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公开(公告)号：US5906234A
公开(公告)日：1999-05-25
申请号：US734603
申请日：1996-10-22
CPC分类号： A61F2/30942 , A61F2/30771 , B22C7/02 , B22C9/04 , A61F2002/30011 , A61F2002/30929 , A61F2002/30952 , A61F2002/30957 , A61F2002/30962 , A61F2002/30971 , A61F2250/0023 , A61F2310/00029 , B29C2043/3652 , B29C43/36 , B29C67/0051 , B29L2031/7532
摘要： Methods are provided for producing investment cast articles, such as orthopedic implants or portions thereof, having at least a partially textured surface that is formed during casting of the article. In an exemplary method, a textured metal casting is produced by creating a heat destructible pattern and spraying the pattern with a texturing material to cause the texturing material to form a textured surface on at least a portion of the pattern. In another embodiment, a textured template is pressed against a heat softenable pattern to provide a textured pattern. With respect to each of these methods, a shell is the created around the textured pattern form a mold, and the pattern is removed from the shell. Molten metal is introduced into the mold and allowed to harden, after which the mold is removed. In yet another embodiment a textured pattern for investment casting is provided by creating a textured model and enveloping it with a resilient material to create a resilient mold. The textured model is removed from the resilient mold and the mold is filled with investment casting wax to create a textured pattern.
摘要翻译： 提供了用于生产投射式铸造制品的方法，例如矫形植入物或其部分，其具有在制品的铸造期间形成的至少部分纹理化的表面。 在示例性方法中，通过产生热可破坏图案并且用纹理材料喷涂图案来产生纹理金属铸件，以使纹理化材料在图案的至少一部分上形成纹理表面。 在另一个实施例中，纹理模板被压靠在可热软化图案上以提供纹理图案。 关于这些方法中的每一种，围绕纹理图案形成模具形成的壳体，并且将图案从壳体移除。 将熔融金属引入模具中并使其硬化，之后除去模具。 在另一个实施例中，通过产生纹理模型并用弹性材料包围它以产生弹性模具来提供用于熔模铸造的纹理图案。 纹理模型从弹性模具中移除，并且模具中充满熔模铸造蜡以产生纹理图案。
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公开(公告)号：US5746272A
公开(公告)日：1998-05-05
申请号：US724732
申请日：1996-09-30
CPC分类号： A61F2/30771 , B22C7/02 , B22C9/04 , A61F2/3094 , A61F2002/30957 , A61F2310/00029
摘要： Methods are provided for producing investment cast articles, such as orthopedic implants, or portions thereof, having at least a partially textured surface that is formed during casting of the article. In an exemplary method, a textured metal casting is produced by creating a heat destructible pattern and spraying the pattern with a texturing material to cause the texturing material to form a textured surface on at least a portion of the pattern. In another embodiment, a textured template is pressed against a heat softenable pattern to provide a textured pattern. With respect to each of these methods, a shell is created around the textured pattern to form a mold, and the pattern is removed from the shell. Molten metal is introduced into the mold and allowed to harden, after which the mold is removed.
摘要翻译： 提供了用于生产投射式铸造制品的方法，例如整形外科植入物或其部分，其具有在制品的铸造期间形成的至少部分纹理化的表面。 在示例性方法中，通过产生热可破坏图案并且用纹理材料喷涂图案来产生纹理金属铸件，以使纹理化材料在图案的至少一部分上形成纹理表面。 在另一个实施例中，纹理模板被压靠在可热软化图案上以提供纹理图案。 关于这些方法中的每一种，在纹理图案周围形成壳以形成模具，并且将图案从壳体移除。 将熔融金属引入模具中并使其硬化，之后除去模具。
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公开(公告)号：US5782289A
公开(公告)日：1998-07-21
申请号：US724494
申请日：1996-09-30
CPC分类号： A61F2/30771 , B22C7/02 , B22C9/04 , A61F2/3094 , A61F2002/30957 , A61F2310/00029
摘要： Methods are provided for producing investment cast articles, such as orthopedic implants, or portions thereof, having at least a partially textured surface that is formed during casting of the article. In an exemplary method, a textured metal casting is produced by creating a heat destructible pattern and spraying the pattern with a texturing material to cause the texturing material to form a textured surface on at least a portion of the pattern. In another embodiment, a textured template is pressed against a heat softenable pattern to provide a textured pattern. With respect to each of these methods, a shell is the created around the textured pattern to form a mold, and the pattern is removed from the shell. Molten metal is introduced into the mold and allowed to harden, after which the mold is removed.
