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    METHOD AND APPARATUS FOR DETECTING A LIPOPHILIC ANALYTE OF INTEREST IN A SAMPLE
    1.
    发明申请
    METHOD AND APPARATUS FOR DETECTING A LIPOPHILIC ANALYTE OF INTEREST IN A SAMPLE 有权
    用于检测样品中嗜酸性分析物的方法和装置

    公开(公告)号：US20120267259A1

    公开(公告)日：2012-10-25

    申请号：US13499732

    申请日：2010-10-11

    申请人： David M. Pettigrew ,  Stuart P. Hendry ,  Peter G. Laitenberger

    发明人： David M. Pettigrew ,  Stuart P. Hendry ,  Peter G. Laitenberger

    IPC分类号： G01N27/26

    CPC分类号： G01N33/48714

    摘要： Disclosed is a method and apparatus for detecting the concentration of a lipophilic analyte of interest in a complex sample matrix. The method comprises extracting the analyte of interest from said sample into an organic solvent comprising a dissolved electrolyte; providing a free radical species, preferably a free oxygen radical species, in said organic solvent; reacting the Canalyte of interest with said free radical species; and performing a measurement to detect the concentration of the free radical-reacted analyte reaction product.

    摘要翻译： 公开了用于检测复合样品基质中感兴趣的亲脂性分析物的浓度的方法和装置。 该方法包括将目标分析物从所述样品提取到包含溶解的电解质的有机溶剂中; 在所述有机溶剂中提供自由基物质，优选游离氧自由基物质; 使所关心的加利利人与所述自由基物种反应; 并进行测定以检测自由基反应的分析物反应产物的浓度。

    Sensor
    2.
    发明申请
    Sensor 审中-公开
    传感器

    公开(公告)号：US20100163431A1

    公开(公告)日：2010-07-01

    申请号：US12095625

    申请日：2006-12-01

    申请人： Peter G. Laitenberger ,  Stuart P. Hendry

    发明人： Peter G. Laitenberger ,  Stuart P. Hendry

    IPC分类号： G01N33/543

    CPC分类号： G01N27/3274

    摘要： This invention relates to a sensor for detecting an analyte in the presence of at least one interferent in a fluid sample. The sensor comprises a substrate, a channel disposed on the substrate, at least one transducer disposed in the channel, and a filter for selectively absorbing the analyte in preference to the at least one interferent. The filter is arranged in the channel remotely from the at least one transducer and the channel defines a flow path for the fluid sample such that the fluid sample contacts a first transducer to generate a first signal, followed by the filter, followed by the first transducer or a second transducer to generate a second signal.

    摘要翻译： 本发明涉及用于在存在流体样品中的至少一种干扰物的情况下检测分析物的传感器。 传感器包括衬底，设置在衬底上的通道，设置在通道中的至少一个换能器，以及用于选择性地吸收分析物优先于至少一个干扰物的过滤器。 所述过滤器布置在所述通道中远离所述至少一个换能器并且所述通道限定用于所述流体样品的流动路径，使得所述流体样品接触第一换能器以产生第一信号，随后是所述滤波器，随后是所述第一换能器 或第二传感器以产生第二信号。

    Method for assembling package for an active medical device
    3.
    发明授权
    Method for assembling package for an active medical device 失效
    用于组装主动医疗装置的包装的方法

    公开(公告)号：US5357732A

    公开(公告)日：1994-10-25

    申请号：US64615

    申请日：1993-05-20

    申请人： David R. Markle ,  Stuart P. Hendry ,  Michael P. Irvine

    发明人： David R. Markle ,  Stuart P. Hendry ,  Michael P. Irvine

    IPC分类号： B65D81/24 ,  A61B5/00 ,  A61B19/02 ,  B65B31/02 ,  B65B5/08 ,  B65B61/00

    CPC分类号： A61B5/145 ,  A61B50/30 ,  A61B2050/005 ,  A61B50/33 ,  Y10S439/912

    摘要： A method for assembling a package for an active medical device which comprises making an opening in a wall of a recess shaped to receive the device, placing a gasket against the wall and about a band mounted through a flat portion of the wall, inserting the band through the opening so the gasket is flush against the wall, installing an outer part about the band to hold the gasket against the wall to form a sterile barrier, and placing a lid over the recess to contain the device within a sterile field.

