1癌症标志物。
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公开(公告)号:US20130225433A1
公开(公告)日:2013-08-29
申请号:US13780585
申请日:2013-02-28
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/156 , G01N33/57434 , G01N33/6893
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to mutations in cancer markers as diagnostic markers and clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及癌症标志物中的突变,作为前列腺癌的诊断标志物和临床靶标。
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公开(公告)号:US08058003B2
公开(公告)日:2011-11-15
申请号:US12016498
申请日:2008-01-18
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US20090075833A1
公开(公告)日:2009-03-19
申请号:US12016498
申请日:2008-01-18
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US08900819B2
公开(公告)日:2014-12-02
申请号:US13286820
申请日:2011-11-01
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
IPC分类号: G01N33/53 , G01N33/566 , C12Q1/68 , C07K16/00 , C12P21/08
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US20120046196A1
公开(公告)日:2012-02-23
申请号:US13286820
申请日:2011-11-01
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US08759301B2
公开(公告)日:2014-06-24
申请号:US13024491
申请日:2011-02-10
CPC分类号: C07K14/4702 , A61K38/00 , C07K7/06 , C07K14/82
摘要: The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症治疗的组合物和方法,包括但不限于癌症标志物的靶向抑制。 特别地,本发明涉及作为前列腺癌的临床靶标的复发性基因融合体。
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公开(公告)号:US20110207198A1
公开(公告)日:2011-08-25
申请号:US13025290
申请日:2011-02-11
申请人: Arul M. Chinnaiyan , Sooryanaryana Lnu , Qi Cao , Irfan Asangani
发明人: Arul M. Chinnaiyan , Sooryanaryana Lnu , Qi Cao , Irfan Asangani
IPC分类号: C12N5/09 , C07H21/00 , C12N9/99 , C07K16/00 , C07D241/44
CPC分类号: C07D241/44 , C12N5/0693 , C12N2501/70
摘要: The present invention relates to agents that find use in the treatment, management, and/or study of cancer. In particular, the present invention relates to agents (e.g., small molecules, nucleic acids) that affect MMSET expression or activity.
摘要翻译: 本发明涉及可用于治疗,管理和/或研究癌症的药剂。 特别地,本发明涉及影响MMSET表达或活性的试剂(例如小分子,核酸)。
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公开(公告)号:US20110206697A1
公开(公告)日:2011-08-25
申请号:US13023694
申请日:2011-02-09
申请人: Arul M. Chinnaiyan , Bushra Ateeq , Scott Tomlins
发明人: Arul M. Chinnaiyan , Bushra Ateeq , Scott Tomlins
IPC分类号: A61K39/395 , C12N5/071 , C12N5/09 , A61P35/00 , C07K16/18
CPC分类号: C07K16/38 , A61K2039/505 , C07K2317/73 , C07K2317/76
摘要: The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to SPINK1 as a clinical target for prostate cancer.
摘要翻译: 本发明涉及用于癌症治疗的组合物和方法,包括但不限于癌症标志物的靶向抑制。 特别地,本发明涉及SPINK1作为前列腺癌的临床靶标。
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