摘要:
The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.
摘要:
The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.
摘要:
The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.
摘要:
A computer-implemented method as follows. Providing a list of target sequences associated with one or more organisms. Providing a list of candidate prototype sequences suspected of hybridizing to one or more of the target sequences. Generating a collection of probes corresponding to each candidate prototype sequence, each collection of probes having a set of probes for every subsequence. The sets consist of the corresponding subsequence and every variation of the corresponding subsequence formed by varying a center nucleotide of the corresponding subsequence. Generating a set of fragments corresponding to each target sequence. Calculating the binding free energy of each fragment with a perfect complimentary sequence of the fragment. Determining which extended fragments are perfect matches to any of the probes. Assembling a base call sequence corresponding to each candidate prototype sequence.
摘要:
A computer-implemented method as follows. Providing a list of target sequences associated with one or more organisms in a list of organisms. Providing a list of candidate prototype sequences suspected of hybridizing to one or more of the target sequences. Generating a collection of probes corresponding to each candidate prototype sequence, each collection of probes having a set of probes for every subsequence having a predetermined, fixed subsequence length of the corresponding candidate prototype sequence. The sets consist of the corresponding subsequence and every variation of the corresponding subsequence formed by varying a center nucleotide of the corresponding subsequence. Generating a set of fragments corresponding to each target sequence, each set of fragments having every fragment having a predetermined, fixed fragment length of the corresponding target sequence. Calculating the binding free energy of each fragment with a perfect complimentary sequence of the fragment. If any binding free energy is above a predetermined, fixed threshold, the fragment is extended one nucleotide at a time until the binding free energy is below the threshold or the fragment is the same length as the probe, generating a set of extended fragments. Determining which extended fragments are perfect matches to any of the probes. Assembling a base call sequence corresponding to each candidate prototype sequence. The base call sequence has a base call corresponding to the center nucleotide of each probe of the corresponding prototype sequence that is a perfect match to any extended fragment, but for which the other members of the set of probes containing the perfect match probe are not perfect matches to any extended fragment and a non-base call in all other circumstances.
摘要:
The present invention relates to a manufacturing method of a printing circuit board. The manufacturing method mainly includes: forming one or more cylindrical micro-radiators by cutting a high conductive and electrical insulating substrate according to predetermined size; manufacturing one or more mounting holes in copper clad plates and prepregs; embedding the cylindrical micro-radiators into the mounting holes. The present invention combines the micro-radiator with high thermal conductivity and traditional stiffness printing circuit board. The printing circuit board with micro-radiators has the advantages of high thermal conductivity and stable heat transfer, and also has the advantages of routing flexibility and reliable electrical connections.
摘要:
An indoor testing device for multiple rotor-containing flying objects including a main support having a plurality of linking members, a plurality of mechanical arms, a plurality of trays, and control units of the mechanical arms. The main support is disposed vertically. The mechanical arms are separately disposed on the linking members of the main support with different height. The trays are separately disposed on one end of the mechanical arms for receiving rotor-containing flying objects, and the control units are disposed on the mechanical arms and rotate therewith. The device can be used for the cooperation and coordination test of multiple rotor-containing flying objects and autonomous control experiments of a single rotor-containing flying object. The tests have high stimulation and improve the usability of the experimental results in the actual system.
摘要:
An API for prefetching map data receives a prefetch request for an indicated geographic area from a software application. In response, the API retrieves map data corresponding to the indicated geographic area from a map data provider and stores the map data in a map data cache without causing a digital map based on the map data to be displayed on the display device. The map data cache is accessible to the software application only via the API. Subsequently to storing the map data in the map data cache, the API receives a request to render the digital map from the software application and, in response to the request to render the map image, renders the map image for display on a display device using the map data stored in the map data cache.
摘要:
The present invention provides an array substrate, a liquid crystal display device comprising the same, and a method for forming the same. The array substrate comprises a gate line, a data line, a signal line and a pixel electrode formed thereon. The gate line intersects the data line to define a plurality of pixel regions in which the pixel electrodes are formed. Each of the pixel electrodes overlaps the signal line to form a first sensing capacitor and overlaps the gate line to form a second sensing capacitor.
摘要:
A liquid crystal display is disclosed which comprises a first substrate and a second substrate, which are supported by primary spacers. At least a secondary spacer is provided on the first substrate, and the secondary spacer is covered by a conductive electrode. An X-direction detecting wire and a Y-direction detecting wire perpendicular to each other are provided on the second substrate, the X-direction detecting wire and the Y-direction detecting wire are respectively provided with a first connection electrode and a second connection electrode; and positions of the first and second connection electrodes on the second substrate correspond to a position of the secondary spacer on the first substrate; under a press condition, at least one of the first and second connection electrodes contacts with the secondary spacer and is connected with the conductive electrode on the secondary spacer.