公开(公告)号：US09034077B2

公开(公告)日：2015-05-19

申请号：US14062769

申请日：2013-10-24

申请人： Aviv Amirav ,  Alexander B. Fialkov

发明人： Aviv Amirav ,  Alexander B. Fialkov

IPC分类号： G01N30/60 ,  G01N30/30 ,  G01N30/46 ,  G01N30/72

CPC分类号： G01N30/60 ,  G01N30/30 ,  G01N30/463 ,  G01N30/7206 ,  G01N2030/3061 ,  G01N2030/3069 ,  G01N2030/3076 ,  G01N2030/3084

摘要： A fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, in which a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a heated oven, which serves as a heated transferline to a flexible column that enters a resistively heated metal tube from a gas chromatograph injector and exits into a gas chromatograph detector. The resistively heated metal tube of the fast GC device has an internal diameter that is over twice the external diameter of the GC column so as to enable the insertion of several capillary GC column loops. The process of column insertion into or removal from the heated tube is aided by touching it with an ultrasound vibrating device that remarkably reduces the friction during column insertion into the metal tube heater.

摘要翻译： 一种用于获得快速气相色谱分析的快速气相色谱（GC）方法和装置，其中将毛细管气相色谱柱插入主要位于加热烘箱外部的电阻加热的金属管中，该热管用作加热的转移线到柔性柱， 从气相色谱仪进样器进入电阻加热的金属管，并进入气相色谱仪检测器。 快速GC装置的电阻加热的金属管的内径是GC柱的外径的两倍以上，以便能够插入几个毛细管GC柱回路。 通过用超声波振动装置接触来帮助柱插入或从被加热的管移除的过程，其显着地减少了柱插入金属管加热器期间的摩擦。

公开(公告)号：US20140047900A1

公开(公告)日：2014-02-20

申请号：US14062769

申请日：2013-10-24

申请人： Aviv Amirav ,  Alexander B. Fialkov

发明人： Aviv Amirav ,  Alexander B. Fialkov

IPC分类号： G01N30/60

CPC分类号： G01N30/60 ,  G01N30/30 ,  G01N30/463 ,  G01N30/7206 ,  G01N2030/3061 ,  G01N2030/3069 ,  G01N2030/3076 ,  G01N2030/3084

摘要： A fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, in which a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a heated oven, which serves as a heated transferline to a flexible column that enters a resistively heated metal tube from a gas chromatograph injector and exits into a gas chromatograph detector. The resistively heated metal tube of the fast GC device has an internal diameter that is over twice the external diameter of the GC column so as to enable the insertion of several capillary GC column loops. The process of column insertion into or removal from the heated tube is aided by touching it with an ultrasound vibrating device that remarkably reduces the friction during column insertion into the metal tube heater.

摘要翻译： 一种用于获得快速气相色谱分析的快速气相色谱（GC）方法和装置，其中将毛细管气相色谱柱插入主要位于加热烘箱外部的电阻加热的金属管中，该热管用作加热的转移线到柔性柱， 从气相色谱仪进样器进入电阻加热的金属管，并进入气相色谱仪检测器。 快速GC装置的电阻加热的金属管的内径是GC柱的外径的两倍以上，以便能够插入几个毛细管GC柱回路。 通过用超声波振动装置接触来帮助柱插入或从被加热的管移除的过程，其显着地减少了柱插入金属管加热器期间的摩擦。

公开(公告)号：US20120085148A1

公开(公告)日：2012-04-12

申请号：US12899288

申请日：2010-10-06

申请人： Aviv Amirav ,  Alexander B. Fialkov

发明人： Aviv Amirav ,  Alexander B. Fialkov

IPC分类号： G01N30/02

CPC分类号： G01N30/30 ,  G01N30/463 ,  G01N30/7206 ,  G01N2030/3061 ,  G01N2030/3069 ,  G01N2030/3076

摘要： In a fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a standard gas chromatograph oven, which may serve as a heated transfer line to a flexible column that enters the resistively heated metal tube from its injector and exits into its detector. The fast GC device enables less than one minute full range temperature programming and cooling back analysis cycle time. The fast GC according to one embodiment is combined with mass spectrometry with supersonic molecular beams for the provision of fast analysis cycle time together with highly informative mass spectral information for improved sample analysis and identification.

