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公开(公告)号：US20180021252A1
公开(公告)日：2018-01-25
申请号：US15655320
申请日：2017-07-20
CPC分类号： A61K9/0019 , A61B5/055 , A61B5/6842 , A61B5/687 , A61B5/6871 , A61B5/6873 , A61B17/3478 , A61B2017/00269 , A61B2017/00898 , A61B2017/00942 , A61B2090/3908 , A61B2090/3933 , A61B2090/3937 , A61K47/02 , A61K47/36
摘要： The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.
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公开(公告)号：US20180333168A1
公开(公告)日：2018-11-22
申请号：US15983968
申请日：2018-05-18
发明人： Shawn Ryan , Samuel Raybin , Matthew B. Hollyer
CPC分类号： A61B17/320016 , A61B17/00234 , A61B18/14 , A61B2017/00269 , A61B2017/0034 , A61B2017/00818 , A61B2018/00494 , A61B2018/00595 , A61B2018/00601 , A61L31/042 , A61L31/148
摘要： The present disclosure relates to the field of medical devices generally and specifically, to endoscopic systems and methods for resection of malignant and pre-malignant lesions within the gastrointestinal (GI) tract. In particular, the present disclosure relates to systems and methods for delivering injectable compositions between tissue layers (e.g., between the muscularis and submucosa layers) to elevate and stabilize the lesion for fast and efficient resection.
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公开(公告)号：US20160249889A1
公开(公告)日：2016-09-01
申请号：US15014827
申请日：2016-02-03
CPC分类号： A61B10/0266 , A61B10/0283 , A61B10/04 , A61B2010/045 , B23K26/38
摘要： A needle for collecting a tissue samples includes a needle body extending along a longitudinal axis from a proximal end to a distal end including a sharp tip for penetrating a target tissue. The needle body includes a channel extending therethrough for collecting a tissue sample therein when the distal end is inserted into the target tissue. A distal portion of the needle body has a first stiffness and a proximal portion of the body has a second stiffness of the proximal portion less than the first stiffness. The needle also includes a sleeve extending along a length of the needle body to cover the pattern along the proximal portion.
摘要翻译： 用于收集组织样本的针包括沿着纵向轴线从近端延伸到远端的针体，其包括用于穿透靶组织的尖端。 针体包括穿过其中的通道，用于当远端插入目标组织中时收集组织样本。 针体的远端部分具有第一刚度，并且主体的近侧部分具有小于第一刚度的近端部分的第二刚度。 针还包括沿着针体的长度延伸的套筒，以沿着近端部分覆盖图案。
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公开(公告)号：US20210068860A1
公开(公告)日：2021-03-11
申请号：US16952849
申请日：2020-11-19
发明人： Shawn Ryan , Samuel Raybin , Matthew B. Hollyer
摘要： The present disclosure relates to the field of medical devices generally and specifically, to endoscopic systems and methods for resection of malignant and pre-malignant lesions within the gastrointestinal (GI) tract. In particular, the present disclosure relates to systems and methods for delivering injectable compositions between tissue layers (e.g., between the muscularis and submucosa layers) to elevate and stabilize the lesion for fast and efficient resection.
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公开(公告)号：US20190262152A1
公开(公告)日：2019-08-29
申请号：US16407924
申请日：2019-05-09
摘要： A medical stent may include a tubular support structure including a plurality of struts defining a plurality of cells disposed between the plurality of struts. A polymeric coating may be disposed over the tubular support structure such that a first portion of the plurality of cells are closed by the polymeric coating in a first region of the tubular support structure and a second portion of the plurality of cells in a second region of the tubular support structure remain open to fluid flow and/or tissue ingrowth therethrough. The struts in the first region of the tubular support structure and the struts in the second region of the tubular support structure may be at least partially covered by the polymeric coating.
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公开(公告)号：US20190247301A1
公开(公告)日：2019-08-15
申请号：US16269644
申请日：2019-02-07
发明人： Matthew B. Hollyer , Samuel Raybin
CPC分类号： A61K9/0024 , A61K9/06 , A61K47/36 , A61L31/042 , A61L31/14 , A61M5/158
摘要： Compositions, e.g., gels, useful for tissue resection procedures, medical devices comprising the compositions, and related methods of preparing the compositions are discussed. The composition may comprise gellan gum, two or more salts, and water. In some aspects, the composition may be prepared by combining gellan gum and water to form a pre-mixture, heating the pre-mixture, adding two or more salts to the heated pre-mixture to form a mixture, introducing the mixture into a reservoir, and allowing the mixture to form a gel inside the reservoir. The gel may have a continuous, three-dimensional structure, and have desired gel strength and viscosity. The composition may be biocompatible and injectable from the reservoir through a needle to the target site of a patient.
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公开(公告)号：US20190261999A1
公开(公告)日：2019-08-29
申请号：US16284168
申请日：2019-02-25
发明人： John MURPHY , Daniel Sexton , Deirdre Barrett , Jillian Lee , Kevin Carbery , Samuel Raybin , Matthew B. Hollyer , Conor O'Sullivan
摘要： A medical device may include a helical coil having a plurality of turns. The plurality of turns may define a lumen. The device may also include a composition. The composition may include gellan gum, at least one salt, water, and a treatment agent. The treatment agent may be disposed in the lumen.
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公开(公告)号：US10314726B2
公开(公告)日：2019-06-11
申请号：US15260582
申请日：2016-09-09
摘要： A medical stent may include a tubular support structure including a plurality of struts defining a plurality of cells disposed between the plurality of struts. A polymeric coating may be disposed over the tubular support structure such that a first portion of the plurality of cells are closed by the polymeric coating in a first region of the tubular support structure and a second portion of the plurality of cells in a second region of the tubular support structure remain open to fluid flow and/or tissue ingrowth therethrough. The struts in the first region of the tubular support structure and the struts in the second region of the tubular support structure may be at least partially covered by the polymeric coating.
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公开(公告)号：US20140121642A1
公开(公告)日：2014-05-01
申请号：US14054374
申请日：2013-10-15
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M25/09025 , A61M2025/09141 , A61M2025/0915
摘要： Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a dual function medical device. The dual function medical device may include an inner guidewire. An outer guidewire may be disposed about the inner guidewire. The outer guidewire may include a tubular member having a plurality of slots formed therein. A torque member may be coupled to the dual function medical device. The torque member may be configured to independently attach to the inner guidewire and the outer guidewire.
摘要翻译： 公开了用于制造和使用医疗装置的医疗装置和方法。 示例性医疗设备可以包括双功能医疗设备。 双功能医疗装置可以包括内导丝。 外导丝可以围绕内导丝设置。 外导丝可以包括其中形成有多个槽的管状构件。 扭矩构件可以联接到双功能医疗装置。 扭矩构件可以被构造成独立地附接到内导丝和外导丝。
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公开(公告)号：US20220088296A1
公开(公告)日：2022-03-24
申请号：US17539445
申请日：2021-12-01
发明人： Samuel Raybin , Matthew B. Hollyer
摘要： A medical device comprising a syringe barrel, a plunger, and an injectable gel containing a coloring agent loaded in the syringe barrel. The injectable gel is sterilized by a sterilization process, such as an autoclaving process, while inside the syringe barrel. The injectable gel is adapted for injection between an upper mucosal layer and a lower layer at a target treatment site such that the upper mucosal layer separates from the lower layer and the upper mucosal layer is elevated. Also described herein are methods of forming the injectable gel.
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