公开(公告)号：US07920669B2

公开(公告)日：2011-04-05

申请号：US12010920

申请日：2008-01-31

申请人： Bernhard Krauβ ,  Fernando Vega-Higuera

发明人： Bernhard Krauβ ,  Fernando Vega-Higuera

IPC分类号： A61B6/00

CPC分类号： A61B6/482 ,  A61B6/032 ,  A61B8/483 ,  G06T15/08

摘要： Methods, apparatuses and computer readable mediums for generating a volume visualization image based on multi-energy computed tomography data are provided. In one method, an image is rendered based on a multi-dimensional graphical representation of the computed tomography data. The computed tomography data includes at least two different energy image data sets and the multi-dimensional graphical representation represents intensity values of each of the at least two different energy image data sets.

摘要翻译： 提供了用于基于多能计算机断层摄影数据生成体视觉图像的方法，装置和计算机可读介质。 在一种方法中，基于计算机断层摄影数据的多维图形表示来渲染图像。 计算机断层摄影数据包括至少两个不同的能量图像数据集，并且所述多维图形表示表示所述至少两个不同能量图像数据集中的每一个的强度值。

公开(公告)号：US20130155064A1

公开(公告)日：2013-06-20

申请号：US13713603

申请日：2012-12-13

申请人： Sasa Grbic ,  Razvan Ioan Ionasec ,  Fernando Vega-Higuera ,  Dominik Bernhardt ,  Dorin Comaniciu

发明人： Sasa Grbic ,  Razvan Ioan Ionasec ,  Fernando Vega-Higuera ,  Dominik Bernhardt ,  Dorin Comaniciu

IPC分类号： A61B5/055 ,  G06T17/00

CPC分类号： A61B5/055 ,  G06T7/11 ,  G06T7/149 ,  G06T7/162 ,  G06T17/00 ,  G06T2207/20081 ,  G06T2207/20156 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and system for automatic aortic valve calcification evaluation is disclosed. A patient-specific aortic valve model in a 3D medical image volume, such as a 3D computed tomography (CT) volume. Calcifications in a region of the 3D medical image volume defined based on the aortic valve model. A 2D calcification plot is generated that shows locations of the segmented calcifications relative to aortic valve leaflets of the patient-specific aortic valve model. The 2D calcification plot can be used for assessing the suitability of a patient for a Transcatheter Aortic Valve Replacement (TAVI) procedure, as well as risk assessment, positioning of an aortic valve implant, and selection of a type of aortic valve implant.

摘要翻译： 公开了一种自动主动脉瓣钙化评价方法和系统。 3D医学图像体积中的患者特异性主动脉瓣模型，例如3D计算机断层摄影（CT）体积。 基于主动脉瓣模型定义的3D医学图像体积的区域中的钙化。 生成2D钙化曲线，其显示相对于患者特异性主动脉瓣模型的主动脉瓣叶的分段钙化的位置。 2D钙化图可用于评估患者对于经导管主动脉瓣置换（TAVI）程序的适用性，以及风险评估，主动脉瓣植入物的定位和主动脉瓣植入物的选择。

公开(公告)号：US20120323545A1

公开(公告)日：2012-12-20

申请号：US13523925

申请日：2012-06-15

申请人： Peter Aulbach ,  Dominik Bernhardt ,  Fernando Vega-Higuera

发明人： Peter Aulbach ,  Dominik Bernhardt ,  Fernando Vega-Higuera

IPC分类号： G06G7/48

CPC分类号： A61B6/5223 ,  A61B6/504 ,  A61B34/10 ,  A61B2034/108 ,  A61F2/24

摘要： A device for planning a transcatheter aortic valve implantation is disclosed. The device includes a segmentation module for segmenting the aorta ascendens with the aorta annulus, the aortic valves and the coronary ostia as well as the left ventricle; a determination module, which determines on the basis of the segmented data the aorta annulus plane and from this one or more angiography projections for setting an angiography device, with which the aorta annulus and the coronary ostia are able to be detected in the optimum manner for positioning the transcatheter heart valve; and an output module that outputs this information. The proposed device supports the user in the planning of a transcatheter aortic valve implantation.

