摘要:
Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
摘要:
Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD71 in comparison to healthy cells. Also provided are antagonists or agonists of CD71, and methods for screening agents that modulate the CD71 level or activity in vivo or in vitro.
摘要:
Methods and compositions for diagnosing, detecting a pancreatic disease associated with differential expression of PCATs (e.g., CD49b, CD51, CD71 and E-Cadherin) in comparison to healthy cells.
摘要:
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
摘要:
Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
摘要:
Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD51 in comparison to healthy cells. Also provided are antagonists or agonists of CD51, and methods for screening agents that modulate the CD51 level or activity in vivo or in vitro.
摘要:
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
摘要:
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
摘要:
An elongated shaft has a shock-absorbing core, a fiber-reinforced durable plastic outer skin encasing the core, and an elongated stiffening member encased within the core. The elongated stiffening member may be a spar or a hollow tube. If it is a hollow tube, the tube may contain a weight that moves along the inside of the tube as the shaft is swung. The shaft also has a way to attach athletic equipment, such as a lacrosse head frame and net, to one end.
摘要:
A tool having: (a) an inner-surface defining a hollow extending within the tool and sized to accept the stem at an end-port of the hollow and to permit a sliding of the hollow along the stem; (b) an integral handle having a grip surface around at least a portion of the hollow; and (c) at one end of the tool and located a distance, dN, from the handle, is an integral barbed-end comprising a plurality of barbs, each barb having a length of sharp edge. The length of sharp edge of a barb is disposed between a tapered surface and a blade surface oriented generally orthogonal to the inner-surface of the hollow such that the blade surface will contact the flexible packing for removal. The tool can also have an integral second barbed-end. Each of the barbs of a barbed-end can be curve-tooth shaped; or a barbed-end can have a plurality of barbs arranged such that each of the tapered surfaces is concentrically oriented along an axis of the inner-surface. Also, a method having the steps: (a) inserting the stem into an end-port of a hollow extending within the tool and sliding an inner-surface defining the hollow, along the stem; (b) upon penetrating the flexible packing with at least a portion of a length of sharp edge of a first barb of a barbed-end of the tool, applying a tangential-twisting force to an integral handle having a grip surface, slidably-revolving the hollow around the stem, to further penetrate the flexible packing such that a blade surface of the first barb contacts the flexible packing; and (c) applying an axial force to the handle in a direction opposite to an initial force used during the step of inserting, and pulling the flexible packing in contact with the first barb in the opposite direction along the stem.