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1.发明申请Method for visualizing a three-dimensional image data record from an x-ray CT examination and workstation for carrying out the method 有权用于从X射线CT检查和工作站可视化三维图像数据记录的方法用于执行该方法公开(公告)号：US20080317318A1
公开(公告)日：2008-12-25
申请号：US12213744
申请日：2008-06-24
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/466 , A61B6/503 , A61B6/5223 , G06T7/0012 , G06T7/10 , G06T15/08 , G06T2207/10081 , G06T2207/20224 , G06T2207/30048 , G06T2207/30101
摘要： A method and a workstation are disclosed for visualizing a three-dimensional image data record having a multiplicity of voxels of a heart of a patient, recorded with the aid of an x-ray CT examination carried out with contrast agent present in the bloodstream. In at least one embodiment, the method includes saving the CT image data record including a multiplicity of voxels defined by absorption values, determining the voxels associated with the chamber of the heart by segmenting the chambers of the heart filled with blood containing the contrast agent, removing the image information from the voxels associated with the chambers of the heart, calculating a two-dimensional virtual projection from the remaining CT image data record, and displaying the virtual two-dimensional projection.
摘要翻译： 公开了一种方法和工作站，用于通过利用存在于血流中的造影剂进行的X射线CT检查来记录具有患者心脏的多个体素的三维图像数据记录。 在至少一个实施例中，该方法包括保存包括由吸收值定义的多个体素的CT图像数据记录，通过分割填充有含有造影剂的血液的心脏室来确定与心脏腔室相关联的体素， 从与心脏室相关联的体素去除图像信息，从剩余CT图像数据记录计算二维虚拟投影，以及显示虚拟二维投影。
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2.发明授权Device and computed tomography scanner for determining and visualizing the perfusion of the myocardial muscle 有权用于确定和可视化心肌灌注的装置和计算机断层扫描仪公开(公告)号：US08831320B2
公开(公告)日：2014-09-09
申请号：US13293172
申请日：2011-11-10
CPC分类号： G06F19/12 , A61B6/03 , A61B6/032 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06F17/18 , G06F19/00 , G06T7/0012 , G06T2207/10076 , G06T2207/10081 , G06T2207/30048 , G06T2207/30104 , G16H50/50
摘要： A device is disclosed for determining and visualizing the perfusion of the myocardial muscle with the aid of static CCTA images. In at least one embodiment, the device includes a segmentation unit for segmenting the coronary blood vessels and the left myocardial muscle from a CCTA image of the heart; a first simulation unit for simulating the blood flow through the coronary blood vessels; and a second simulation unit by which the local perfusion of the myocardial muscle is determined on the basis of the ascertained blood flow into different regions of the myocardial muscle. The perfusion of the different regions of the myocardial muscle is visualized in a schematized image on a visualization unit. By virtue of the proposed device it is possible to dispense with further imaging examinations after the performance of a CCTA scan, thereby relieving the pressure both on the part of the physician and on the part of the patient.
摘要翻译： 公开了一种借助于静态CCTA图像来确定和可视化心肌肌灌注的装置。 在至少一个实施例中，该装置包括用于从心脏的CCTA图像分割冠状动脉血管和左心肌的分割单元; 用于模拟通过冠状血管的血流的第一模拟单元; 以及第二模拟单元，通过该第二模拟单元，基于确定的进入心肌的不同区域的血液流量来确定心肌的局部灌注。 在可视化单元上的示意图像中可视化心肌的不同区域的灌注。 凭借所提出的装置，可以在执行CCTA扫描之后免除进一步的成像检查，从而减轻了医师和患者部分的压力。
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3.发明授权Method for visualizing a three-dimensional image data record from an x-ray CT examination and workstation for carrying out the method 有权用于从X射线CT检查和工作站可视化三维图像数据记录的方法用于执行该方法公开(公告)号：US08254653B2
公开(公告)日：2012-08-28
申请号：US12213744
申请日：2008-06-24
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/466 , A61B6/503 , A61B6/5223 , G06T7/0012 , G06T7/10 , G06T15/08 , G06T2207/10081 , G06T2207/20224 , G06T2207/30048 , G06T2207/30101
摘要： A method and a workstation are disclosed for visualizing a three-dimensional image data record having a multiplicity of voxels of a heart of a patient, recorded with the aid of an x-ray CT examination carried out with contrast agent present in the bloodstream. In at least one embodiment, the method includes saving the CT image data record including a multiplicity of voxels defined by absorption values, determining the voxels associated with the chamber of the heart by segmenting the chambers of the heart filled with blood containing the contrast agent, removing the image information from the voxels associated with the chambers of the heart, calculating a two-dimensional virtual projection from the remaining CT image data record, and displaying the virtual two-dimensional projection.
