公开(公告)号：US20250090174A1

公开(公告)日：2025-03-20

申请号：US18888648

申请日：2024-09-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Steven L Kangas ,  Edward Kopesky ,  Amod Shridhar Modak ,  Victoria Szlag

IPC: A61B17/12

Abstract: Medical devices as wells as methods for making and using medical devices are disclosed. An example medical device may include a left atrial appendage device. The occlusive medical device includes an expandable frame configured to shift between a first configuration and an expanded configuration and a fabric disposed along at least a portion of the expandable frame. A drug eluting coating is disposed on the fabric, the drug eluting coating including a pharmaceutically active component dispersed within a polymeric carrier.

公开(公告)号：US20140141048A1

公开(公告)日：2014-05-22

申请号：US14084821

申请日：2013-11-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： David Rolf ,  Steven L Kangas

IPC: A61L29/16

CPC classification number: A61L29/16 ,  A61L29/085 ,  A61L29/14 ,  A61L29/145 ,  A61L29/148 ,  A61L31/10 ,  A61L31/14 ,  A61L31/145 ,  A61L31/148 ,  A61L2300/236 ,  A61L2400/10 ,  A61L2420/02 ,  C08L5/10

Abstract: According to one aspect of the disclosure, medical devices are provided which have a negatively charged surface and a lubricous hydrophilic coating comprising a sulf(on)ated species disposed on the negatively charged surface. In various embodiments, the sulf(on)ated species is ionically crosslinked with itself and with the negatively charged species by a multivalent cationic species. In other aspects, medical devices are provided which have a polymeric surface and a lubricous hydrophilic layer comprising a covalently crosslinked sulf(on)ated species disposed on the surface. Still other aspects of the invention pertain to methods of forming such devices and methods of using such devices.

Abstract translation: 根据本公开的一个方面，提供具有带负电荷的表面的医疗装置和包含设置在带负电的表面上的磺基（物质）物质的润滑亲水涂层。 在各种实施方案中，硫酸（物质）与其自身和带负电荷的物质通过多价阳离子物质离子交联。 在其他方面，提供了具有聚合物表面和包含布置在表面上的共价交联的磺基（物质）物质的润滑亲水层的医疗装置。 本发明的其它方面涉及形成这种装置的方法和使用这种装置的方法。