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公开(公告)号：US11382859B1
公开(公告)日：2022-07-12
申请号：US16787186
申请日：2020-02-11
申请人： BRAHM HOLDINGS, LLC
发明人： Timothy R. Brahm
摘要： A cosmetic composition for the repair and remodeling of the human skin is provided. The cosmetic composition includes a therapeutically effective amount of human birth tissue material and a suitable carrier composition. Methods of treating human skin with the cosmetic composition, methods of reducing the appearance of a skin condition arising from aging and a corresponding kit are also provided.
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公开(公告)号：US10722539B2
公开(公告)日：2020-07-28
申请号：US15223831
申请日：2016-07-29
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
IPC分类号： A61K35/34 , A61K35/36 , A61K35/35 , A61K9/70 , A61K47/42 , A61K45/06 , A61K35/28 , A61K38/39 , A61K9/00 , A61K45/00
摘要： Wound treatment compositions obtained from cadaveric tissues are provided. Methods of processing such tissues to form wound treatment compositions are provided. Methods of treating a wound are also provided.
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公开(公告)号：US11160665B2
公开(公告)日：2021-11-02
申请号：US16434638
申请日：2019-06-07
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
摘要： A surgical balloon composed of an aseptically recovered umbilical cord vessel is provided. Methods of preparing a balloon and methods of using the same are also provided.
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公开(公告)号：US10058632B1
公开(公告)日：2018-08-28
申请号：US15614950
申请日：2017-06-06
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
CPC分类号： A61L27/54 , A61K33/06 , A61K35/50 , A61K35/51 , A61L27/3604 , A61L27/40 , A61L27/50 , A61L27/60 , A61L2300/102 , A61L2300/104 , A61L2400/06 , A61L2400/12 , A61L2430/02 , A61L2430/34
摘要： A placental construct is provided. The placental construct includes a therapeutically effective amount of human birth tissue material and a nanoparticle composition. Methods of treatment with the placental construct and a corresponding kit are also provided.
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5.发明授权公开(公告)号：US11547731B2
公开(公告)日：2023-01-10
申请号：US16026569
申请日：2018-07-03
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
IPC分类号： A61K35/50
摘要： Methods of treating inflammation, pain or both inflammation and pain in a subject are provided. The method includes the step of administering a human birth tissue material composition on or within an affected site of a body. The methods are particularly suitable for treatment of inflammation, pain or both inflammation and pain arising from a viral infection.
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公开(公告)号：US10583219B1
公开(公告)日：2020-03-10
申请号：US15391944
申请日：2016-12-28
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
摘要： A multilayer bioabsorbable construct is provided that includes at least one top layer, at least one chorion membrane layer, at least one basement layer, and at least one support layer between the chorion membrane layer and basement layer. Various therapeutic uses of the multilayer bioabsorbable construct are also provided.
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公开(公告)号：US10687865B2
公开(公告)日：2020-06-23
申请号：US15852349
申请日：2017-12-22
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm , Patrick Curlee
摘要： Provided herein is a spinal graft that fuses to and stabilizes the spine upon placement thereby helping to prevent spinal stenosis recurrence and eliminating pain associated with an unstable spine. The graft may be coated with a human birth tissue composition. Also provided herein are methods of stabilizing the spine after decompression surgery.
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公开(公告)号：US10596203B1
公开(公告)日：2020-03-24
申请号：US14879543
申请日：2015-10-09
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm , Jerry Chang
摘要： Customized, three-dimensionally printed constructs useful for promoting tissue repair and methods of preparing the same are provided.
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公开(公告)号：US10201573B1
公开(公告)日：2019-02-12
申请号：US14923837
申请日：2015-10-27
申请人： Brahm Holdings, LLC
发明人： Timothy R. Brahm
摘要： Methods of treating vascular damage caused by a cerebral vascular accident in a subject are provided. The method includes the step of administering an effective amount of a human birth tissue material composition to a damaged site in a brain.
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