摘要翻译： 在用于获得快速气相色谱分析的快速气相色谱仪（GC）方法和装置中，将毛细管气相色谱柱插入主要位于标准气相色谱仪外部的电阻加热的金属管中，其可以用作加热的传输线 柔性柱，从其注射器进入电阻加热的金属管并离开其检测器。 快速GC设备可实现不到一分钟的全范围温度编程和冷却回传分析循环时间。 根据一个实施方案的快速GC与具有超音速分子束的质谱法结合，以提供快速分析周期时间以及用于改进的样品分析和鉴定的高信息性质谱信息。

公开(公告)号：US08591630B2

公开(公告)日：2013-11-26

申请号：US12899288

申请日：2010-10-06

申请人： Aviv Amirav ,  Alexander B. Fialkov

发明人： Aviv Amirav ,  Alexander B. Fialkov

IPC分类号： B01D53/02

CPC分类号： G01N30/30 ,  G01N30/463 ,  G01N30/7206 ,  G01N2030/3061 ,  G01N2030/3069 ,  G01N2030/3076

摘要： In a fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a standard gas chromatograph oven, which may serve as a heated transfer line to a flexible column that enters the resistively heated metal tube from its injector and exits into its detector. The fast GC device enables less than one minute full range temperature programming and cooling back analysis cycle time. The fast GC according to one embodiment is combined with mass spectrometry with supersonic molecular beams for the provision of fast analysis cycle time together with highly informative mass spectral information for improved sample analysis and identification.

摘要翻译： 在用于获得快速气相色谱分析的快速气相色谱仪（GC）方法和装置中，将毛细管气相色谱柱插入主要位于标准气相色谱仪外部的电阻加热的金属管中，其可以用作加热的传输线 柔性柱，从其注射器进入电阻加热的金属管并离开其检测器。 快速GC设备可实现不到一分钟的全范围温度编程和冷却回传分析循环时间。 根据一个实施方案的快速GC与具有超音速分子束的质谱法结合，以提供快速分析周期时间以及用于改进的样品分析和鉴定的高信息性质谱信息。

公开(公告)号：US6096178A

公开(公告)日：2000-08-01

申请号：US138707

申请日：1998-08-24

申请人： Aviv Amirav ,  Nitzan Tzanani

发明人： Aviv Amirav ,  Nitzan Tzanani

IPC分类号： G01N27/62 ,  G01N30/68 ,  C25B9/00 ,  C25C7/00 ,  C25D17/00

CPC分类号： G01N30/68 ,  G01N27/626

摘要： The invention provides a water electrolyzer device for generating a premixed hydrogen and oxygen gas mixture and for directing said gas mixture into a flame ionization detector, the device including a water container for performing water electrolysis; an electrode for passing electrolysis current in the water; and a water mist and vapor pressure management system for the elimination of water mist and reduction of the water relative humidity below the saturation point, the system being located between the water electrolyzer and the flame ionization detector. A method based on water electrolysis for the provision of a combustible gas mixture for the operation of a flame ionization detector is also provided.

摘要翻译： 本发明提供了一种用于产生预混氢气和氧气混合物并用于将所述气体混合物引导到火焰离子化检测器中的水电解器装置，该装置包括用于进行水电解的水容器; 用于在水中通过电解电流的电极; 以及用于消除水雾并降低水相对湿度低于饱和点的水雾和蒸汽压力管理系统，该系统位于水电解槽和火焰离子化检测器之间。 还提供了一种基于水电解用于提供用于操作火焰离子化检测器的可燃气体混合物的方法。

公开(公告)号：US5741711A

公开(公告)日：1998-04-21

申请号：US566555

申请日：1995-12-04

申请人： Aviv Amirav ,  Nitzan Tzanani

发明人： Aviv Amirav ,  Nitzan Tzanani

IPC分类号： G01N21/72 ,  G01N27/62 ,  G01N30/26 ,  G01N30/68 ,  G01N30/74 ,  G01N31/12 ,  G01N21/71

CPC分类号： G01N30/68 ,  G01N27/626

摘要： A flame based method for analyzing a sample by introducing the sample into a combustible gas mixture, igniting the combustible gas mixture to produce a flame, and detecting a characteristic of the resulting flame to determine the identity and/or concentration of one or more chemical substances in the sample, wherein the combustible gas mixture is generated by water electrolysis. The same method is also utilizable for determining the identity and/or concentration of one or more chemical compounds in the sample. A flame based detector apparatus for analyzing a sample is also described. The apparatus includes an inlet for introducing combustible gases therein, a feeder for introducing the sample into combustible gases, an ignitor for igniting the combustible gases to produce a flame, a detector for detecting a characteristic of the resulting flame for determining the identity and/or concentration of one or more chemical substances in the sample, and a water electrolyser for generating combustible gases and for directing the gases to the inlet.