    摘要翻译： 一种用于组装用于主动医疗装置的包装件的方法，包括在形状为接收所述装置的凹部的壁中形成开口，将衬垫放置在壁上并围绕安装在壁的平坦部分上的带上，将带 通过开口使得垫圈与壁齐平，围绕带安装外部部分以将垫圈保持抵靠壁以形成无菌屏障，并将盖放置在凹部上以将该装置容纳在无菌区域内。

    Method for manufacturing an electro chemical sensor
    8.
    发明授权
    Method for manufacturing an electro chemical sensor 失效
    电化学传感器的制造方法

    公开(公告)号：US5310471A

    公开(公告)日：1994-05-10

    申请号：US67649

    申请日：1993-05-26

    申请人： David R. Markle ,  Stuart P. Hendry

    发明人： David R. Markle ,  Stuart P. Hendry

    IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  G01N27/404 ,  G01N27/26

    CPC分类号： A61B5/14542 ,  A61B5/1473 ,  Y10T29/4911 ,  Y10T29/49117 ,  Y10T29/49172 ,  Y10T29/49176

    摘要： A method for manufacturing an electrochemical sensor which comprises folding into a "U" shape an exposed, uninsulated portion of an elongate, insulated conductor to form an anode having an exposed, uninsulated distal end surface, positioning the end surface of the anode to face the exposed, uninsulated distal end surface of an elongate insulated conductor forming a cathode, placing the anode and facing cathode within a tube defined by a gas permeable membrane, filling the tube with an electrolyte and sealing the distal end of the tube.

    摘要翻译： 一种用于制造电化学传感器的方法，其包括将细长的绝缘导体的暴露的未绝缘部分折叠成“U”形，以形成具有暴露的未绝缘的远端表面的阳极，将阳极的端表面定位成面对 形成阴极的细长绝缘导体的暴露的未绝缘的远端表面，将阳极和面对的阴极放置在由透气膜限定的管内，用电解液填充管并密封管的远端。

    Package for an active medical device
    9.
    发明授权
    Package for an active medical device 失效
    活动医疗器械的包装

    公开(公告)号：US5246109A

    公开(公告)日：1993-09-21

    申请号：US888569

    申请日：1992-05-22

    申请人： David R. Markle ,  Stuart P. Hendry ,  Michael P. Irvine

    发明人： David R. Markle ,  Stuart P. Hendry ,  Michael P. Irvine

    IPC分类号： B65D81/24 ,  A61B5/00 ,  A61B19/02

    CPC分类号： A61B5/145 ,  A61B50/30 ,  A61B2050/005 ,  A61B50/33 ,  Y10S439/912

    摘要： A package for an active medical device has a film member pocket recess. The member has a planar flange about the recess and a flat wall with an opening. A lid attaches to the flange. Outer and inner parts of a junction conjugate in the opening to seal and insure sterility. Test means on the inner part test means include a transparent window in a central web to permit optical signal transmission and electrical signals pass through a plurality of spaced apart electrically conductive pins about the web to distally couple the device and test linkage. An inner part band with a brim thereabout fits through the opening so the brim faces the wall. An outer part collar with a rim thereabout conjugates with the band that extends through the opening and the rim abuts in tight facing relation the wall. The brim and band support a resilient gasket for compression between the wall and the brim when threads on the band mate with threads on the collar. An assembly method entails making an opening in the package wall, placing a gasket against the brim, inserting the band through the opening and installing the collar on the band to form a sterile barrier with threads. A test method entails inserting the device in the recess, attaching the device to the junction, applying energy to the connection from outside and receiving modified energy from the device.

    Method and apparatus for detecting a lipophilic analyte of interest in a sample
    10.
    发明授权
    Method and apparatus for detecting a lipophilic analyte of interest in a sample 有权
    用于检测样品中感兴趣的亲脂性分析物的方法和装置

    公开(公告)号：US08784641B2

    公开(公告)日：2014-07-22

    申请号：US13499732

    申请日：2010-10-11

    申请人： David M. Pettigrew ,  Stuart P. Hendry ,  Peter G. Laitenberger

    发明人： David M. Pettigrew ,  Stuart P. Hendry ,  Peter G. Laitenberger

    IPC分类号： G01N27/49

    CPC分类号： G01N33/48714

    摘要： Disclosed is a method and apparatus for detecting the concentration of a lipophilic analyte of interest in a complex sample matrix. The method comprises extracting the analyte of interest from said sample into an organic solvent comprising a dissolved electrolyte; providing a free radical species, preferably a free oxygen radical species, in said organic solvent; reacting the analyte of interest with said free radical species; and performing a measurement to detect the concentration of the free radical-reacted analyte reaction product.

    摘要翻译： 公开了用于检测复合样品基质中感兴趣的亲脂性分析物的浓度的方法和装置。 该方法包括将目标分析物从所述样品提取到包含溶解的电解质的有机溶剂中; 在所述有机溶剂中提供自由基物质，优选游离氧自由基物质; 使感兴趣的分析物与所述自由基物质反应; 并进行测定以检测自由基反应的分析物反应产物的浓度。