摘要翻译： 公开了一种用于规划经导管主动脉瓣植入的装置。 该装置包括用于将主动脉上端与主动脉环，主动脉瓣和冠状动脉口以及左心室分割的分割模块; 确定模块，其基于所述分段数据确定所述主动脉环空平面，并且根据所述一个或多个血管造影投影来确定用于设置血管造影装置的分割数据，所述主动脉环和所述冠状动脉口能够以最佳方式被检测到 定位经导管心脏瓣膜; 以及输出该信息的输出模块。 所提出的装置支持用户规划经导管主动脉瓣植入。

公开(公告)号：US20100260400A1

公开(公告)日：2010-10-14

申请号：US12729267

申请日：2010-03-23

申请人： Dominik Bernhardt ,  Jörg Hausleiter ,  Carsten Thierfelder ,  Johann Uebler ,  Fernando Vega-Higuera

发明人： Dominik Bernhardt ,  Jörg Hausleiter ,  Carsten Thierfelder ,  Johann Uebler ,  Fernando Vega-Higuera

IPC分类号： G06T7/00

CPC分类号： A61B6/481 ,  A61B5/02007 ,  A61B6/032 ,  A61B6/504 ,  G06T7/0012 ,  G06T7/11 ,  G06T7/136 ,  G06T7/70 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and a data-processing system are disclosed for determining the proportion of calcium in coronary arteries using image data from CT angiography. In at least one embodiment of the method, anatomical landmarks are detected in the image data in the region of the heart and coronary arteries are segmented taking into account the detected landmarks. Regions with an increased HU value compared to a contrast agent surroundings are segmented in the segmented coronary arteries. A proportion of calcium respectively is calculated from the segmented regions for one or more of the segmented coronary arteries. At least the last two steps are carried out fully automatically by a data-processing system. Weighting factors for the individual regions are used when calculating the proportion of calcium, which weighting factors depend on both the threshold for segmenting the respective region and the volume of said region. The method and the data-processing system of at least one embodiment allow the dose exposure of the patient to be reduced and reduce the time expenditure of the user for determining the proportion of calcium.

摘要翻译： 公开了一种使用来自CT血管造影术的图像数据来确定冠状动脉中钙的比例的方法和数据处理系统。 在该方法的至少一个实施例中，在心脏区域中的图像数据中检测解剖标志，并且考虑到检测到的界标来分割冠状动脉。 在分割冠状动脉中分割具有与造影剂周围环境相比增加的HU值的区域。 对于一个或多个分割冠状动脉的分割区域分别计算一部分钙。 至少最后两个步骤由数据处理系统完全自动执行。 当计算钙的比例时，使用各个区域的权重因子，该加权因子取决于分割各个区域的阈值和所述区域的体积。 至少一个实施方案的方法和数据处理系统允许减少患者的剂量暴露并减少用户确定钙的比例的时间支出。

公开(公告)号：US20080317318A1

公开(公告)日：2008-12-25

申请号：US12213744

申请日：2008-06-24

申请人： Michael Scheuering ,  Fernando Vega-Higuera

发明人： Michael Scheuering ,  Fernando Vega-Higuera

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B6/466 ,  A61B6/503 ,  A61B6/5223 ,  G06T7/0012 ,  G06T7/10 ,  G06T15/08 ,  G06T2207/10081 ,  G06T2207/20224 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and a workstation are disclosed for visualizing a three-dimensional image data record having a multiplicity of voxels of a heart of a patient, recorded with the aid of an x-ray CT examination carried out with contrast agent present in the bloodstream. In at least one embodiment, the method includes saving the CT image data record including a multiplicity of voxels defined by absorption values, determining the voxels associated with the chamber of the heart by segmenting the chambers of the heart filled with blood containing the contrast agent, removing the image information from the voxels associated with the chambers of the heart, calculating a two-dimensional virtual projection from the remaining CT image data record, and displaying the virtual two-dimensional projection.

