公开(公告)号：US11382859B1

公开(公告)日：2022-07-12

申请号：US16787186

申请日：2020-02-11

申请人： BRAHM HOLDINGS, LLC

发明人： Timothy R. Brahm

IPC分类号： A61K8/98 ,  A61K35/51 ,  A61K35/50 ,  A61Q19/08 ,  A61Q19/00 ,  A61K35/48

摘要： A cosmetic composition for the repair and remodeling of the human skin is provided. The cosmetic composition includes a therapeutically effective amount of human birth tissue material and a suitable carrier composition. Methods of treating human skin with the cosmetic composition, methods of reducing the appearance of a skin condition arising from aging and a corresponding kit are also provided.

公开(公告)号：US20210369777A1

公开(公告)日：2021-12-02

申请号：US17331832

申请日：2021-05-27

申请人： BRAHM HOLDINGS, LLC

发明人： Timothy R. BRAHM

IPC分类号： A61K35/17 ,  A61K38/19 ,  A61K38/21 ,  A61K45/06

摘要： A therapeutic composition is provided. The therapeutic composition is particularly useful in the treatment of various symptoms arising from immune responses to pathogenic infections. The therapeutic compositions includes an acellular mammalian birth tissue material composition and a stem cell composition. Methods of treatment are also provided.

公开(公告)号：US10722539B2

公开(公告)日：2020-07-28

申请号：US15223831

申请日：2016-07-29

申请人： Brahm Holdings, LLC

发明人： Timothy R. Brahm

IPC分类号： A61K35/34 ,  A61K35/36 ,  A61K35/35 ,  A61K9/70 ,  A61K47/42 ,  A61K45/06 ,  A61K35/28 ,  A61K38/39 ,  A61K9/00 ,  A61K45/00

摘要： Wound treatment compositions obtained from cadaveric tissues are provided. Methods of processing such tissues to form wound treatment compositions are provided. Methods of treating a wound are also provided.

公开(公告)号：US20190314550A1

公开(公告)日：2019-10-17

申请号：US16385240

申请日：2019-04-16

申请人： Brahm Holdings, LLC

发明人： Timothy R. BRAHM

IPC分类号： A61L27/36 ,  A61L27/54

摘要： A substitute composition is provided that includes at least one cadaveric material and at least one liquid component which, upon introduction to the cadaveric material, causes the cadaveric material to expand and become flowable. Methods for stabilizing a vertebral space are also provided.

公开(公告)号：US20190314422A1

公开(公告)日：2019-10-17

申请号：US16385226

申请日：2019-04-16

申请人： Brahm Holdings, LLC

发明人： Timothy R. BRAHM

IPC分类号： A61K35/50 ,  A61K35/51 ,  A61K38/20 ,  A61K39/00

摘要： The present disclosure generally relates to constructs, formulations and methods for the treatment of various types of cancer. The constructs, formulations and methods as provided herein are particularly useful for the treatment of various tumorigenic cancers.

公开(公告)号：US20180311285A1

公开(公告)日：2018-11-01

申请号：US16026569

申请日：2018-07-03

申请人： Brahm Holdings, LLC

发明人： Timothy R. BRAHM

IPC分类号： A61K35/50

CPC分类号： A61K35/50

摘要： Methods of treating inflammation, pain or both inflammation and pain in a subject are provided. The method includes the step of administering a human birth tissue material composition on or within an affected site of a body. The methods are particularly suitable for treatment of inflammation, pain or both inflammation and pain arising from a viral infection.

公开(公告)号：US11160665B2

公开(公告)日：2021-11-02

申请号：US16434638

申请日：2019-06-07

申请人： Brahm Holdings, LLC

发明人： Timothy R. Brahm

IPC分类号： A61B17/88 ,  A61F2/44 ,  A61F2/46 ,  A61B17/70 ,  A61B17/56 ,  A61L27/36 ,  A61B17/32

摘要： A surgical balloon composed of an aseptically recovered umbilical cord vessel is provided. Methods of preparing a balloon and methods of using the same are also provided.

公开(公告)号：US10058632B1

公开(公告)日：2018-08-28

申请号：US15614950

申请日：2017-06-06

申请人： Brahm Holdings, LLC

发明人： Timothy R. Brahm

IPC分类号： A61L27/54 ,  A61K35/50 ,  A61K33/06 ,  A61L27/36 ,  A61L27/40

CPC分类号： A61L27/54 ,  A61K33/06 ,  A61K35/50 ,  A61K35/51 ,  A61L27/3604 ,  A61L27/40 ,  A61L27/50 ,  A61L27/60 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2400/06 ,  A61L2400/12 ,  A61L2430/02 ,  A61L2430/34

摘要： A placental construct is provided. The placental construct includes a therapeutically effective amount of human birth tissue material and a nanoparticle composition. Methods of treatment with the placental construct and a corresponding kit are also provided.

公开(公告)号：US11547731B2

公开(公告)日：2023-01-10

申请号：US16026569

申请日：2018-07-03

申请人： Brahm Holdings, LLC

发明人： Timothy R. Brahm

IPC分类号： A61K35/50

摘要： Methods of treating inflammation, pain or both inflammation and pain in a subject are provided. The method includes the step of administering a human birth tissue material composition on or within an affected site of a body. The methods are particularly suitable for treatment of inflammation, pain or both inflammation and pain arising from a viral infection.

公开(公告)号：US20210322480A1

公开(公告)日：2021-10-21

申请号：US17235166

申请日：2021-04-20

申请人： BRAHM HOLDINGS, LLC

发明人： Timothy R. BRAHM

IPC分类号： A61K35/19 ,  A61K35/16 ,  C07K16/10

摘要： An antiviral composition is provided. The antiviral composition includes a platelet-rich plasma composition. Methods of treatment and initiating passive immunity for viral infections are also provided.