公开(公告)号：US20230211000A1

公开(公告)日：2023-07-06

申请号：US17888072

申请日：2022-08-15

申请人： Blaze Bioscience, Inc.

发明人： Stacey J. Hansen ,  Claudia Jochheim ,  Dennis M. Miller ,  Natalie Winblade Nairn ,  Julia E. Novak ,  Mark R. Stroud ,  Valorie R. Wiss ,  Kelly Byrnes-Blake ,  Scott Presnell

IPC分类号： A61K47/64 ,  A61K47/65 ,  A61P19/02 ,  A61P13/12 ,  A61B5/00 ,  A61B6/03 ,  A61B6/00 ,  A61K49/00 ,  A61K51/08 ,  C07K14/435 ,  C07K14/47 ,  C07K16/24

CPC分类号： A61K47/6415 ,  A61K47/65 ,  A61P19/02 ,  A61P13/12 ,  A61B5/0071 ,  A61B6/037 ,  A61B6/4057 ,  A61B6/481 ,  A61K49/0056 ,  A61K49/0058 ,  A61K51/08 ,  C07K14/43518 ,  C07K14/43522 ,  C07K14/4726 ,  C07K16/244 ,  C07K16/248 ,  A61B5/055

摘要： Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.

公开(公告)号：US12048750B2

公开(公告)日：2024-07-30

申请号：US17888072

申请日：2022-08-15

申请人： Blaze Bioscience, Inc.

发明人： Stacey J. Hansen ,  Claudia Jochheim ,  Dennis M. Miller ,  Natalie Winblade Nairn ,  Julia E. Novak ,  Mark R. Stroud ,  Valorie R. Wiss ,  Kelly Byrnes-Blake ,  Scott Presnell

IPC分类号： A61K38/00 ,  A61B5/00 ,  A61B6/00 ,  A61B6/03 ,  A61B6/40 ,  A61K47/64 ,  A61K47/65 ,  A61K49/00 ,  A61K51/08 ,  A61P13/12 ,  A61P19/02 ,  C07K14/435 ,  C07K14/47 ,  C07K16/24 ,  A61B5/055 ,  A61B8/08

CPC分类号： A61K47/6415 ,  A61B5/0071 ,  A61B6/037 ,  A61B6/4057 ,  A61B6/481 ,  A61K47/65 ,  A61K49/0056 ,  A61K49/0058 ,  A61K51/08 ,  A61P13/12 ,  A61P19/02 ,  C07K14/43518 ,  C07K14/43522 ,  C07K14/4726 ,  C07K16/244 ,  C07K16/248 ,  A61B5/055 ,  A61B8/481 ,  A61B2505/05 ,  C07K2319/30 ,  C07K2319/33 ,  C07K2319/50

摘要： Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.

公开(公告)号：US11559580B1

公开(公告)日：2023-01-24

申请号：US17409661

申请日：2021-08-23

申请人： Blaze Bioscience, Inc.

发明人： Stacey J. Hansen ,  Claudia Jochheim ,  Dennis M. Miller ,  Natalie Winblade Nairn ,  Julia E. Novak ,  Mark R. Stroud ,  Valorie R. Wiss ,  Kelly Byrnes-Blake ,  Scott Presnell

IPC分类号： A61K38/00 ,  A61K47/64 ,  A61K47/65 ,  A61P19/02 ,  A61P13/12 ,  A61B5/00 ,  A61B6/03 ,  A61B6/00 ,  A61K49/00 ,  A61K51/08 ,  C07K14/435 ,  C07K14/47 ,  C07K16/24 ,  A61B5/055 ,  A61B8/08

摘要： Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.