公开(公告)号：US11952583B2

公开(公告)日：2024-04-09

申请号：US17283877

申请日：2019-09-19

申请人： NUNHEMS B.V.

发明人： Wim Vriezen

IPC分类号： C12N15/82 ,  C12N9/12

CPC分类号： C12N15/8279 ,  C12N9/1205 ,  C12Y207/01039

摘要： The invention relates to lettuce plants comprising in its genome a mutant homoserine kinase allele in homozygous form, whereby the plants are resistant against Bremia lactucae.

公开(公告)号：US20130236934A1

公开(公告)日：2013-09-12

申请号：US13790589

申请日：2013-03-08

申请人： NOVUS INTERNATIONAL INC.

发明人： Ming Kang ,  Muralidhar Tata ,  Sridhar Vakalapudi ,  Patrick McLaughlin ,  Yingjie Ma ,  Aditya Mahajan ,  David Wickard ,  Stephen Lorbert ,  Friedhelm Brinkhaus ,  James C. Peterson

IPC分类号： C12P13/06

CPC分类号： C12P13/06 ,  C12N9/0006 ,  C12N9/1205 ,  C12N9/1217 ,  C12N9/88 ,  C12Y101/01003 ,  C12Y207/01039 ,  C12Y207/02004 ,  C12Y401/01031

摘要： The present invention encompasses a recombinant bacterium that is capable of producing L-homoserine and methods of using the bacterium for producing L-homoserine.

摘要翻译： 本发明包括能够产生L-高丝氨酸的重组细菌和使用该细菌产生L-高丝氨酸的方法。

公开(公告)号：US20230279421A1

公开(公告)日：2023-09-07

申请号：US18023815

申请日：2020-09-01

申请人： Enza Zaden Beheer B.V.

发明人： Bart Kaij ,  Yusuf Sen ,  Quy Dung Dinh

IPC分类号： C12N15/82 ,  A01H6/34 ,  C12N9/12 ,  A01H5/08

CPC分类号： C12N15/8282 ,  A01H6/348 ,  C12N9/1205 ,  C12Y207/01039 ,  A01H5/08

摘要： The present disclosure relates to squash plants that are resistant to the plant disease downy mildew caused by the pathogen Pseudoperonospora cubensis and/or powdery mildew caused by the pathogen Erysiphe cichoracearum. Specifically, the present disclosure relates to squash plants that are resistant to mildew disease including a mutated homoserine kinase gene encoding a mutated homoserine kinase protein. The present disclosure further relates to seeds, tissues, cells, or plant parts of the present squash plants, and to methods for identifying mildew resistant squash plants.

公开(公告)号：US5939307A

公开(公告)日：1999-08-17

申请号：US902336

申请日：1997-07-29

申请人： Ming-Der Wang ,  Jill S. Bradshaw ,  Stacia L. Swisher ,  Hungming James Liaw ,  Paul D. Hanke ,  Thomas P. Binder

发明人： Ming-Der Wang ,  Jill S. Bradshaw ,  Stacia L. Swisher ,  Hungming James Liaw ,  Paul D. Hanke ,  Thomas P. Binder

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N15/52 ,  C12P13/08 ,  C12R1/19 ,  C12N1/20

CPC分类号： C12Y101/01003 ,  C12N15/52 ,  C12P13/08 ,  C12Y207/01039 ,  C12Y207/02004 ,  C12Y402/03001

摘要： The present invention relates to novel strains of Escherichia coli and fermentation processes involving these microorganisms. More specifically, the present invention relates to genetically-modified Escherichia coli strains and the use thereof for the production of the amino acids, particularly members of the aspartate family of amino acids such as threonine. The present invention also relates to methods of preparing E. coli strains for use in the fermentative production of amino acids.

摘要翻译： 本发明涉及大肠杆菌的新菌株和涉及这些微生物的发酵方法。 更具体地，本发明涉及遗传修饰的大肠杆菌菌株及其用于生产氨基酸，特别是天冬氨酸家族氨基酸家族如苏氨酸的成员的用途。 本发明还涉及制备用于发酵生产氨基酸的大肠杆菌菌株的方法。

公开(公告)号：US20240301439A1

公开(公告)日：2024-09-12

申请号：US18597524

申请日：2024-03-06

申请人： NUNHEMS B.V.

发明人： Wim VRIEZEN

IPC分类号： C12N15/82 ,  C12N9/12

CPC分类号： C12N15/8279 ,  C12N9/1205 ,  C12Y207/01039

摘要： The invention relates to lettuce plants comprising in its genome a mutant homoserine kinase allele in homozygous form, whereby the plants are resistant against Bremia lactucae.

公开(公告)号：US20170137853A1

公开(公告)日：2017-05-18

申请号：US15316475

申请日：2015-06-05

申请人： CJ CHEILJEDANG CORPORATION

发明人： Jee Yeon BAE ,  Hyun Ah KIM ,  Yong Uk SHIN ,  So Young KIM ,  Sang Kyoum KIM ,  Kwang Ho NA ,  Ju Hee SEO ,  Sung Kwang SON ,  Hye Ryun YOO ,  Jin Geun CHOI

IPC分类号： C12P13/06 ,  C12N9/02 ,  C12N9/12 ,  C12N9/10 ,  C12N15/52 ,  C12N9/88

CPC分类号： C12P13/06 ,  C07K14/245 ,  C12N9/0008 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1205 ,  C12N9/1217 ,  C12N9/88 ,  C12N15/52 ,  C12P13/02 ,  C12R1/12 ,  C12Y102/01011 ,  C12Y203/01031 ,  C12Y206/01001 ,  C12Y207/01039 ,  C12Y207/02004 ,  C12Y401/01031 ,  C12Y402/01022

摘要： The present disclosure relates to a microorganism producing O-acetylhomoserine with high efficiency and a method for producing O-acetylhomoserine and L-methionine using the microorganism. The present disclosure provides a microorganism producing O-acetylhomoserine having an enhanced activity of a protein which is predicted to export O-acetylhomoserine, and a method for producing O-acetylhomoserine and L-methionine using the microorganism.

公开(公告)号：US20170101655A1

公开(公告)日：2017-04-13

申请号：US14901532

申请日：2015-06-22

申请人： CJ CHEILJEDANG CORPORATION

发明人： Hyun Ah KIM ,  Ju Hee SEO ,  Yong Uk SHIN ,  So Young KIM ,  Sang Kyoum KIM ,  Kwang Ho NA ,  Jee Yeon BAE ,  Sung Kwang SON ,  Hye Ryun YOO ,  Jin Geun CHOI

IPC分类号： C12P13/06

CPC分类号： C12P13/06 ,  C12N9/1029 ,  C12N9/1205 ,  C12N9/88 ,  C12N15/52 ,  C12Y203/01031 ,  C12Y203/03001 ,  C12Y207/01039 ,  C12Y401/01031

摘要： Disclosed is a microorganism of Escherichia sp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the microorganism.