摘要翻译： 公开了一种方法和工作站，用于通过利用存在于血流中的造影剂进行的X射线CT检查来记录具有患者心脏的多个体素的三维图像数据记录。 在至少一个实施例中，该方法包括保存包括由吸收值定义的多个体素的CT图像数据记录，通过分割填充有含有造影剂的血液的心脏室来确定与心脏腔室相关联的体素， 从与心脏室相关联的体素去除图像信息，从剩余CT图像数据记录计算二维虚拟投影，以及显示虚拟二维投影。
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4.发明申请Device And Computed Tomography Scanner For Determining And Visualizing The Perfusion Of The Myocardial Muscle 有权装置和计算机断层扫描仪用于确定和可视化心肌肌灌注公开(公告)号：US20120121151A1
公开(公告)日：2012-05-17
申请号：US13293172
申请日：2011-11-10
IPC分类号： G06K9/00
CPC分类号： G06F19/12 , A61B6/03 , A61B6/032 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06F17/18 , G06F19/00 , G06T7/0012 , G06T2207/10076 , G06T2207/10081 , G06T2207/30048 , G06T2207/30104 , G16H50/50
摘要： A device is disclosed for determining and visualizing the perfusion of the myocardial muscle with the aid of static CCTA images. In at least one embodiment, the device includes a segmentation unit for segmenting the coronary blood vessels and the left myocardial muscle from a CCTA image of the heart; a first simulation unit for simulating the blood flow through the coronary blood vessels; and a second simulation unit by which the local perfusion of the myocardial muscle is determined on the basis of the ascertained blood flow into different regions of the myocardial muscle. The perfusion of the different regions of the myocardial muscle is visualized in a schematized image on a visualization unit. By virtue of the proposed device it is possible to dispense with further imaging examinations after the performance of a CCTA scan, thereby relieving the pressure both on the part of the physician and on the part of the patient.
摘要翻译： 公开了一种借助于静态CCTA图像来确定和可视化心肌肌灌注的装置。 在至少一个实施例中，该装置包括用于从心脏的CCTA图像分割冠状动脉血管和左心肌的分割单元; 用于模拟通过冠状血管的血流的第一模拟单元; 以及第二模拟单元，通过该第二模拟单元，基于确定的进入心肌的不同区域的血液流量来确定心肌的局部灌注。 在可视化单元上的示意图像中可视化心肌的不同区域的灌注。 凭借所提出的装置，可以在执行CCTA扫描之后免除进一步的成像检查，从而减轻了医师和患者部分的压力。
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5.发明申请Method and System for Non-Invasive Functional Assessment of Coronary Artery Stenosis 审中-公开冠状动脉狭窄无创功能评估方法与系统公开(公告)号：US20140058715A1
公开(公告)日：2014-02-27
申请号：US14070810
申请日：2013-11-04
申请人： Puneet Sharma , Lucian Mihai Itu , Ali Kamen , Bogdan Georgescu , Xudong Zheng , Huseyin Tek , Dorin Comaniciu , Dominik Bernhardt , Fernando Vega-Higuera , Michael Scheuering
发明人： Puneet Sharma , Lucian Mihai Itu , Ali Kamen , Bogdan Georgescu , Xudong Zheng , Huseyin Tek , Dorin Comaniciu , Dominik Bernhardt , Fernando Vega-Higuera , Michael Scheuering
IPC分类号： G06F19/00
CPC分类号： G16B5/00 , A61B5/02007 , A61B5/1128 , A61B6/032 , A61B6/503 , A61B6/5217 , A61B2576/023 , G16H50/50
摘要： A method and system for non-invasive assessment of coronary artery stenosis is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient acquired during rest state. Patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Patient-specific rest state boundary conditions of the model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Hyperemic blood flow and pressure across at least one stenosis region of the coronary arteries are simulated using the model of coronary circulation and the patient-specific hyperemic boundary conditions. Fractional flow reserve (FFR) is calculated for the at least one stenosis region based on the simulated hyperemic blood flow and pressure.