摘要翻译： 公开了一种方法和工作站，用于通过利用存在于血流中的造影剂进行的X射线CT检查来记录具有患者心脏的多个体素的三维图像数据记录。 在至少一个实施例中，该方法包括保存包括由吸收值定义的多个体素的CT图像数据记录，通过分割填充有含有造影剂的血液的心脏室来确定与心脏腔室相关联的体素， 从与心脏室相关联的体素去除图像信息，从剩余CT图像数据记录计算二维虚拟投影，以及显示虚拟二维投影。

公开(公告)号：US20080069458A1

公开(公告)日：2008-03-20

申请号：US11857491

申请日：2007-09-19

申请人： Fernando Vega-Higuera ,  Klaus Engel

发明人： Fernando Vega-Higuera ,  Klaus Engel

IPC分类号： G06K9/36

CPC分类号： G06T15/08 ,  G06T2200/16

摘要： In a client/server-based image archiving, image retrieval and image rendering system and method for storage, retrieval and graphical visualization of multi-dimensional digital image data such as assessment of medical image data, the detail depth level of volume data received via a data transfer network, to be shown in graphical form, is adjustable by the compressed volume data of subjects to be presented being stored with a highest-possible resolution (predetermined by an imaging system) in a databank administered by a server and directly accessibly only by this server. Although the client/server-based image archiving, image retrieval and image rendering system is able to offer volume data with this highest possible resolution to any point of the system at the request of a screen client, volume data are transferred to a screen client in a compressed form only up to a specific, spatially-variable, region-specific, or subject-specific detail depth level and are presented at the requesting screen client in graphical form. Complicated image rendering and image post-processing algorithms are implemented by the server.

摘要翻译： 在基于客户端/服务器的图像存档，图像检索和图像渲染系统以及用于存储，检索和图形化可视化多维数字图像数据的方法中，例如医学图像数据的评估，经由 以图形形式显示的数据传输网络可以通过由服务器管理的数据库中以最高可能的分辨率（由成像系统预定）存储的要被呈现的被摄体的压缩音量数据进行调节，并且仅通过 这个服务器。 虽然基于客户端/服务器的图像归档，图像检索和图像渲染系统能够根据屏幕客户端的要求向系统的任何点提供具有最高可能分辨率的卷数据，但是卷数据被传送到屏幕客户端 压缩形式只能达到特定的，空间上可变的，区域特定的或特定于细节的细节深度级别，并以图形形式呈现在请求屏幕客户端。 复杂的图像渲染和图像后处理算法由服务器实现。

公开(公告)号：US09730609B2

公开(公告)日：2017-08-15

申请号：US13713603

申请日：2012-12-13

申请人： Sasa Grbic ,  Razvan Ioan Ionasec ,  Fernando Vega-Higuera ,  Dominik Bernhardt ,  Dorin Comaniciu

发明人： Sasa Grbic ,  Razvan Ioan Ionasec ,  Fernando Vega-Higuera ,  Dominik Bernhardt ,  Dorin Comaniciu

IPC分类号： A61B5/055 ,  G06T17/00 ,  G06T7/11 ,  G06T7/149 ,  G06T7/162

CPC分类号： A61B5/055 ,  G06T7/11 ,  G06T7/149 ,  G06T7/162 ,  G06T17/00 ,  G06T2207/20081 ,  G06T2207/20156 ,  G06T2207/30048 ,  G06T2207/30101

摘要： A method and system for automatic aortic valve calcification evaluation is disclosed. A patient-specific aortic valve model in a 3D medical image volume, such as a 3D computed tomography (CT) volume. Calcifications in a region of the 3D medical image volume defined based on the aortic valve model. A 2D calcification plot is generated that shows locations of the segmented calcifications relative to aortic valve leaflets of the patient-specific aortic valve model. The 2D calcification plot can be used for assessing the suitability of a patient for a Transcatheter Aortic Valve Replacement (TAVI) procedure, as well as risk assessment, positioning of an aortic valve implant, and selection of a type of aortic valve implant.

