公开(公告)号：US20240408371A1

公开(公告)日：2024-12-12

申请号：US18809744

申请日：2024-08-20

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  James Dedig ,  Michael Spohn ,  John Haury

IPC: A61M39/10 ,  A61M39/00 ,  A61M39/24

Abstract: A fluid mixing device for mixing a first injection fluid and a second injection fluid includes a first fluid inlet, a second fluid inlet, a mixing chamber in fluid communication with the first and second fluid inlets, and an outlet port in fluid communication with the mixing chamber. The first fluid inlet is configured to conduct the first injection fluid in a first direction and has a first redirecting surface. The second fluid inlet is configured to conduct the second injection fluid in a second direction along a different axis from the first direction and has a second redirecting surface. The mixing chamber is configured to mix the first injection fluid and the second fluid together. The mixture of the first injection fluid and the second injection fluid exits the fluid mixing device via the outlet port.

公开(公告)号：US11826541B2

公开(公告)日：2023-11-28

申请号：US16621809

申请日：2018-09-12

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Barry Tucker ,  Matthew Walker ,  James Dedig ,  James Fentress ,  Joseph Ranaletta

IPC: A61M5/00 ,  A61M5/20 ,  A61M5/31 ,  A61M5/315 ,  B65B3/00 ,  B65B7/28 ,  A61M5/145 ,  A61M39/24

CPC classification number: A61M5/007 ,  A61M5/204 ,  A61M5/3134 ,  A61M5/31515 ,  B65B3/003 ,  B65B7/28 ,  A61M2005/14553 ,  A61M2005/3104 ,  A61M2005/3114 ,  A61M2039/2486 ,  A61M2039/2493 ,  A61M2205/3334 ,  A61M2209/045

Abstract: A cap for intake and delivery of a fluid from a syringe is described. The cap includes an outer cap assembly comprising a fluid inlet path and a fluid outlet path and an inner cap assembly configured for insertion into a fluid nozzle of the syringe and to provide selective fluid communication between an interior of a syringe and the fluid inlet path or the fluid outlet path. The outer cap assembly is slidable relative to the inner cap assembly between a first filling position, where the interior of the syringe is in fluid communication with the fluid inlet path, and a second delivery position, where the interior of the syringe is in fluid communication with the fluid outlet path. Syringes including the cap are also described.

公开(公告)号：US20240342368A1

公开(公告)日：2024-10-17

申请号：US18756447

申请日：2024-06-27

Applicant: Bayer HealthCare LLC

Inventor： Andrew Naples ,  Kevin Cowan ,  Michael Spohn ,  John Haury ,  Patrick Campbell ,  James Dedig ,  Randy Lee ,  John Caswell ,  Katherine MacNamee ,  James Tirone

IPC: A61M5/145 ,  A61M5/168 ,  A61M5/36

CPC classification number: A61M5/14546 ,  A61M5/16881 ,  A61M5/365

Abstract: A cassette for holding fluid path components for a fluid injector may include a body defining at least one feature for holding at least one fluid path component for the fluid injector; and a connecting member for removably connecting the body of the cassette to the fluid injector, the connecting member operatively connected to the body, wherein the connecting member comprises at least one pivotable connecting feature protruding from the body, and wherein each of the at least one pivotable connecting feature is configured for removably connecting to a corresponding connecting feature receiver on the fluid injector such that the body is pivotally movable relative to the fluid injector between a first, unlatched position and a second, latched position in which the at least one fluid path component on the body of the cassette is positioned for operative connection to a corresponding feature of the fluid injector.

公开(公告)号：US12070568B2

公开(公告)日：2024-08-27

申请号：US18324674

申请日：2023-05-26

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  James Dedig ,  Michael Spohn ,  John Haury

IPC: A61M39/10 ,  A61M39/24 ,  A61M39/00

CPC classification number: A61M39/105 ,  A61M39/24 ,  A61M2039/0027 ,  A61M2039/242

Abstract: A fluid mixing device for mixing a first injection fluid and a second injection fluid includes a first fluid inlet, a second fluid inlet, a mixing chamber in fluid communication with the first and second fluid inlets, and an outlet port in fluid communication with the mixing chamber. The first fluid inlet is configured to conduct the first injection fluid in a first direction and has a first redirecting surface. The second fluid inlet is configured to conduct the second injection fluid in a second direction along a different axis from the first direction and has a second redirecting surface. The mixing chamber is configured to mix the first injection fluid and the second fluid together. The mixture of the first injection fluid and the second injection fluid exits the fluid mixing device via the outlet port.

公开(公告)号：US20240066239A1

公开(公告)日：2024-02-29

申请号：US18504823

申请日：2023-11-08

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  James Dedig ,  Michael Spohn ,  John Haury ,  Arthur Uber

IPC: A61M5/36 ,  A61M5/00 ,  A61M5/145

CPC classification number: A61M5/365 ,  A61M5/007 ,  A61M5/14546

Abstract: An apparatus for suspending air bubbles in a fluid path of a fluid injector system includes an internal chamber having a curved interior wall defined within the housing, an inlet fluid pathway in fluid communication with the internal chamber, and an outlet fluid pathway in fluid communication with the internal chamber. The inlet fluid pathway extending into the chamber at a tangent to the curved interior wall, and the outlet fluid pathway spaced from the inlet fluid pathway such that fluid flowing into the internal chamber via the inlet fluid pathway is directed away from the outlet fluid pathway. The internal chamber is configured to create an internal fluid vortex in an injection fluid entering the internal chamber from the inlet fluid pathway, and wherein the internal fluid vortex at least temporarily suspends one or more air bubbles in the fluid in the internal vortex and delays the passage of the one or more air bubbles to the outlet fluid pathway.