摘要翻译： 公开了冠状动脉狭窄非侵入性评估的方法和系统。 从休息状态下获得的患者的医学图像数据中提取冠状动脉的患者特异性解剖学测量。 基于患者特异性解剖学测量和静息患者的非侵入性临床测量，计算代表冠状动脉的冠状动脉循环模型的患者特异性休息状态边界条件。 基于患者特异性解剖学测量和静息患者的非侵入性临床测量，计算代表冠状动脉的冠状动脉循环模型的患者特异性休息状态边界条件。 使用冠状动脉循环模型和患者特异性充血边界条件模拟冠状动脉至少一个狭窄区域的血流量和压力。 基于模拟的充血血流量和压力计算至少一个狭窄区域的分数流量储备（FFR）。
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6.发明申请Method and System for Non-Invasive Functional Assessment of Coronary Artery Stenosis 审中-公开冠状动脉狭窄无创功能评估方法与系统公开(公告)号：US20130246034A1
公开(公告)日：2013-09-19
申请号：US13794113
申请日：2013-03-11
申请人： Puneet Sharma , Lucian Mihai Itu , Ali Kamen , Bogdan Georgescu , Xudong Zheng , Huseyin Tek , Dorin Comaniciu , Dominik Bernhardt , Fernando Vega-Higuera , Michael Scheuering
发明人： Puneet Sharma , Lucian Mihai Itu , Ali Kamen , Bogdan Georgescu , Xudong Zheng , Huseyin Tek , Dorin Comaniciu , Dominik Bernhardt , Fernando Vega-Higuera , Michael Scheuering
IPC分类号： G06F19/12
CPC分类号： G16B5/00 , A61B5/02007 , A61B5/1128 , A61B6/032 , A61B6/503 , A61B6/5217 , A61B2576/023 , G16H50/50
摘要： A method and system for non-invasive assessment of coronary artery stenosis is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient acquired during rest state. Patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Patient-specific rest state boundary conditions of the model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest. Hyperemic blood flow and pressure across at least one stenosis region of the coronary arteries are simulated using the model of coronary circulation and the patient-specific hyperemic boundary conditions. Fractional flow reserve (FFR) is calculated for the at least one stenosis region based on the simulated hyperemic blood flow and pressure.
摘要翻译： 公开了冠状动脉狭窄非侵入性评估的方法和系统。 从休息状态下获得的患者的医学图像数据中提取冠状动脉的患者特异性解剖学测量。 基于患者特异性解剖学测量和静息患者的非侵入性临床测量，计算代表冠状动脉的冠状动脉循环模型的患者特异性休息状态边界条件。 基于患者特异性解剖学测量和静息患者的非侵入性临床测量，计算代表冠状动脉的冠状动脉循环模型的患者特异性休息状态边界条件。 使用冠状动脉循环模型和患者特异性充血边界条件模拟冠状动脉至少一个狭窄区域的血流量和压力。 基于模拟的充血血流量和压力计算至少一个狭窄区域的分数流量储备（FFR）。
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公开(公告)号：US20130155064A1
公开(公告)日：2013-06-20
申请号：US13713603
申请日：2012-12-13
CPC分类号： A61B5/055 , G06T7/11 , G06T7/149 , G06T7/162 , G06T17/00 , G06T2207/20081 , G06T2207/20156 , G06T2207/30048 , G06T2207/30101
摘要： A method and system for automatic aortic valve calcification evaluation is disclosed. A patient-specific aortic valve model in a 3D medical image volume, such as a 3D computed tomography (CT) volume. Calcifications in a region of the 3D medical image volume defined based on the aortic valve model. A 2D calcification plot is generated that shows locations of the segmented calcifications relative to aortic valve leaflets of the patient-specific aortic valve model. The 2D calcification plot can be used for assessing the suitability of a patient for a Transcatheter Aortic Valve Replacement (TAVI) procedure, as well as risk assessment, positioning of an aortic valve implant, and selection of a type of aortic valve implant.
摘要翻译： 公开了一种自动主动脉瓣钙化评价方法和系统。 3D医学图像体积中的患者特异性主动脉瓣模型，例如3D计算机断层摄影（CT）体积。 基于主动脉瓣模型定义的3D医学图像体积的区域中的钙化。 生成2D钙化曲线，其显示相对于患者特异性主动脉瓣模型的主动脉瓣叶的分段钙化的位置。 2D钙化图可用于评估患者对于经导管主动脉瓣置换（TAVI）程序的适用性，以及风险评估，主动脉瓣植入物的定位和主动脉瓣植入物的选择。
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公开(公告)号：US20120323545A1
公开(公告)日：2012-12-20
申请号：US13523925
申请日：2012-06-15
IPC分类号： G06G7/48
CPC分类号： A61B6/5223 , A61B6/504 , A61B34/10 , A61B2034/108 , A61F2/24
摘要： A device for planning a transcatheter aortic valve implantation is disclosed. The device includes a segmentation module for segmenting the aorta ascendens with the aorta annulus, the aortic valves and the coronary ostia as well as the left ventricle; a determination module, which determines on the basis of the segmented data the aorta annulus plane and from this one or more angiography projections for setting an angiography device, with which the aorta annulus and the coronary ostia are able to be detected in the optimum manner for positioning the transcatheter heart valve; and an output module that outputs this information. The proposed device supports the user in the planning of a transcatheter aortic valve implantation.