公开(公告)号：US09042619B2

公开(公告)日：2015-05-26

申请号：US13233220

申请日：2011-09-15

申请人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Shaohua Kevin Zhou ,  Dorin Comaniciu

发明人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Shaohua Kevin Zhou ,  Dorin Comaniciu

IPC分类号： G06K9/00 ,  G06K9/62 ,  G06K9/34 ,  G06T7/00

CPC分类号： G06T7/0081 ,  G06T7/11 ,  G06T7/12 ,  G06T2207/10072 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06T2207/30172

摘要： A method and system for detection of native and bypass coronary ostia in a 3D volume, such as a CT volume, is disclosed. Native coronary ostia are detected by detecting a bounding box defining locations of a left native coronary ostium and a right native coronary ostium in the 3D volume using marginal space learning (MSL), and locally refining the locations of the left native coronary ostium and the right native coronary ostium using a trained native coronary ostium detector. Bypass coronary ostia are detected by segmenting an ascending aorta surface mesh in the 3D volume, generating a search region of a plurality of mesh points on the ascending aorta surface mesh based on a distribution of annotated bypass coronary ostia in a plurality of training volumes, and detecting the bypass coronary ostia by searching the plurality of mesh points in the search region.

摘要翻译： 公开了用于检测3D体积中的天然和旁路冠状动脉口腔的方法和系统，例如CT体积。 通过使用边缘空间学习（MSL）检测在3D体积中定义左天然冠状动脉口和右天然冠状动脉口的位置的边界框来检测本地冠状动脉，并且局部改善左天然冠状动脉口和右侧的位置 使用训练有素的本地冠状动脉口腔检测器进行本地冠状动脉口。 通过分割3D体积中的上升主动脉表面网格来检测旁路冠状动脉口腔，基于多个训练体积中注释旁路冠状动脉口腔的分布，生成升主动脉表面网格上的多个网格点的搜索区域，以及 通过搜索搜索区域中的多个网格点来检测旁路冠状动脉口。

公开(公告)号：US08675943B2

公开(公告)日：2014-03-18

申请号：US13295217

申请日：2011-11-14

申请人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Dorin Comaniciu

发明人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Dorin Comaniciu

IPC分类号： G06K9/00

CPC分类号： G06T7/149 ,  G06T7/11 ,  G06T2207/10081 ,  G06T2207/20124 ,  G06T2207/30048

摘要： A method and system for isolating the heart in a 3D volume, such as a cardiac CT volume, for patients with coronary artery bypasses is disclosed. An initial heart isolation mask is extracted from a 3D volume, such as a cardiac CT volume. The aortic root and ascending aorta are segmented in the 3D volume, resulting in an aorta mesh. The aorta mesh is expanded to include bypass coronary arteries. An expanded heart isolation mask is generated by combining the initial heart isolation mask with an expanded aorta mask defined by the expanded aorta mesh.

摘要翻译： 公开了一种用于分离冠状动脉旁路患者的3D体积（例如心脏CT体积）中的心脏的方法和系统。 从3D体积（例如心脏CT体积）提取初始心脏隔离掩模。 主动脉根部和升主动脉在3D体积中分段，导致主动脉网。 主动脉网扩张包括旁路冠状动脉。 通过将初始心脏隔离掩模与由扩张的主动脉网所定义的扩张主动脉掩膜组合来产生扩张的心脏隔离掩模。

公开(公告)号：US20120134564A1

公开(公告)日：2012-05-31

申请号：US13295217

申请日：2011-11-14

申请人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Dorin Comaniciu

发明人： Yefeng Zheng ,  Fernando Vega-Higuera ,  Dorin Comaniciu

IPC分类号： G06K9/00

CPC分类号： G06T7/149 ,  G06T7/11 ,  G06T2207/10081 ,  G06T2207/20124 ,  G06T2207/30048

摘要： A method and system for isolating the heart in a 3D volume, such as a cardiac CT volume, for patients with coronary artery bypasses is disclosed. An initial heart isolation mask is extracted from a 3D volume, such as a cardiac CT volume. The aortic root and ascending aorta are segmented in the 3D volume, resulting in an aorta mesh. The aorta mesh is expanded to include bypass coronary arteries. An expanded heart isolation mask is generated by combining the initial heart isolation mask with an expanded aorta mask defined by the expanded aorta mesh.

摘要翻译： 公开了一种用于分离冠状动脉旁路患者的3D体积（例如心脏CT体积）中的心脏的方法和系统。 从3D体积（例如心脏CT体积）提取初始心脏隔离掩模。 主动脉根部和升主动脉在3D体积中分段，导致主动脉网。 主动脉网扩张包括旁路冠状动脉。 通过将初始心脏隔离掩模与由扩张的主动脉网所定义的扩张主动脉掩膜组合来产生扩张的心脏隔离掩模。