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1.发明申请Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives 有权氨基烷基 - 酰胺基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-苯并二氢吡喃-6-基衍生物公开(公告)号：US20060252821A1
公开(公告)日：2006-11-09
申请号：US11400283
申请日：2006-04-10
申请人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： A61K31/353
CPC分类号： C07D311/72 , C07D405/12
摘要： Novel compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.
摘要翻译： 对应于式I的新型化合物，其中R 1，R 2，R 3，R 4，R 4， R 5，R 6，R 7，R 8，R 9，R 9， SUP> 10和n具有在说明书中给出的含义，以及制备这些化合物的方法和该方法的中间产物。 此外，包含式I化合物和相关治疗方法的药物组合物。
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2.发明授权Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives 有权氨基烷基 - 酰胺基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-苯并二氢吡喃-6-基衍生物公开(公告)号：US07714150B2
公开(公告)日：2010-05-11
申请号：US11400283
申请日：2006-04-10
申请人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： C07D311/00 , C07D413/00 , C07D405/00
CPC分类号： C07D311/72 , C07D405/12
摘要： Compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.
摘要翻译： 对应于式I的化合物，其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 10和n具有在说明书中给出的含义，以及制备这些化合物和中间产物的方法 这个过程。 此外，包含式I化合物和相关治疗方法的药物组合物。
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3.发明申请Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them 有权酰基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-色烯-6-基化合物，其制备方法和中间体以及含有它们的药物组合物公开(公告)号：US20050148659A1
公开(公告)日：2005-07-07
申请号：US10961368
申请日：2004-10-12
申请人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： C07D311/68 , C07D407/12 , A61K31/353 , C07D311/76 , C07D45/02
CPC分类号： C07D407/12 , C07D311/68
摘要： Compounds corresponding to formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description; a process for the preparation of these compounds; intermediate products used to prepare such compounds, and pharmaceutical compositions containing such compounds.
摘要翻译： 对应于式I的化合物：其中R 1，R 2，R 3，R 4，R 4， SUP> 5＆lt; 6＆gt;具有说明书中给出的含义; 一种制备这些化合物的方法; 用于制备这些化合物的中间产物，和含有这些化合物的药物组合物。
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4.发明授权Use of amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl-compounds in the treatment of cardiac arrhythmia and other disease states 有权酰胺甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-色烯-6-基化合物在治疗心律失常和其他疾病状态中的应用公开(公告)号：US07534903B2
公开(公告)日：2009-05-19
申请号：US12016798
申请日：2008-01-18
申请人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： C07D311/00 , A01N43/08
CPC分类号： C07D407/12 , C07D311/68
摘要： The use of compounds corresponding to formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description for treating cardiac arrhythmias and other disease states.
摘要翻译： 使用对应于式I的化合物：其中R1，R2，R3，R4，R5和R6具有描述中给出的用于治疗心律失常和其他疾病状态的含义。
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5.发明申请Use of Amidomethyl-Substituted 2-(4-Sulfonylamino)-3-Hydroxy-3,4-Dihydro-2H-Chromen-6-yl-Compounds in the Treatment of Cardiac Arrhythmia and Other Disease States 有权酰胺甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-色烯-6-基化合物在心律失常和其他疾病状态的治疗中的应用公开(公告)号：US20080113999A1
公开(公告)日：2008-05-15
申请号：US12016798
申请日：2008-01-18
申请人： David SYKES , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： David SYKES , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： A61K31/496 , A61K31/353
CPC分类号： C07D407/12 , C07D311/68
摘要： The use of compounds corresponding to formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description for treating cardiac arrhythmias and other disease states.
摘要翻译： 使用对应于式I的化合物：其中R 1，R 2，R 3，R 4， R 5和R 6具有治疗心律失常和其他疾病状态的描述中给出的含义。
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6.发明授权Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them 有权酰基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-色烯-6-基化合物，其制备方法和中间体以及含有它们的药物组合物公开(公告)号：US07368582B2
公开(公告)日：2008-05-06
申请号：US10961368
申请日：2004-10-12
申请人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： David Sykes , Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： C07D311/00
CPC分类号： C07D407/12 , C07D311/68
摘要： Compounds corresponding to formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description; a process for the preparation of these compounds; intermediate products used to prepare such compounds, and pharmaceutical compositions containing such compounds.
