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12 条记录 (耗时 0.021 秒)

    SLEEVE WITH CONFIGURABLE ELECTRODES FOR FUNCTIONAL ELECTRICAL STIMULATION AND/OR ELECTROMYOGRAPHY
    3.
    发明申请
    SLEEVE WITH CONFIGURABLE ELECTRODES FOR FUNCTIONAL ELECTRICAL STIMULATION AND/OR ELECTROMYOGRAPHY 有权

    公开(公告)号：US20220031245A1

    公开(公告)日：2022-02-03

    申请号：US17389437

    申请日：2021-07-30

    申请人： Battelle Memorial Institute

    发明人： Herbert S. Bresler

    IPC分类号： A61B5/00 ,  A61B5/256 ,  A61B5/389 ,  A61N1/04

    摘要： A device for functional electrical stimulation (FES), neuromuscular electrical stimulation (NMES), and/or electromyography (EMG) readout includes a sleeve sized and shaped to be worn on a human arm and comprising an inner sleeve and an outer sleeve. The inner sleeve has openings formed therein, and has an exposed side positioned to contact skin and an opposite backside facing the outer sleeve. Electrode strips each comprise a linear circuit board on which a row of electrodes is mounted. The electrode strips are detachably and selectively mountable to the inner sleeve in a plurality of different orientations. The electrode strips are mountable on the inner sleeve with the linear circuit boards disposed on the backside of the inner sleeve between the inner sleeve and the outer sleeve and the electrodes passing through the openings of the inner sleeve so as to be positioned to contact skin.

    DRUG SUSCEPTIBILITY USING RARE CELL DETECTION SYSTEM
    4.
    发明申请
    DRUG SUSCEPTIBILITY USING RARE CELL DETECTION SYSTEM 审中-公开
    使用稀有细胞检测系统的药物不耐症

    公开(公告)号：US20130084579A1

    公开(公告)日：2013-04-04

    申请号：US13622740

    申请日：2012-09-19

    申请人： Battelle Memorial Institute

    发明人： Herbert S. Bresler ,  Kevin M. Taylor ,  John S. Laudo ,  Thomas D. Haubert

    IPC分类号： G01N33/94

    CPC分类号： G01N33/94 ,  B01L3/50215 ,  G01N33/5011 ,  G01N33/582

    摘要： Methods for determining the efficacy of a given drug for a specific patient with cancer in vitro prior to, or after, the initiation of treatment of the patient are disclosed. Blood from the cancer patient is separated into an assay test tube and a control test tube. The blood in the assay test tube is exposed to a cancer drug. The two test tubes are then visually examined and compared to determine the effect of the cancer drug on cancer cells, other rare cells in the blood, or on normal constituents of the blood of a cancer patient.

    摘要翻译： 公开了在开始治疗患者之前或之后确定给定药物对特定癌症患者的功效的方法。 将来自癌症患者的血液分离成测定试管和对照试管。 测定试管中的血液暴露于癌症药物。 然后目视检查并比较两个试管，以确定癌症药物对癌细胞，血液中的其它罕见细胞或癌症患者血液正常成分的影响。

    Methods for tailoring the refractive index of lenses
    6.
    发明授权
    Methods for tailoring the refractive index of lenses 有权

    公开(公告)号：US10254562B2

    公开(公告)日：2019-04-09

    申请号：US15068396

    申请日：2016-03-11

    申请人： Battelle Memorial Institute

    发明人： Herbert S. Bresler ,  Erik Edwards ,  Amy M. Heintz ,  John S. Laudo ,  Alexander C. Morrow ,  Steven M. Risser

    IPC分类号： G02C7/04 ,  G02C7/02 ,  A61F2/16 ,  G02B1/04

    摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

    METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES
    8.
    发明申请
    METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES 审中-公开
    用于定制镜片折射率的方法

    公开(公告)号：US20160195735A1

    公开(公告)日：2016-07-07

    申请号：US15068396

    申请日：2016-03-11

    申请人： Battelle Memorial Institute

    发明人： Herbert S. Bresler ,  Erik Edwards ,  Amy M. Heintz ,  John S. Laudo ,  Alexander C. Morrow ,  Steven M. Risser

    IPC分类号： G02C7/02 ,  G02C7/04 ,  G02B1/04

    CPC分类号： G02C7/022 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1659 ,  A61F2002/16965 ,  G02B1/043 ,  G02C7/04

    摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

    摘要翻译： 公开了用于改变诸如人工晶状体的透镜的功率的方法和装置。 在一种方法中，透镜包含含有可交联侧基的单一聚合物基质，其中当交联时聚合物基体的体积增加。 镜头不含有游离单体。 当暴露于紫外线辐射时，交联使得透镜的暴露部分体积增加，导致折射率增加。 在另一种方法中，透镜包含含有可光漂白的发色团的聚合物基质。 在紫外线照射下，光漂白导致曝光部分的折射率降低，透镜厚度没有变化。 这些方法避免了等待发生扩散以改变透镜形状的需要，并且避免了第二次暴露于辐射以锁定透镜变化的需要。