摘要翻译： 一种基于火焰的方法，用于通过将样品引入可燃气体混合物中，点燃可燃气体混合物以产生火焰并检测所得火焰的特性以确定一种或多种化学物质的特性和/或浓度来分析样品 在样品中，其中可燃气体混合物通过水电解产生。 相同的方法也可用于确定样品中一种或多种化合物的身份和/或浓度。 还描述了用于分析样品的基于火焰的检测器装置。 该设备包括用于将可燃气体引入其中的入口，用于将样品引入可燃气体的进料器，用于点燃可燃气体以产生火焰的点火器，用于检测所得到的火焰的特征以确定身份和/或 样品中一种或多种化学物质的浓度，以及用于产生可燃气体并将气体引导到入口的水电解槽。

公开(公告)号：US07928370B2

公开(公告)日：2011-04-19

申请号：US12469779

申请日：2009-05-21

申请人： Aviv Amirav ,  Alexander Gordin

发明人： Aviv Amirav ,  Alexander Gordin

IPC分类号： H01J49/26 ,  B01D53/02

CPC分类号： H01J49/049

摘要： An open probe method for sample introduction into a mass spectrometer is disclosed, comprising the steps of: loading a sample holder with sample compounds to be analyzed; heating a probe oven; introducing said sample compounds in said sample holder into said heated probe oven; flowing inert gas into said heated probe oven; vaporizing said sample in said heated probe oven by the combined effect of oven temperature and inert gas flow; entraining said vaporized sample in said inert gas; and, transferring said vaporized sample in inert gas into an ion source of a mass spectrometer; wherein said heated probe oven remains open to the ambient atmosphere during sample introduction and analysis; said inert gas is flowing in said heated probe oven in two directions of a transfer line to a mass spectrometer ion source and to the oven opening; said vaporized sample in inert gas is transferred through a heated transfer line directly into the ionization chamber of an ion source of a mass spectrometer. An apparatus for this method of sample introduction is also disclosed. The primary advantage of this method and apparatus is that the heated probe oven remains open to the ambient atmosphere during sample introduction and analysis thereby enabling faster sample analysis.

摘要翻译： 公开了用于将样品引入质谱仪的开放式探针方法，其包括以下步骤：将样品保持器加载到待分析的样品化合物; 加热探头烤箱; 将所述样品保持器中的所述样品化合物引入所述加热的探针炉中 将惰性气体流入所述加热的探针烘箱; 通过烘箱温度和惰性气体流量的组合效应使所述加热的探针烘箱中的所述样品汽化; 在所述惰性气体中夹带所述蒸发的样品; 将所述蒸发的惰性气体样品转移到质谱仪的离子源中; 其中所述加热的探针烘箱在样品引入和分析期间保持对周围大气敞开; 所述惰性气体在所述加热的探针烘箱中沿传输线的两个方向流动到质谱离子源和烘箱开口; 所述汽化的惰性气体样品通过加热的输送管线直接转移到质谱仪的离子源的电离室中。 还公开了这种样品引入方法的装置。 该方法和装置的主要优点是在样品引入和分析期间，加热的探针烘箱保持对环境大气敞开，从而实现更快的样品分析。

公开(公告)号：US5686656A

公开(公告)日：1997-11-11

申请号：US607474

申请日：1996-02-27

申请人： Aviv Amirav ,  Shai Dagan

发明人： Aviv Amirav ,  Shai Dagan

IPC分类号： G01N30/02 ,  G01N30/12 ,  G01N30/16 ,  G01N30/24 ,  G01N30/72 ,  H01J49/04

CPC分类号： G01N30/12 ,  G01N2030/025 ,  G01N2030/126 ,  G01N30/24

摘要： There is provided a method for sample introduction into a gas chromatograph for performing sample analysis, in which a sample is introduced into a removable sample container, the container is placed in a sample introduction device, the device with said container is inserted into a gas chromatograph injector, and the sample is then vaporized for effecting analysis thereof by the gas chromatograph. The non-volatile residues of the sample retained in the container after vaporization and are removed with the container prior to performing the next analysis. There is also provided a method for direct sample introduction into a mass spectrometer for performing sample analysis, in which a sample is loaded into a sample container, the container with the sample is introduced into the injector of a gas chromatograph connected to a mass spectrometer through a capillary column, the injector is heated to a temperature sufficient to vaporize the sample to produce a flow of compounds which are swept to the mass spectrometer by a carrier gas, and the container is removed from the injector prior to performing the next analysis. Devices for introducing samples into a gas chromatograph for analyzing said sample are also described and claimed.