摘要翻译： 提供了用于生产投射式铸造制品的方法，例如整形外科植入物或其部分，其具有在制品的铸造期间形成的至少部分纹理化的表面。 在示例性方法中，通过产生热可破坏图案并且用纹理材料喷涂图案来产生纹理金属铸件，以使纹理化材料在图案的至少一部分上形成纹理表面。 在另一个实施例中，纹理模板被压靠在可热软化图案上以提供纹理图案。 关于这些方法中的每一种，在纹理图案周围形成壳体以形成模具，并且将图案从壳体移除。 将熔融金属引入模具中并使其硬化，之后除去模具。
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公开(公告)号：US20130084310A1
公开(公告)日：2013-04-04
申请号：US13250086
申请日：2011-09-30
申请人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
发明人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
CPC分类号： A61K35/17 , A61K35/14 , A61K35/19 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1841 , A61K38/1866 , A61K38/1875 , A61K38/363 , A61K38/55 , A61L15/32 , A61L27/225 , A61L27/38 , A61L27/54 , A61L2300/414 , A61K2300/00
摘要： Compositions and methods are provided for tissue constructs that promote wound healing. The composition comprises a dimensionally stable fibrin construct for local administration to a wound site or region. In one embodiment, the fibrin construct is a wound healing composition, including components that promote wound healing, such as platelets, growth factors, white blood cells and fibrin clots. In another embodiment, the tissue treatment composition includes (i) aggregated fibrin, (ii) blood cells, and (iii) optionally, growth factors and/or other proteins.
摘要翻译： 为促进伤口愈合的组织结构提供组合物和方法。 组合物包含用于局部施用于伤口部位或区域的尺寸稳定的纤维蛋白构建体。 在一个实施方案中，纤维蛋白构建体是伤口愈合组合物，包括促进伤口愈合的成分，例如血小板，生长因子，白细胞和纤维蛋白凝块。 在另一个实施方案中，组织处理组合物包括（i）聚集的纤维蛋白，（ii）血细胞，和（iii）任选的生长因子和/或其它蛋白质。
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公开(公告)号：US08491595B2
公开(公告)日：2013-07-23
申请号：US11862509
申请日：2007-09-27
申请人： Piero Volpi , Douglas A. Fifolt , Jose E. Lizardi
发明人： Piero Volpi , Douglas A. Fifolt , Jose E. Lizardi
CPC分类号： A61B17/88 , A61B17/1714 , A61B17/1764
摘要： Devices and methods are provided for positioning and forming bone tunnels. In one embodiment, a surgical drill guide apparatus is provided. The apparatus can include a first guide member having a longitudinal passageway extending therethrough for aiming a first guide pin along a first path to form a first bone tunnel. The apparatus can also include a second guide member having a longitudinal passageway extending therethrough for aiming a second guide pin along a second path to form a second bone tunnel. The first and second guide members can extend at an angle relative to one another and they can be offset such that axes of the guide members do not intersect.
摘要翻译： 提供了用于定位和形成骨隧道的装置和方法。 在一个实施例中，提供了一种外科钻子引导装置。 该装置可以包括第一引导构件，其具有延伸穿过其中的纵向通道，用于沿着第一路径瞄准第一引导销以形成第一骨隧道。 该装置还可以包括具有延伸穿过其中的纵向通道的第二引导构件，用于沿着第二路径瞄准第二引导销以形成第二骨隧道。 第一和第二引导构件可以相对于彼此成一定角度延伸，并且它们可以偏移，使得引导构件的轴线不相交。
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公开(公告)号：US20130325124A1
公开(公告)日：2013-12-05
申请号：US13487880
申请日：2012-06-04
申请人： Douglas A. Fifolt
发明人： Douglas A. Fifolt
CPC分类号： A61B17/8897 , A61B17/1675 , A61B17/1714 , A61B17/1764 , A61B2017/564
摘要： Methods and devices are provided for placing surgical guide pins, reamers, and ligament grafts into bone. In one exemplary embodiment, the method can include advancing a guide pin that includes a proximal rigid portion and a flexible distal portion. The rigid proximal portion can be advanced into a femoral tunnel such that the flexible distal portion extends across an intra-articular space. The flexible portion of the guide pin can be bent to adjust a distance between the guide pin and articular cartilage. A cannulated reamer can be advanced over the flexible portion of the guide pin and the reamer can be manipulated to avoid contact with the articular cartilage in the intra-articular space. A ligament graft can be secured in the femoral tunnel created by the guide pin and the reamer.
