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22 条记录 (耗时 0.01 秒)

    5-nitrofuryl-2-s-triazolo-(4,3-a)-pyridine derivatives
    3.
    发明授权
    5-nitrofuryl-2-s-triazolo-(4,3-a)-pyridine derivatives 失效
    5-硝基呋喃-2-S-三唑并（4,3-A） - 吡啶衍生物

    公开(公告)号：US3597423A

    公开(公告)日：1971-08-03

    申请号：US3597423D

    申请日：1967-08-08

    申请人： BOEHRINGER MANNHEIM GMBH

    发明人： WIEDEMANN FRITZ ,  THIEL MAX ,  STACH KURT ,  VOEMEL WOLFGANG

    IPC分类号： C07D471/04 ,  C07D31/42

    CPC分类号： C07D471/04

    摘要： NOVEL COMPOUNDS USEFUL AS CHEMO-THERAPEUTIC AGENTS BECAUSE FO THEIR OUTSTANDING EFFCTIVENESS AGAINST A WIDE RANGE OF MICRO-ORGANISMS, SUCH AS, STAPHYLOCOCCUS AUREUS, ESCHERICHIA COLI, PROTEUS MIRABILIS, PSEUDOMONAS AERUGIONOSA AND STREPTOCOCCUS PYOGENES ARE DISCLOSED. THE COMPOUNDS ARE 5 - NITROFURYL - 2-S-TRIAZOLE-(4.3-A) PYRIDINE DERIVATIVES HAVING THE FOLLOWING STRUCTURAL FORMULA:

    R2-,3-R1-S-TRIAZOLO(4,3-A)PYRIDINE

    WHEREIN R1 AND R2 ARE EACH MEMBERS SELECTED FROM THE GROUP CONSITING OF HYDROGEN, HALOGEN, ALKYL, ALKOXY, NITRO, ANIMO, ACYLAMINO, CARBOXYALKYL, CARBOXAMIDO, HYDROXYMETHYL, O-ACYLATED HYDROXYMETHYL, O-ALKYLATED HYDROXYMETHYL AND

    (2-O2N-FURAN-5-YL)-(CH=CH)N-

    WHEREIN N IS 0 OR 1, WITH AT LEAST ONE OF SAID R1 AND R2 ALWAYS BEING

    (2-O2N-FURAN-5-YL)-(CH=CH)

    2-amino-adenosine derivatives
    8.
    发明授权
    2-amino-adenosine derivatives 失效
    2-氨基腺苷衍生物

    公开(公告)号：US3590029A

    公开(公告)日：1971-06-29

    申请号：US3590029D

    申请日：1968-08-22

    申请人： BOEHRINGER MANNHEIM GMBH

    发明人： KOCH KLAUS ,  FAULAND ERICH ,  STACH KURT ,  THIEL MAX ,  SCHAUMANN WOLFGANG ,  DIETMANN KARL

    IPC分类号： C07H19/16 ,  C07D51/54

    CPC分类号： C07H19/16

    摘要： NOVEL 2-AMINO-ADENOSINE DRIVATIVES CHARACTERIZED BY CARDIAC AND CIRCULATORY ACTIVITY AND BY THEIR HIGH CORONARY SPECIFICITY HAVING THE FOLLOWING STRUCTURAL FORMULA:

    2-NH2,6-(R1-N(-R2)-),9-(3,4,5-TRI(HO-)-2-TETRAHYDRO-

    PYRANYL)-9H-PURINE

    WHEREIN R1 IS HYDROGEN, A SUBSTITUTED OR UNSUBSTITUDED, SATURATED OR UNSATURATED, STRAIGHT OR BRANCHED CHAIN ALIPHATIC HYDROCARBON RADICAL, WHEREIN SAID SUBSTITUENT IS AT LEAST ONE OF AMINO, ALKYLAMINO, DIALKYLAMINO, ACYLAMINO, ALKOXY, ACYLOXY, HYDROXY, MERCAPTO, ALKYLMERCAPTO, CARBOXY, CARBOXY ALKYL OR CARBOXAMIDO AND R2 IS A SATURATED OR UNSATURATED CYCLOALKYL RADICAL WHICH CAN CARRY ENDOALKYLENE RADICALS OR ANNELLATED, SATURATED OR UNSATURATED CYCLIC ALIPHATIC HYDROCARBON RADICALS, WHEREIN SAID SUBA-X-3, WHEREIN A IS A SUBSTITUTED OR UNSUBSTITUTED, SATURATED OR UNSATURATED, STRAIGHT OR BRANCHED CHAIN, OR CYCLIC ALIPHATIC HYDROCARBON RADICAL, WHEREIN SAID SUBSTITUENT IS AT LEAST ONE OF HYDROXY, ACYLOXY, CARBOXY AND ARYL RADICALS, X IS A VALENCY BOND, AN OXYGEN OR SULFUR ATOM, ALKYLATED IMINO OR ACYLATED IMINO, AND B IS A SUBSTITUTED OR UNSUBSTITUTED ALKYL, ALKENYL, ARYL, FURYL, PYRIDYL, INDOLYL OR IMIDAZOLYL RADICAL, WHEREIN SAID SUBSTITUENT IS AT LEAST ONE OF HALOGEN, ALKYL, HALOALKYL, ALKOXY, ARYLOXY, ACYLOXY, HYDROXY, MERCAPTO, ALKYLMERCAPTO, NITRO, CARBOXY, CARBOXYLALKYL AND METHYLSULFONYLAMINO RADICALS.