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公开(公告)号：US10955535B2
公开(公告)日：2021-03-23
申请号：US15512377
申请日：2015-09-25
申请人： CENTRE NATIONAL DE LA RE-CHERCHE SCIENTIFIQUE—CNRS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
摘要： According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc·Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.
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公开(公告)号：US20170276775A1
公开(公告)日：2017-09-28
申请号：US15512377
申请日：2015-09-25
申请人： CENTRE NATIONAL DE LA RE-CHERCHE SCIENTIFIQUE-CNRS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
CPC分类号： G01S7/52046 , A61B8/4477 , A61B8/5207 , G01S15/8959 , G01S15/8977
摘要： According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc.Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.
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公开(公告)号：US20240183824A1
公开(公告)日：2024-06-06
申请号：US18269158
申请日：2021-12-21
申请人： ICONEUS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , Centre National de la Recherche Scientifique , ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
IPC分类号： G01N29/06 , G01N29/26 , G01N33/483
CPC分类号： G01N29/0654 , G01N29/26 , G01N33/4833 , G01N2291/023 , G01N2291/106
摘要： An ultrasound probe includes a connector and a probe head that includes a mount located in a tip part of the probe head, various linear matrices of transducers that emit acoustic waves with a given central wavelength and detect backscattered acoustic waves. The linear matrices are electrically connected to the connector, wherein each linear matrix from the linear matrices of transducers includes a first side along a first direction and a second side along a second direction. The second side is smaller than the first side. The linear matrices are fixed to the mount and juxtaposed on the mount with the first sides adjacent. Each linear matrix from the linear matrices of transducers is covered with a single cylindrical acoustic lens that focuses the acoustic waves emitted by the linear matrix. Each cylindrical acoustic lens includes a cylindrical axis substantially parallel to the first direction.
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公开(公告)号：US10653387B2
公开(公告)日：2020-05-19
申请号：US15323305
申请日：2015-06-29
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS , Université Pierre et Marie Curie (Paris 6) , Université Paris Diderot—Paris 7
摘要： Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to be studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).
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公开(公告)号：US10974080B2
公开(公告)日：2021-04-13
申请号：US15899076
申请日：2018-02-19
申请人： CARDIAWAVE , Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris , INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS- , Université Paris Diderot—Paris 7
发明人： Mickaël Tanter , Mathieu Pernot , Justine Robin
摘要： A method and system for secure ultrasound treatment of living tissues using an ultrasound probe comprising a reflective cavity in acoustic communication with living tissues, a transducer to emit an ultrasound wave in the reflective cavity and a transducer to acquire a backscattered signal in the reflective cavity. The method comprises the steps of a) emitting a first ultrasound wave in the reflective cavity that generates a backscattered ultrasound wave in the reflective cavity, b) acquiring a backscattered signal in the reflective cavity, c) determining whether an insonification can be safely performed by computing a similarity value between the backscattered signal and a predefined reference signal, and d) if an insonification can be safely performed, treating the living tissues with a second ultrasound wave emitted in the reflective cavity. The second ultrasound wave is focused a target point of the living tissues and generates a pressure point resulting in cavitation at this target point.
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公开(公告)号：US11141130B2
公开(公告)日：2021-10-12
申请号：US15740727
申请日：2016-06-30
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
摘要： In order to obtain a predetermined ultrasonic wave field in a homogeneous internal part of a medium masked by an aberrating barrier, an ultrasonic lens is interposed between the emitting ultrasonic probe and the aberrating barrier. The ultrasonic lens is calculated by using a model of the medium comprising a mapping of ultrasonic wave propagation properties obtained from actual imaging of the medium such that when the ultrasound probe sends a predetermined ultrasonic wave, said predetermined wave generates the predetermined objective ultrasonic wave field in the medium.
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公开(公告)号：US20180192990A1
公开(公告)日：2018-07-12
申请号：US15740727
申请日：2016-06-30
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
CPC分类号： A61B8/0808 , A61B8/4272 , B06B3/04 , G10K11/30
摘要： In order to obtain a predetermined ultrasonic wave field in a homogeneous internal part of a medium masked by an aberrating barrier, an ultrasonic lens is interposed between the emitting ultrasonic probe and the aberrating barrier. The ultrasonic lens is calculated by using a model of the medium comprising a mapping of ultrasonic wave propagation properties obtained from actual imaging of the medium such that when the ultrasound probe sends a predetermined ultrasonic wave, said predetermined wave generates the predetermined objective ultrasonic wave field in the medium.
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公开(公告)号：US20180236271A1
公开(公告)日：2018-08-23
申请号：US15899076
申请日：2018-02-19
申请人： Cardiawave , Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris , INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , Université Paris Diderot - Paris 7
发明人： Mickaël Tanter , Mathieu Pernot , Justine Robin
CPC分类号： A61N7/02 , A61B8/4466 , A61B8/485 , A61B17/22004 , A61B17/22029 , A61B2017/00084 , A61B2017/00243 , A61B2017/00725 , A61B2017/00783 , A61B2017/22002 , A61B2017/22007 , A61B2017/22008 , A61B2017/22014 , A61B2017/22015 , A61B2017/22028 , A61N7/00 , A61N2007/0004 , A61N2007/0039 , A61N2007/0052 , A61N2007/0069
摘要： A method and system for secure ultrasound treatment of living tissues using an ultrasound probe comprising a reflective cavity in acoustic communication with living tissues, a transducer to emit an ultrasound wave in the reflective cavity and a transducer to acquire a backscattered signal in the reflective cavity. The method comprises the steps of a) emitting a first ultrasound wave in the reflective cavity that generates a backscattered ultrasound wave in the reflective cavity, b) acquiring a backscattered signal in the reflective cavity, c) determining whether an insonification can be safely performed by computing a similarity value between the backscattered signal and a predefined reference signal, and d) if an insonification can be safely performed, treating the living tissues with a second ultrasound wave emitted in the reflective cavity. The second ultrasound wave is focused a target point of the living tissues and generates a pressure pulse resulting in cavitation at this target point
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