摘要翻译： 提供的方法和装置用于将外科手术引导针，铰刀和韧带移植物放入骨中。 在一个示例性实施例中，该方法可以包括推进包括近端刚性部分和柔性远侧部分的引导销。 刚性近端部分可以推进到股骨隧道中，使得柔性远侧部分延伸穿过关节内空间。 引导销的柔性部分可以弯曲以调节引导销和关节软骨之间的距离。 插管铰刀可以在引导销的柔性部分上推进，并且可以操纵铰刀以避免与关节内空间中的关节软骨接触。 韧带移植物可以固定在由引导销和铰刀产生的股骨隧道中。
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公开(公告)号：US20080103506A1
公开(公告)日：2008-05-01
申请号：US11862509
申请日：2007-09-27
申请人： Piero Volpi , Douglas A. Fifolt , Jose E. Lizardi
发明人： Piero Volpi , Douglas A. Fifolt , Jose E. Lizardi
IPC分类号： A61B17/58
CPC分类号： A61B17/88 , A61B17/1714 , A61B17/1764
摘要： Devices and methods are provided for positioning and forming bone tunnels. In one embodiment, a surgical drill guide apparatus is provided. The apparatus can include a first guide member having a longitudinal passageway extending therethrough for aiming a first guide pin along a first path to form a first bone tunnel. The apparatus can also include a second guide member having a longitudinal passageway extending therethrough for aiming a second guide pin along a second path to form a second bone tunnel. The first and second guide members can extend at an angle relative to one another and they can be offset such that axes of the guide members do not intersect.
摘要翻译： 提供了用于定位和形成骨隧道的装置和方法。 在一个实施例中，提供了一种外科钻子引导装置。 该装置可以包括第一引导构件，其具有延伸穿过其中的纵向通道，用于沿着第一路径瞄准第一引导销以形成第一骨隧道。 该装置还可以包括具有延伸穿过其中的纵向通道的第二引导构件，用于沿着第二路径瞄准第二引导销以形成第二骨隧道。 第一和第二引导构件可以相对于彼此成一定角度延伸，并且它们可以偏移，使得引导构件的轴线不相交。
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公开(公告)号：US10022174B2
公开(公告)日：2018-07-17
申请号：US13487880
申请日：2012-06-04
申请人： Douglas A. Fifolt
发明人： Douglas A. Fifolt
摘要： Methods and devices are provided for placing surgical guide pins, reamers, and ligament grafts into bone. In one exemplary embodiment, the method can include advancing a guide pin that includes a proximal rigid portion and a flexible distal portion. The rigid proximal portion can be advanced into a femoral tunnel such that the flexible distal portion extends across an intra-articular space. The flexible portion of the guide pin can be bent to adjust a distance between the guide pin and articular cartilage. A cannulated reamer can be advanced over the flexible portion of the guide pin and the reamer can be manipulated to avoid contact with the articular cartilage in the intra-articular space. A ligament graft can be secured in the femoral tunnel created by the guide pin and the reamer.
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公开(公告)号：US10849931B2
公开(公告)日：2020-12-01
申请号：US13250086
申请日：2011-09-30
申请人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
发明人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
IPC分类号： A61K35/14 , A61K35/17 , A61K38/18 , A61L27/22 , A61L27/38 , A61K35/19 , A61L27/54 , A61L15/32 , A61K38/36 , A61K38/55
摘要： Compositions and methods are provided for tissue constructs that promote wound healing. The composition comprises a dimensionally stable fibrin construct for local administration to a wound site or region. In one embodiment, the fibrin construct is a wound healing composition, including components that promote wound healing, such as platelets, growth factors, white blood cells and fibrin clots. In another embodiment, the tissue treatment composition includes (i) aggregated fibrin, (ii) blood cells, and (iii) optionally, growth factors and/or other proteins.
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公开(公告)号：US07889069B2
公开(公告)日：2011-02-15
申请号：US11097499
申请日：2005-04-01
申请人： Douglas A. Fifolt , Miki Rosenberg
发明人： Douglas A. Fifolt , Miki Rosenberg
IPC分类号： G08B1/08
CPC分类号： A61B5/0002 , A61B5/0031 , A61B5/7232
摘要： A device and method for monitoring a patient having a sensing device taking sensor data continuously and a transmitter located on the patient and internally powered. The transmitter is normally in a power-down state and powered-up for transmitting the sensor data. A receiver is located remote from the patient and receives the sensor data transmitted wirelessly from the transmitter. The transmission is typically a burst and can also be initiated on a command. For the burst, the sensor data is accumulated over a first period. The transmitter can transmit the sensor data over a second period of time. The second period of time is shorter than the first period of time. Once the transmission is complete, transmitter can be powered down. A further step displays the sensor data at the receiver in pseudo real-time. The display is shifted by a sum of the first and the second period of time.
摘要翻译： 一种用于监测患者的装置和方法，所述患者具有连续获取传感器数据的感测装置和位于患者身上且内部供电的发射器。 发射机通常处于掉电状态，并通电以传输传感器数据。 接收器位于远离病人的位置，并接收从发射机无线传输的传感器数据。 传输通常是突发，也可以在命令上启动。 对于突发，传感器数据在第一周期内累积。 发射机可以在第二个时间段内传输传感器数据。 第二个时间段比第一个时间段短。 一旦传输完成，发射机可以掉电。 进一步的步骤在伪实时地显示接收机处的传感器数据。 显示器移动了第一和第二时间段的总和。
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