Abstract:
Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.
Abstract:
Light is transmitted from a light source through or from a separator of a battery cell and received by one or more light detectors. The light that is normally transmitted through the separator is scattered, absorbed, wavelength-shifted or otherwise distorted by an impending fault in the vicinity of or within the separator. The change in light due to the impending fault is measured by a detector and a signal from the detector is processed to identify the impending fault so that a warning can be generated indicative of the impending fault. In particular, one or both of the light source and detector are enclosed within a battery cell housing and receive power from the electrodes of the battery cell.
Abstract:
Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a polymer matrix containing photobleachable chromophores and a radical scavenger dispersed in the polymer matrix. In another method, a sensitizer is added to the lens. In yet another method, the lens comprises a chromophore that has a chromophore having at least two isomers. In yet another method, the lens comprises photobleachable multiphoton chromophores.
Abstract:
The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.
Abstract:
Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.
Abstract:
A novel method of forming thin films of carbon nanotubes (CNTs) is described. In this method, carbon nanotubes are dispersed in a superacid solution and laid down on a substrate to form a conductive and transparent CNT network film. The superacid, in its deprotonated state, is an anion that has a permanent dipole moment. The superacid solution may be a pure superacid or have additional solvent. Preferably, the superacid solution does not contain an oxidizing agent. Novel, highly conductive and transparent CNT network films are also described.
Abstract:
The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.
Abstract:
In an approach to measuring a magnetic field of a sample, a system includes an optical fiber comprising a first end and a second end, the optical fiber having a core; and a nitrogen vacancy (NV) diamond sensor; where the first end of the optical fiber is configured to receive excitation light from an optical excitation source; and the NV diamond sensor is coupled to the second end of the optical fiber with an optical matching material, the optical matching material configured to optically match the NV diamond sensor to the core of the optical fiber.
Abstract:
Disclosed are methods of separating solute from solvent using a photoactive extractant. The photoactive extractant can be switched between two states by exposure to light. This can change the affinity of the photoactive extractant for either the solute or the solvent, causing absorption of the solute or solvent. The photoactive extractant can then be separated from the fluid stream containing the solute or solvent. The absorbed solute or solvent is then separated from the photoactive extractant. The photoactive extractant is a photoisomer. Applications for these methods include desalination, water purification, and metal extraction.
Abstract:
The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.