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    BARRIER LAYER FOR GLUCOSE SENSOR
    2.
    发明申请
    BARRIER LAYER FOR GLUCOSE SENSOR 有权
    用于葡萄糖传感器的障碍层

    公开(公告)号：US20130040404A1

    公开(公告)日：2013-02-14

    申请号：US13578893

    申请日：2011-02-15

    申请人： Barry Colin Crane ,  William Paterson ,  Bruce Culbert

    发明人： Barry Colin Crane ,  William Paterson ,  Bruce Culbert

    IPC分类号： G01N21/64 ,  B23P11/00

    CPC分类号： G01N33/66 ,  A61B5/14532 ,  A61B5/1459 ,  B01D63/00 ,  B01L2200/027 ,  G01N21/7703 ,  G01N2021/772 ,  G01N2021/775 ,  G01N2021/7786 ,  Y10T29/49826

    摘要： An optical glucose sensor comprising: a sensing region comprising a boronic acid receptor for binding to glucose and a fluorophore associated with said receptor; an optical waveguide for directing incident light onto the sensing region; and a hydrophilic, polymeric, glucose-permeable barrier layer which is provided on at least a part of the sensing region; wherein the sensor is adapted so that glucose enters the sensing region of the sensor through said barrier layer.

    摘要翻译： 一种光学葡萄糖传感器，包括：包含用于结合葡萄糖的硼酸受体和与所述受体相关联的荧光团的感测区域; 用于将入射光引导到感测区域上的光波导; 以及设置在所述感测区域的至少一部分上的亲水性，聚合物，葡萄糖可渗透阻挡层; 其中所述传感器适于使得葡萄糖通过所述阻挡层进入所述传感器的感测区域。

    Sensor Calibration
    4.
    发明申请
    Sensor Calibration 有权
    传感器校准

    公开(公告)号：US20120240656A1

    公开(公告)日：2012-09-27

    申请号：US13430066

    申请日：2012-03-26

    申请人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    发明人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    IPC分类号： G01N33/00

    CPC分类号： G01N35/00693 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/1495 ,  G01N27/3274

    摘要： A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.

    摘要翻译： 传感器套件，包括用于检测分析物的传感器，传感器外壳和校准室。 校准室包括含有第一校准溶液的第一隔室和含有待检测分析物源的第二隔室。 分隔材料位于第一和第二隔室之间，使得它们能够在破碎或除去分隔材料时混合。 还可以提供含有其他进一步来源的进一步的隔室。 校准可以通过（a）读取第一校准溶液的分析物浓度来进行，（b）通过破碎或除去分割材料混合第一和第二隔室的内容物，以及（c）读取 所得混合物的分析物浓度。 如果需要，步骤（b）和（c）可以重复进一步的隔室以提供进一步的读数。

    Sensor calibration
    5.
    发明授权
    Sensor calibration 有权
    传感器校准

    公开(公告)号：US09097687B2

    公开(公告)日：2015-08-04

    申请号：US13430066

    申请日：2012-03-26

    申请人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    发明人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    IPC分类号： G01N35/00 ,  A61B5/1459 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145

    CPC分类号： G01N35/00693 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/1495 ,  G01N27/3274

    摘要： A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.

    摘要翻译： 一种传感器套件，包括用于检测分析物的传感器，传感器外壳和校准室。 校准室包括含有第一校准溶液的第一隔室和含有待检测分析物源的第二隔室。 分隔材料位于第一和第二隔室之间，使得它们能够在破碎或除去分隔材料时混合。 还可以提供含有其他进一步来源的进一步的隔室。 校准可以通过（a）读取第一校准溶液的分析物浓度来进行，（b）通过破碎或除去分割材料混合第一和第二隔室的内容物，以及（c）读取 所得混合物的分析物浓度。 如果需要，步骤（b）和（c）可以重复进一步的隔室以提供进一步的读数。

    Sensor calibration
    6.
    发明授权
    Sensor calibration 有权
    传感器校准

    公开(公告)号：US08141409B2

    公开(公告)日：2012-03-27

    申请号：US12308865

    申请日：2007-06-28

    申请人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    发明人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    IPC分类号： G01N1/38

    CPC分类号： G01N35/00693 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/1495 ,  G01N27/3274

    摘要： A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.

