公开(公告)号：US20060246540A1

公开(公告)日：2006-11-02

申请号：US11240891

申请日：2005-09-29

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  Austin Gurney ,  Ivar Kljavin ,  Jennie Mather ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  Austin Gurney ,  Ivar Kljavin ,  Jennie Mather ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

IPC分类号： C12P21/06 ,  C07H21/04 ,  C12N9/00 ,  C12N1/21 ,  C12N1/18 ,  C07K14/47 ,  C12N5/06 ,  C07K16/18

CPC分类号： C07K14/47 ,  A61K38/00

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050112725A1

公开(公告)日：2005-05-26

申请号：US10978255

申请日：2004-10-29

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Ivar Kljavin ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Ivar Kljavin ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

IPC分类号： G01N33/50 ,  A01K67/027 ,  A61K38/00 ,  A61K38/17 ,  A61K39/00 ,  A61K39/395 ,  A61K45/00 ,  A61P1/04 ,  A61P1/16 ,  A61P3/10 ,  A61P5/14 ,  A61P7/00 ,  A61P7/06 ,  A61P9/00 ,  A61P11/02 ,  A61P11/06 ,  A61P13/12 ,  A61P17/00 ,  A61P17/06 ,  A61P19/02 ,  A61P25/00 ,  A61P29/00 ,  A61P37/02 ,  A61P37/06 ,  A61P37/08 ,  C07H21/04 ,  C07K14/435 ,  C07K14/47 ,  C07K14/54 ,  C07K16/18 ,  C07K16/24 ,  C07K16/40 ,  C07K19/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/06 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/85 ,  C12P21/02 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/53 ,  G01N33/566 ,  G01N33/567 ,  G01N33/574

CPC分类号： G01N33/567 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/105 ,  A01K2267/03 ,  C07K14/47 ,  C12N15/8509 ,  G01N33/57484 ,  G01N2800/52

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050187382A1

公开(公告)日：2005-08-25

申请号：US10950374

申请日：2004-09-23

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Ivar Kljavin ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Sherman Fong ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Ivar Kljavin ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  Timothy Stewart ,  Daniel Tumas ,  Colin Watanabe ,  P. Williams ,  William Wood ,  Zemin Zhang

IPC分类号： C07H21/04 ,  C07K14/47 ,  C07K16/18 ,  C12N9/00

CPC分类号： C07K14/47

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20060078964A1

公开(公告)日：2006-04-13

申请号：US10216161

申请日：2002-08-09

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： C07H21/04 ,  C12P21/06 ,  C12N9/00 ,  C07K16/18 ,  C07K14/47

CPC分类号： C07K14/705

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050227342A1

公开(公告)日：2005-10-13

申请号：US10165036

申请日：2001-10-19

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： C07K14/705 ,  G01N33/53 ,  C07H21/04 ,  C12N5/06 ,  C12N9/00 ,  C12P21/02

CPC分类号： C07K14/705

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050037458A1

公开(公告)日：2005-02-17

申请号：US10805667

申请日：2004-07-23

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： C07H21/04 ,  C07K14/47 ,  C12N9/00

CPC分类号： C07K14/47 ,  G01N33/6872

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050084935A1

公开(公告)日：2005-04-21

申请号：US10897360

申请日：2004-07-21

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  G01N33/50 ,  G01N33/574 ,  G01N33/68 ,  C12P21/02 ,  C07H21/04 ,  C12N9/00

CPC分类号： G01N33/5008 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K2319/00 ,  C07K2319/30 ,  C12N2799/026 ,  C12N2799/027 ,  G01N33/5011 ,  G01N33/502 ,  G01N33/57484 ,  G01N33/68 ,  G01N33/6845

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050079577A1

公开(公告)日：2005-04-14

申请号：US10893802

申请日：2004-07-16

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07H21/04 ,  C12N9/00

CPC分类号： C07K14/47 ,  A61K38/00 ,  C07K14/4703 ,  C07K14/705 ,  C07K2319/00 ,  C07K2319/30 ,  C12N2799/026 ,  C12N2799/027

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050037463A1

公开(公告)日：2005-02-17

申请号：US10897359

申请日：2004-07-21

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07H21/04 ,  C12N9/00

CPC分类号： C07K14/4703 ,  A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C07K2319/00 ,  C07K2319/30 ,  C12N2799/026 ,  C12N2799/027

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US20050227328A1

公开(公告)日：2005-10-13

申请号：US11129762

申请日：2005-05-13

申请人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

发明人： Avi Ashkenazi ,  Kevin Baker ,  David Botstein ,  Luc Desnoyers ,  Dan Eaton ,  Napoleone Ferrara ,  Ellen Filvaroff ,  Sherman Fong ,  Wei-Qiang Gao ,  Hanspeter Gerber ,  Mary Gerritsen ,  Audrey Goddard ,  Paul Godowski ,  J. Grimaldi ,  Austin Gurney ,  Kenneth Hillan ,  Ivar Kljavin ,  Sophia Kuo ,  Mary Napier ,  James Pan ,  Nicholas Paoni ,  Margaret Roy ,  David Shelton ,  Timothy Stewart ,  Daniel Tumas ,  P. Williams ,  William Wood

IPC分类号： A61K38/00 ,  A61K39/395 ,  C07K14/47 ,  C07K14/705 ,  C07K16/28 ,  C12N5/10 ,  C12N15/12 ,  C12N15/62 ,  C12N15/63 ,  C07H21/04 ,  C07K16/18 ,  C12N9/00 ,  C12N15/09

CPC分类号： C07K14/47 ,  A61K38/00

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.