摘要翻译： 对应于式I的化合物：其中R 1，R 2，R 3，R 4，R 4， SUP> 5＆lt; 6＆gt;具有说明书中给出的含义; 一种制备这些化合物的方法; 用于制备这些化合物的中间产物，和含有这些化合物的药物组合物。
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7.发明授权Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives 有权氨基烷基 - 酰胺基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-苯并二氢吡喃-6-基衍生物公开(公告)号：US08273905B2
公开(公告)日：2012-09-25
申请号：US12394662
申请日：2009-02-27
申请人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： C07D311/00 , C07D411/00 , C07D405/00
CPC分类号： C07D311/72 , C07D405/12
摘要： Compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.
摘要翻译： 对应于式I的化合物，其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 10和n具有在说明书中给出的含义，以及制备这些化合物和中间产物的方法 这个过程。 此外，包含式I化合物和相关治疗方法的药物组合物。
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8.发明申请Aminoalkyl-Amidomethyl-Substituted 2-(4-Sulphonylamino)- 3-Hydroxy-3,4-Dihydro-2H-Chroman-6-yl Derivatives 有权氨基烷基 - 酰氨基甲基取代的2-（4-磺酰基氨基）-3-羟基-3,4-二氢-2H-色满-6-基衍生物公开(公告)号：US20090203686A1
公开(公告)日：2009-08-13
申请号：US12394662
申请日：2009-02-27
申请人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
发明人： Brian Moloney , Lester Marrison , Dieter Ziegler , Michael Mlinaric , Christiane Boecker , Reinhard Brueckner , Michael Weske , Klaus Witte , Yvan Fischer
IPC分类号： A61K31/5377 , A61K31/497 , A61K31/4025 , A61K31/35 , C07D413/14 , C07D405/10 , C07D311/00
CPC分类号： C07D311/72 , C07D405/12
摘要： Compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.
摘要翻译： 对应于式I的化合物，其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 10和n具有在说明书中给出的含义，以及制备这些化合物和中间产物的方法 这个过程。 此外，包含式I化合物和相关治疗方法的药物组合物。
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公开(公告)号：US06821992B1
公开(公告)日：2004-11-23
申请号：US10049976
申请日：2002-07-09
申请人： Tracey Cooke , David Hardy , Brian Moloney , Peter Stanley Thomas , Chris Richard Steele , Geoffrey Gower Briggs
发明人： Tracey Cooke , David Hardy , Brian Moloney , Peter Stanley Thomas , Chris Richard Steele , Geoffrey Gower Briggs
IPC分类号： A01N4340
CPC分类号： C07D231/12 , A01N43/40 , A01N47/30 , C07D213/61 , C07D233/56 , C07D249/08 , C07D401/06 , C07D401/12 , C07D409/12 , C07D417/12
摘要： The invention relates to compounds of general formula I, where A1, R1, R2 and Y are as defined in the description; and to their use as phytopathogenic fungicides.
摘要翻译： 本发明涉及通式I的化合物，其中A 1，R 1，R 2和Y如说明书中所定义; 并将其用作植物病原性杀真菌剂。
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公开(公告)号：US5045147A
公开(公告)日：1991-09-03
申请号：US275313
申请日：1988-11-23
申请人： Vernon M. Benson , Dee R. Gill , Boyd L. Hatch , John A. Johnson , Brian Moloney , Noel I. Shepherd , Keith G. Shupe , William J. Weis
发明人： Vernon M. Benson , Dee R. Gill , Boyd L. Hatch , John A. Johnson , Brian Moloney , Noel I. Shepherd , Keith G. Shupe , William J. Weis
IPC分类号： B29C70/16 , B29C53/58 , B29C53/80 , B29C69/00 , B65H54/64 , B65H54/71 , B65H57/16 , B65H81/00
CPC分类号： B29C69/002 , B29C53/58 , B29C53/8016 , Y10T156/1348 , Y10T156/1715 , Y10T156/1788 , Y10T156/1795
摘要： A filament winding system includes a head that selects the number of tows to be within a winding band while winding and positioning the winding band directly on the mandrel according to contours of the mandrel. Half of the tows are conveyed in an upper portion of the head and the remaining half are conveyed in a lower portion of the head with both halves meeting at an applicating roller at the discharge end of the tows. The head includes cut and add assemblies wherein the individual tows are selectively cut and later can be added to the band.
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