公开(公告)号：US20240342348A1

公开(公告)日：2024-10-17

申请号：US18632758

申请日：2024-04-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Thomas John Herbst ,  Edward Kopesky ,  Steven L. Kangas ,  Hongxia Zeng ,  Aaron Cooper Foss

IPC: A61L33/00 ,  A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61L33/0041 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/204 ,  A61L2300/216 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/61 ,  A61L2300/622 ,  A61L2300/802 ,  A61L2420/02 ,  A61L2420/08

Abstract: A medical device may be coated with a therapeutic composition that includes a direct oral anticoagulant. An illustrative drug coating composition may comprise an excipient including polylactic acid (PLA), poly(lactic-co-glycolic acid) (PLGA), or poly(vinylidene fluoride)-co-hexafluoropropylene (PVDF-HFP) and a direct oral anticoagulant (DOAC). The illustrative drug coating may be applied to an outer surface of a medical device.

公开(公告)号：US20240115270A1

公开(公告)日：2024-04-11

申请号：US18490400

申请日：2023-10-19

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Steven L. Kangas ,  Edward Kopesky ,  Yen-Lane Chen

IPC: A61B17/12 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/5377

CPC classification number: A61B17/12177 ,  A61B17/12122 ,  A61B17/12172 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/5377 ,  A61B2017/00526

Abstract: A device for permanent placement across an atrial appendage ostium in a patient includes a support structure having a contracted delivery configuration and an expanded deployed configuration defining a radially enlarged portion to permanently engage an interior wall of the atrial appendage, a membrane attached to the support structure and configured to extend across the ostium of the atrial appendage when the support structure is in the expanded deployed configuration, and a polymer coating disposed on at least one of the support structure and the membrane, the polymer coating including a direct oral anticoagulant (DOAC) dispersed in a polymer.

公开(公告)号：US20250090174A1

公开(公告)日：2025-03-20

申请号：US18888648

申请日：2024-09-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Steven L Kangas ,  Edward Kopesky ,  Amod Shridhar Modak ,  Victoria Szlag

IPC: A61B17/12

Abstract: Medical devices as wells as methods for making and using medical devices are disclosed. An example medical device may include a left atrial appendage device. The occlusive medical device includes an expandable frame configured to shift between a first configuration and an expanded configuration and a fabric disposed along at least a portion of the expandable frame. A drug eluting coating is disposed on the fabric, the drug eluting coating including a pharmaceutically active component dispersed within a polymeric carrier.

公开(公告)号：US20230011767A1

公开(公告)日：2023-01-12

申请号：US17860848

申请日：2022-07-08

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Steven L. Kangas ,  Edward Kopesky ,  Yen-Lane Chen

IPC: A61B17/12 ,  A61K31/4545 ,  A61K31/5377 ,  A61K31/444

Abstract: A device for permanent placement across an atrial appendage ostium in a patient includes a support structure having a contracted delivery configuration and an expanded deployed configuration defining a radially enlarged portion to permanently engage an interior wall of the atrial appendage, a membrane attached to the support structure and configured to extend across the ostium of the atrial appendage when the support structure is in the expanded deployed configuration, and a polymer coating disposed on at least one of the support structure and the membrane, the polymer coating including a direct oral anticoagulant (DOAC) dispersed in a polymer.

公开(公告)号：US11484320B2

公开(公告)日：2022-11-01

申请号：US17125747

申请日：2020-12-17

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Steven L. Kangas ,  Edward Kopesky ,  Yen-Lane Chen

IPC: A61B17/12 ,  A61L33/00

Abstract: Medical devices as wells as methods for making and using medical devices are disclosed. An example medical device may include a left atrial appendage device. The left atrial appendage device may include an expandable frame configured to shift between a first configuration and an expanded configuration. A fabric mesh may be disposed along at least a portion of the expandable frame. An anti-thrombogenic coating may be disposed along the fabric mesh.