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公开(公告)号：US09883813B2
公开(公告)日：2018-02-06
申请号：US15240725
申请日：2016-08-18
发明人： Qingguo Zeng , Rémi DuBois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
IPC分类号： A61B5/044 , A61B5/04 , A61B5/00 , A61B5/0452 , A61N1/36 , A61B5/046 , A61B5/0464 , A61B18/14 , A61B5/0408 , A61B5/042
CPC分类号： A61B5/04012 , A61B5/0044 , A61B5/04085 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/486 , A61B5/7264 , A61B18/1492 , A61B2576/023 , A61N1/36
摘要： A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
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公开(公告)号：US10729345B2
公开(公告)日：2020-08-04
申请号：US15971559
申请日：2018-05-04
发明人： Qing Lou , Jeffrey B. Adair , Qingguo Zeng , Ping Jia , Ryan Bokan , Connor Edel , Rahsean Ellis , Brian P. George , Raja Ghanem , Timothy G. Laske
摘要： For example, one or more non-transitory computer-readable media includes executable instructions to perform a method. The method includes defining a plurality of spatial regions distributed across a geometric surface. At least one wave front that propagates across the geometric surface is detected based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval. An indication of conduction velocity of the wave front is determined for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region. Slow conduction activity is identified for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold. Conduction data is stored in memory to represent each slow conduction event.
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公开(公告)号：US10575749B2
公开(公告)日：2020-03-03
申请号：US15498662
申请日：2017-04-27
发明人： Qing Lou , Meredith E. Stone , Qingguo Zeng , Jeffrey B. Adair , Connor S. Edel , Ping Jia , Kevin R. Ponziani , Brian P. George , Ryan M. Bokan , Matthew J. Sabo , Vladimir A. Turovskiy , Ketal C. Patel , Charulatha Ramanathan
IPC分类号： A61B5/0468 , A61B5/0432 , A61B5/044 , A61B5/0472 , A61B5/00
摘要： An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.
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公开(公告)号：US09668664B2
公开(公告)日：2017-06-06
申请号：US14156903
申请日：2014-01-16
发明人： Qingguo Zeng , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
CPC分类号： A61B5/04012 , A61B5/0044 , A61B5/04085 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/486 , A61B5/7264 , A61B18/1492 , A61B2576/023 , A61N1/36
摘要： A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
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公开(公告)号：US09427166B2
公开(公告)日：2016-08-30
申请号：US14032552
申请日：2013-09-20
发明人： Remi Dubois , Brian P. George , Charulatha Ramanathan , Qingguo Zeng , Maria Strom , Venkatesh Vasudevan , Ryan Bokan , Ping Jia
IPC分类号： A61B5/044 , A61B5/04 , A61B5/00 , A61B18/14 , A61B5/046 , A61B5/0464 , A61B5/0408 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B5/04012 , A61B5/04085 , A61B5/044 , A61B5/046 , A61B5/0464 , A61B5/4836 , A61B5/6823 , A61B5/7242 , A61B5/7257 , A61B2017/00044 , A61B2017/00053 , A61B2018/00839 , A61B2018/00869
摘要： A non-transitory computer-readable medium can have instructions executable by a processor. The instructions can include an electrogram reconstruction method to generate reconstructed electrogram signals for each of a multitude of points residing on or near a predetermined cardiac envelope based on geometry data and non-invasively measured body surface electrical signals. The instructions can include a phase calculator to compute phase signals for the multitude of points based on the reconstructed electrogram signals and a visualization engine to generate an output based on the computed phase signals.