公开(公告)号：US20230293874A1

公开(公告)日：2023-09-21

申请号：US18324674

申请日：2023-05-26

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  James Dedig ,  Michael Spohn ,  John Haury

IPC: A61M39/10 ,  A61M39/24

CPC classification number: A61M39/105 ,  A61M39/24 ,  A61M2039/0027

Abstract: A fluid mixing device for mixing a first injection fluid and a second injection fluid includes a first fluid inlet, a second fluid inlet, a mixing chamber in fluid communication with the first and second fluid inlets, and an outlet port in fluid communication with the mixing chamber. The first fluid inlet is configured to conduct the first injection fluid in a first direction and has a first redirecting surface. The second fluid inlet is configured to conduct the second injection fluid in a second direction along a different axis from the first direction and has a second redirecting surface. The mixing chamber is configured to mix the first injection fluid and the second fluid together. The mixture of the first injection fluid and the second injection fluid exits the fluid mixing device via the outlet port.

公开(公告)号：US11998718B2

公开(公告)日：2024-06-04

申请号：US17999592

申请日：2021-06-16

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  James Dedig ,  Shahab Taheri ,  Abhinav Srivastava ,  Barry Tucker ,  Michael Swantner ,  Christopher Capone ,  Jaroslow Wlodarczyk ,  Andrew Osan

IPC: A61M5/145 ,  A61M5/315 ,  A61M5/36

CPC classification number: A61M5/14546 ,  A61M5/31515 ,  A61M5/365 ,  A61M2005/14553

Abstract: A plunger for use with a syringe includes a plunger body defining a central longitudinal axis and having a proximal end, a distal end, and a circumferential sidewall connecting the proximal end and the distal end. The plunger further includes at least one retaining member associated with and extending proximally from the plunger body. The at least one retaining member has a first end connected to the plunger body, a second end proximal to the first end and radially and resiliently deflectable relative to the first end, and at least one catch on the second end. A fluid injector system includes a piston having a plunger engagement mechanism configured for interacting with the at least one retaining element of the plunger to releasably engage the plunger for reciprocally driving the plunger within a barrel of the syringe.

公开(公告)号：US11938093B2

公开(公告)日：2024-03-26

申请号：US17800733

申请日：2021-02-18

Applicant: BAYER HEALTHCARE LLC

Inventor： Michael Spohn ,  Kevin Cowan ,  James Dedig ,  John Haury

IPC: A61J1/20 ,  A61M5/178 ,  A61M39/10

CPC classification number: A61J1/2096 ,  A61M5/1782 ,  A61M39/1011

Abstract: A fluid path connector for a medical fluid delivery system, the fluid path connector including a first connector element comprising a body, a first lumen, a first flexible leg, and a second flexible leg, and a second connector element comprising a body defining an undercut, a second lumen, a channel defined in the body, and at least one sealing element positioned within the channel, in which the first flexible leg comprises a first flange and the second flexible leg comprises a second flange, and in which, upon engagement of the first connector element with the second connector element, the first flange and the second flange engage with the undercut of the body of the second connector element to prevent disengagement of the first connector element and the second connector element.

公开(公告)号：US20230158229A1

公开(公告)日：2023-05-25

申请号：US18094672

申请日：2023-01-09

Applicant: BAYER HEALTHCARE LLC

Inventor： Kevin Cowan ,  Michael Spohn ,  Barry Tucker ,  James Dedig ,  Gregory Johnston ,  Michael McDermott ,  David Berry ,  Adam Steege ,  Keith Lipford ,  Chet Larrow ,  Mariano Mumpwer ,  Danica Gordon

IPC: A61M5/145 ,  A61M5/00 ,  A61M5/142 ,  A61M5/24

CPC classification number: A61M5/14546 ,  A61M5/007 ,  A61M5/14216 ,  A61M5/1454 ,  A61M5/14586 ,  A61M5/2425 ,  A61M2005/14506 ,  A61M2005/14553

Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and pivotally movable about a pivot pin relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are pivotally movable about the pivot pin in a radially inward direction to engage with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.

公开(公告)号：US20220184568A1

公开(公告)日：2022-06-16

申请号：US17686929

申请日：2022-03-04

Applicant: Bayer Healthcare LLC

Inventor： Ralph Schriver ,  Andreas Maihoefer ,  James Dedig ,  Michael Spohn ,  Herbert Grubic ,  Michael Swantner ,  Adam Caruso

IPC: B01F25/431 ,  A61M5/00 ,  A61M5/168 ,  A61M39/10 ,  B01F23/45 ,  B01F25/23 ,  B01F25/00 ,  B01F25/433 ,  B01F25/452 ,  B01F25/4314 ,  B01F25/432 ,  B01F27/50 ,  B01F27/55 ,  B01F27/111 ,  B01F33/501 ,  B01F35/51

Abstract: A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described. The method includes predicting a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid with a first capacitance correction factor and a second capacitance correction factor, respectively, selecting a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection, determining a relative acceleration ratio of a first piston of the first syringe and a second piston of a second syringe based on the predicted first capacitance volume and the predicted second capacitance volume, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection, and injecting a mixture of a first medical fluid and a second medical fluid having the selected ratio with the powered injection system.