公开(公告)号：US11510906B1

公开(公告)日：2022-11-29

申请号：US16811135

申请日：2020-03-06

Applicant: Clemson University

Inventor： Daniel C. Whitehead ,  James C. Morris ,  Chandima J. Narangoda

IPC: A61K31/4196 ,  A61P33/02 ,  A61K31/502

Abstract: A drug product and method for treating a parasitic disease in a host is described. The drug product comprises:
a carrier matrix; and
a drug substance having the formula: wherein:
R1 is selected from the group consisting of H, aliphatic of 1 to 100 carbons and arene comprising up to 100 carbons;
each R3 is independently selected from the group consisting of H, aliphatic of 1 to 100 carbons and arene comprising up to 100 carbons;
Y represents those elements necessary to form a 5 or 6 membered ring;
X is selected from the group consisting of B, O, N, S, Se and P; and
n is 1-4 as necessary to complete the valence of X.

公开(公告)号：US20150290344A1

公开(公告)日：2015-10-15

申请号：US14683775

申请日：2015-04-10

Applicant: Clemson University ,  College of Charleston

Inventor： Frank Alexis ,  Daniel C. Whitehead ,  Brooke A. Van Horn

IPC: A61K49/04 ,  C08L67/04 ,  A61L31/18 ,  A61L17/14 ,  A61L29/08 ,  A61L29/18 ,  A61L27/50 ,  A61L27/34 ,  C08G63/91 ,  A61L31/10

CPC classification number: A61K49/0442 ,  A61L17/145 ,  A61L27/34 ,  A61L27/50 ,  A61L29/085 ,  A61L29/18 ,  A61L31/10 ,  A61L31/18 ,  A61L2300/44 ,  C08G63/08 ,  C08G63/91 ,  C08G63/912 ,  C08L67/04 ,  C08L101/00

Abstract: Biodegradable, radio-opaque polyesters and poly(ester amides) are described herein. The polyesters contain a plurality of radio-opaque agents or radio-opaque agent-containing moieties that are covalently bound along or from the polymer backbone. The agents/moieties may be bound to the termini of the polymer provided they are bound within the polyester backbone as well. The polyester can be aliphatic or aromatic. The polyester and poly(ester amide) is substituted with a plurality of radio-opaque graft agents or prepared from an appropriate radio-opaque monomer agent. The materials can be used for any application where a radio-opaque material is desired or necessary. The materials can be used to form, in whole or in part, a medical device, or coating thereon or therein.

Abstract translation: 可生物降解的，不透射线的聚酯和聚（酯酰胺）在本文中描述。 聚酯包含多个不透射线剂或含聚合物主链共价键共价结合的不透射线剂。 所述试剂/部分可以结合到聚合物的末端，只要它们在聚酯骨架内结合即可。 聚酯可以是脂肪族或芳族的。 聚酯和聚（酯酰胺）被多个不透射线的接枝剂取代或者由适当的不透射线的单体剂制备。 这些材料可用于需要或不需要不透射线材料的任何应用。 这些材料可以全部或部分地用于形成医疗装置，或其上或其上的涂层。

公开(公告)号：US20240409842A1

公开(公告)日：2024-12-12

申请号：US18734086

申请日：2024-06-05

Applicant: CLEMSON UNIVERSITY

Inventor： Daniel C. Whitehead ,  Carlos D. Garcia ,  Ezequiel Martin Vidal

IPC: C11B3/10 ,  B01J20/24

Abstract: Methods and compositions are described that are useful for the refinement of animal or plant based fats or oils, such as rendered animal fats or used cooking oils. The methods can be utilized to remove metal and inorganic contaminants from the fats or oils. Refined products of the methods can be used to produce biodiesel that is compliant with ASTM B6751 for B100, and D7467 for B6 to B20.

公开(公告)号：US20160220952A1

公开(公告)日：2016-08-04

申请号：US15012991

申请日：2016-02-02

Applicant: CLEMSON UNIVERSITY

Inventor： Daniel C. Whitehead ,  Frank Alexis

IPC: B01D53/72 ,  B01D53/81

CPC classification number: B01D53/72 ,  B01D15/00 ,  B01D53/02 ,  B01D53/82 ,  B01D2251/21 ,  B01D2253/202 ,  B01D2253/25 ,  B01D2257/556 ,  B01D2257/708 ,  B01D2258/02 ,  B01D2258/0266 ,  B01D2258/0275

Abstract: Contaminant treatment methods and systems are described. Methods utilize biodegradable, non-toxic materials that can carry one or more functionalities useful for the remediation of fluids such as liquid or gaseous waste streams, chemical spills, etc. The carrier materials carry one or more functional groups that can target particular contaminants of a fluid for removal and/or modification to a more benign form. Targeted contaminants can include components of gaseous and/or liquids such as, and without limitation, gaseous discharges including VOCs and potentially hazardous contaminants such as organophosphorous compounds.

Abstract translation: 描述污染物处理方法和系统。 方法采用可生物降解的无毒材料，其可承载一种或多种可用于修复液体或气体废物流，化学物质泄漏等流体的功能。载体材料携带一个或多个可靶向特定污染物的官能团 用于去除和/或修饰成更良性形式的流体。 目标污染物可以包括气体和/或液体的组分，例如但不限于包括VOC和潜在的有害污染物如有机磷化合物的气体排放物。