摘要翻译： 非暂时性计算机可读介质可以具有可由处理器执行的指令。 该指令可以包括电描绘图重建方法，用于基于几何数据和非侵入性测量的身体表面电信号，为驻留在预定心脏包络上或附近的多个点的每一个生成重建的电描记图信号。 指令可以包括相位计算器，用于基于重建的电描记信号来计算多个点的相位信号，以及可视化引擎，以基于所计算的相位信号生成输出。
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公开(公告)号：US11826148B2
公开(公告)日：2023-11-28
申请号：US17543116
申请日：2021-12-06
发明人： Ping Jia , Charulatha Ramanathan , Maria Strom , Brian P. George , Lalita Bhetwal , Harold Wodlinger , Jonathan D. Small
IPC分类号： A61B5/316 , A61B5/00 , A61B5/333 , A61B5/339 , A61B5/349 , A61N1/365 , A61B5/283 , A61B18/12 , A61B18/00
CPC分类号： A61B5/316 , A61B5/0036 , A61B5/283 , A61B5/333 , A61B5/339 , A61B5/349 , A61B5/748 , A61B18/12 , A61N1/365 , A61B2018/00839
摘要： Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.
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公开(公告)号：US11224374B2
公开(公告)日：2022-01-18
申请号：US15384620
申请日：2016-12-20
发明人： Ping Jia , Charulatha Ramanathan , Maria Strom , Brian P. George , Lalita Bhetwal , Harold Wodlinger , Jonathan D. Small
IPC分类号： A61B5/316 , A61B5/00 , A61B5/283 , A61B5/333 , A61B5/339 , A61B5/349 , A61N1/365 , A61B18/00 , A61B18/12
摘要： Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.
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公开(公告)号：US10376173B2
公开(公告)日：2019-08-13
申请号：US15498719
申请日：2017-04-27
发明人： Brian P. George , Meredith E. Stone , Qingguo Zeng , Qing Lou , Connor S. Edel , Ping Jia , Jeffrey B. Adair , Vladimir A. Turovskiy , Matthew J. Sabo , Ryan M. Bokan , Ketal C. Patel , Charulatha Ramanathan , John E. Anderson , Andrew E. Hoover , Cheng Yao
IPC分类号： A61B5/00 , A61B5/0456 , A61B5/04 , A61B5/0408 , A61B5/0452
摘要： An example method includes performing amplitude-based detection to determine location of R-peaks for a plurality of electrograms. The method also includes performing wavelet-based detection to determine location of R-peaks for the plurality of electrograms. The method also includes adjusting the location of the R-peaks determined by the wavelet-based detection of R-peaks based on the location of R-peaks determined by the amplitude-based detection of R-peaks. The method also includes storing, in memory, R-peak location data to specify R-peak locations for the plurality of electrograms based on the adjusting.
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公开(公告)号：US09737267B2
公开(公告)日：2017-08-22
申请号：US14156951
申请日：2014-01-16
发明人： Maria Strom , Qingguo Zeng , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Brian P. George
IPC分类号： A61B5/00 , A61B5/0402 , A61B5/044 , A61B5/0476
CPC分类号： A61B5/7282 , A61B5/0042 , A61B5/0044 , A61B5/0402 , A61B5/044 , A61B5/0476 , A61B5/7425
摘要： A method can include storing a plurality of data sets including values computed for each of a plurality of points for a given spatial region of tissue, the values in each of the data sets characterizing electrical information for each respective point of the plurality of points for a different time interval. The method can also include combining the values computed for each of a plurality of points in a first interval, corresponding to a first map, with the values for computed for each of the respective plurality of points in another interval and to normalize the combined values relative to a common scale. The method can also include generating a composite map for the given spatial region based on the combined values that are normalized.
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公开(公告)号：US20140200473A1
公开(公告)日：2014-07-17
申请号：US14156903
申请日：2014-01-16
发明人： QINGGUO ZENG , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
CPC分类号： A61B5/04012 , A61B5/0044 , A61B5/04085 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/486 , A61B5/7264 , A61B18/1492 , A61B2576/023 , A61N1/36
摘要： A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
摘要翻译： 一种方法可以确定焦点激活的一个或多个来源。 该方法可以包括基于跨越时间的电数据在几何表面上分布的多个节点处的电信号的计算阶段。 该方法可以基于分析所计算的给定候选节点的相位和幅度来确定多个节点中的给定候选节点是否是焦点。 可以生成图形图，以便可视化在几何表面上检测到的焦点。
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