摘要翻译： 提供了将样品引入气相色谱仪进行样品分析的方法，其中将样品引入可移除的样品容器中，将容器放置在样品引入装置中，将具有所述容器的装置插入气相色谱仪 注射器，然后将样品蒸发以通过气相色谱仪进行分析。 蒸发后样品的非挥发性残留物保留在容器中，并在进行下一次分析之前用容器除去。 还提供了将样品直接引入质谱仪进行样品分析的方法，其中将样品装载到样品容器中，将具有样品的容器引入连接到质谱仪的气相色谱仪的注射器中，通过 毛细管柱，将注射器加热到足以蒸发样品的温度，以产生通过载气扫过质谱流的化合物流，并且在进行下一次分析之前从容器中取出该容器。 还将对用于将样品引入用于分析所述样品的气相色谱仪的装置进行描述和要求保护。

公开(公告)号：US4845367A

公开(公告)日：1989-07-04

申请号：US141866

申请日：1988-01-11

申请人： Aviv Amirav ,  Albert Danon

发明人： Aviv Amirav ,  Albert Danon

IPC分类号： H01J27/26

CPC分类号： H01J27/26

摘要： A method and apparatus for producing ions by surface ionization by increasing the molecular energy of the substance to be ionized to the hyperthermal energy range, and directing a beam of the substance to impinge against a solid surface disposed in a vacuum chamber. The solid surface is one e.g., clean diamond or dirty molybdenum, which is capable of inducing from the substance, e.g., an organic halide, molecular ionization or dissociative ionization of the substance, and one which does not react with the molecules or tend to neutralize the produced ions. The molecular energy includes kinetic energy gained in aerodynamic acceleration by seeding a light gas, e.g., hydrogen or helium, with molecules of the substance to be ionized, thereby producing a hyperthermal beam of 0.5-20 electron volts of the substance to be ionized.

摘要翻译： 一种用于通过将被离子化的物质的分子能量增加到超热能范围并通过物理射束撞击设置在真空室中的固体表面而通过表面电离产生离子的方法和装置。 固体表面是例如清洁的金刚石或脏的钼，其能够从物质诱导，例如有机卤化物，物质的分子电离或离解电离，以及不与分子反应或倾向于中和的物质 产生的离子。 分子能量包括通过将诸如氢或氦的轻质气体与待离子化物质的分子接合在空气动力学加速中获得的动能，由此产生待电离物质的0.5-20电子伏特的超热束。

公开(公告)号：US10790131B2

公开(公告)日：2020-09-29

申请号：US16407667

申请日：2019-05-09

申请人： Aviv Amirav

发明人： Aviv Amirav ,  Alexander B. Fialkov

IPC分类号： H01J49/16 ,  H01J49/04 ,  H01J49/26 ,  H01J27/24 ,  H01J49/10

摘要： Method for producing ions for mass spectrometry analysis, including introducing vaporized sample compounds behind a supersonic nozzle and expanding the sample compounds with a carrier gas from the supersonic nozzle into a supersonic nozzle vacuum chamber proximate thereto for vibrationally cooling the sample compounds prior to their ionization. Sample compounds are ionized by either illumination with vacuum ultra-violet photons produced by a continuously operated vacuum ultra-violet photon source or by electrons produced in a fly-through electron ionization ion source; and the ions are transferred to a mass analyzer mounted in a mass analyzer vacuum chamber to obtain mass spectra from vibrationally cold molecules. A quadrupole mass analyzer mounted may be used to obtain mass spectra with dominant molecular ions and fragment ion intensities below 3% of the molecular ion for hydrocarbons. Carrier gas flow rate may exceed 20 ml/min for vibrationally cooling the sample compounds prior to their ionization.