    摘要翻译： 传感器套件，包括用于检测分析物的传感器，传感器外壳和校准室。 校准室包括含有第一校准溶液的第一隔室和含有待检测分析物源的第二隔室。 分隔材料位于第一和第二隔室之间，使得它们能够在破碎或除去分隔材料时混合。 还可以提供含有其他进一步来源的进一步的隔室。 校准可以通过（a）读取第一校准溶液的分析物浓度来进行，（b）通过破碎或除去分割材料混合第一和第二隔室的内容物，以及（c）读取 所得混合物的分析物浓度。 如果需要，步骤（b）和（c）可以重复进一步的隔室以提供进一步的读数。

    Sensor Calibration
    7.
    发明申请
    Sensor Calibration 有权
    传感器校准

    公开(公告)号：US20090277242A1

    公开(公告)日：2009-11-12

    申请号：US12308865

    申请日：2007-06-28

    申请人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    发明人： Barry Crane ,  Ian Francis ,  Robert Perkins ,  William Paterson

    IPC分类号： G01N33/487

    CPC分类号： G01N35/00693 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/1495 ,  G01N27/3274

    摘要： A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.

    摘要翻译： 传感器套件，包括用于检测分析物的传感器，传感器外壳和校准室。 校准室包括含有第一校准溶液的第一隔室和含有待检测分析物源的第二隔室。 分隔材料位于第一和第二隔室之间，使得它们能够在破碎或除去分隔材料时混合。 还可以提供含有其他进一步来源的进一步的隔室。 校准可以通过（a）读取第一校准溶液的分析物浓度来进行，（b）通过破碎或除去分割材料混合第一和第二隔室的内容物，以及（c）读取 所得混合物的分析物浓度。 如果需要，步骤（b）和（c）可以重复进一步的隔室以提供进一步的读数。

    Method and system for continuity testing of medical electrodes
    9.
    发明申请
    Method and system for continuity testing of medical electrodes 失效
    医用电极连续性检测方法及系统

    公开(公告)号：US20050182398A1

    公开(公告)日：2005-08-18

    申请号：US11051075

    申请日：2005-02-04

    申请人： William Paterson

    发明人： William Paterson

    IPC分类号： A61N1/08 ,  A61B18/12 ,  A61B18/18 ,  G01R31/02

    CPC分类号： G01R31/026 ,  A61B18/1206 ,  A61B18/1233 ,  A61B2018/146

    摘要： An electrosurgical generator is provided which includes a continuity test circuit assembly for testing electrical continuity through an electrode of an electrosurgical instrument. The continuity test circuit assembly includes a test power source providing electrical test energy to a first conductor which is in electrical communication with the electrode and the electrosurgical generator and to at least one second conductor which is coupled to the first conductor for providing a path for current to flow between the first conductor and the at least one second conductor for establishing a test path through which the test energy flows between the first conductor and at least one conductor of the at least one second conductor. The continuity test circuit assembly further includes energy detection circuitry positioned along the test path for detecting the flow of the test energy through the test path for determining electrical continuity through the electrode.

    摘要翻译： 提供一种电外科发生器，其包括用于通过电外科器械的电极测试电连续性的连续性测试电路组件。 连续性测试电路组件包括向与电极和​​电外科发生器电连通的第一导体提供电测试能量的测试电源以及耦合到第一导体的至少一个第二导体，以提供用于电流的路径 以在所述第一导体和所述至少一个第二导体之间流动，以建立所述测试能量在所述第一导体和所述至少一个第二导体的至少一个导体之间流动的测试路径。 连续性测试电路组件还包括沿着测试路径定位的能量检测电路，用于检测通过测试路径的测试能量的流动，以确定通过电极的电连续性。

    SENSING APPARATUS
    10.
    发明申请
    SENSING APPARATUS 审中-公开
    感应装置

    公开(公告)号：US20100305413A1

    公开(公告)日：2010-12-02

    申请号：US12672586

    申请日：2008-08-05

    申请人： William Paterson

    发明人： William Paterson

    IPC分类号： A61B5/145 ,  B29C35/08

    CPC分类号： A61B5/14542 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14539 ,  A61M25/005 ,  A61M25/007

    摘要： A process for preparing a tube for insertion into the human or animal body, said process comprising: (a) providing a hollow tube comprising a first material and a second material, the first material being in the form of a coil or a tubular mesh, and the second material coating the first material in order to form a continuous substantially impermeable outer wall of the hollow tube; (b) selectively removing a portion of said second material in order to generate at least one opening in a region of the outer wall, while retaining the first material in said region.

    摘要翻译： 一种用于制备用于插入人或动物体内的管的方法，所述方法包括：（a）提供包含第一材料和第二材料的中空管，所述第一材料为线圈或管状网状， 并且所述第二材料涂覆所述第一材料以形成所述中空管的连续的基本上不可渗透的外壁; （b）选择性地去除所述第二材料的一部分以便在外壁的区域中产生至少一个开口，同时将第一材料保持在所述区域中。