摘要翻译： 公开了一种用于规划经导管主动脉瓣植入的装置。 该装置包括用于将主动脉上端与主动脉环，主动脉瓣和冠状动脉口以及左心室分割的分割模块; 确定模块，其基于所述分段数据确定所述主动脉环空平面，并且根据所述一个或多个血管造影投影来确定用于设置血管造影装置的分割数据，所述主动脉环和所述冠状动脉口能够以最佳方式被检测到 定位经导管心脏瓣膜; 以及输出该信息的输出模块。 所提出的装置支持用户规划经导管主动脉瓣植入。
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9.发明申请METHOD AND DATA-PROCESSING SYSTEM FOR DETERMINING THE PROPORTION OF CALCIUM IN CORONARY ARTERIES 有权用于确定冠状动脉钙的比例的方法和数据处理系统公开(公告)号：US20100260400A1
公开(公告)日：2010-10-14
申请号：US12729267
申请日：2010-03-23
申请人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
发明人： Dominik Bernhardt , Jörg Hausleiter , Carsten Thierfelder , Johann Uebler , Fernando Vega-Higuera
IPC分类号： G06T7/00
CPC分类号： A61B6/481 , A61B5/02007 , A61B6/032 , A61B6/504 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/70 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101
摘要： A method and a data-processing system are disclosed for determining the proportion of calcium in coronary arteries using image data from CT angiography. In at least one embodiment of the method, anatomical landmarks are detected in the image data in the region of the heart and coronary arteries are segmented taking into account the detected landmarks. Regions with an increased HU value compared to a contrast agent surroundings are segmented in the segmented coronary arteries. A proportion of calcium respectively is calculated from the segmented regions for one or more of the segmented coronary arteries. At least the last two steps are carried out fully automatically by a data-processing system. Weighting factors for the individual regions are used when calculating the proportion of calcium, which weighting factors depend on both the threshold for segmenting the respective region and the volume of said region. The method and the data-processing system of at least one embodiment allow the dose exposure of the patient to be reduced and reduce the time expenditure of the user for determining the proportion of calcium.
摘要翻译： 公开了一种使用来自CT血管造影术的图像数据来确定冠状动脉中钙的比例的方法和数据处理系统。 在该方法的至少一个实施例中，在心脏区域中的图像数据中检测解剖标志，并且考虑到检测到的界标来分割冠状动脉。 在分割冠状动脉中分割具有与造影剂周围环境相比增加的HU值的区域。 对于一个或多个分割冠状动脉的分割区域分别计算一部分钙。 至少最后两个步骤由数据处理系统完全自动执行。 当计算钙的比例时，使用各个区域的权重因子，该加权因子取决于分割各个区域的阈值和所述区域的体积。 至少一个实施方案的方法和数据处理系统允许减少患者的剂量暴露并减少用户确定钙的比例的时间支出。
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10.发明申请DEPTH DETAIL LEVEL ADJUSTMENT OF MULTI-DIMENSIONAL IMAGE DATA WITH A CLIENT/SERVER-BASED IMAGE RENDERING SYSTEM 审中-公开基于客户/服务器的图像渲染系统的深度细节水平调整多维图像数据公开(公告)号：US20080069458A1
公开(公告)日：2008-03-20
申请号：US11857491
申请日：2007-09-19
申请人： Fernando Vega-Higuera , Klaus Engel
发明人： Fernando Vega-Higuera , Klaus Engel
IPC分类号： G06K9/36
CPC分类号： G06T15/08 , G06T2200/16
摘要： In a client/server-based image archiving, image retrieval and image rendering system and method for storage, retrieval and graphical visualization of multi-dimensional digital image data such as assessment of medical image data, the detail depth level of volume data received via a data transfer network, to be shown in graphical form, is adjustable by the compressed volume data of subjects to be presented being stored with a highest-possible resolution (predetermined by an imaging system) in a databank administered by a server and directly accessibly only by this server. Although the client/server-based image archiving, image retrieval and image rendering system is able to offer volume data with this highest possible resolution to any point of the system at the request of a screen client, volume data are transferred to a screen client in a compressed form only up to a specific, spatially-variable, region-specific, or subject-specific detail depth level and are presented at the requesting screen client in graphical form. Complicated image rendering and image post-processing algorithms are implemented by the server.
摘要翻译： 在基于客户端/服务器的图像存档，图像检索和图像渲染系统以及用于存储，检索和图形化可视化多维数字图像数据的方法中，例如医学图像数据的评估，经由 以图形形式显示的数据传输网络可以通过由服务器管理的数据库中以最高可能的分辨率（由成像系统预定）存储的要被呈现的被摄体的压缩音量数据进行调节，并且仅通过 这个服务器。 虽然基于客户端/服务器的图像归档，图像检索和图像渲染系统能够根据屏幕客户端的要求向系统的任何点提供具有最高可能分辨率的卷数据，但是卷数据被传送到屏幕客户端 压缩形式只能达到特定的，空间上可变的，区域特定的或特定于细节的细节深度级别，并以图形形式呈现在请求屏幕客户端。 复杂的图像渲染和图像后处理算法由服务器实现。
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