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    Imaging-Guided Delivery of X-Ray Radiation
    1.
    发明申请
    Imaging-Guided Delivery of X-Ray Radiation 有权
    成像导向X射线辐射

    公开(公告)号：US20140348297A1

    公开(公告)日：2014-11-27

    申请号：US14457250

    申请日：2014-08-12

    申请人： CONVERGENT R.N.R LTD

    发明人： Zeev BURSHTEIN ,  Zeev HAREL ,  Aharon BAR-DAVID ,  Donald M. Korn

    IPC分类号： A61N5/10 ,  G21K1/04 ,  G21K1/06 ,  A61B6/00

    CPC分类号： A61N5/1049 ,  A61B6/06 ,  A61B6/4021 ,  A61B6/4035 ,  A61B6/483 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1054 ,  A61N2005/1061 ,  A61N2005/1091 ,  A61N2005/1095 ,  G21K1/04 ,  G21K1/065 ,  G21K1/067 ,  G21K2201/064 ,  H05G1/70

    摘要： An X-ray system comprises: (a) a source providing an X-ray diverging beam having treatment and imaging angular portions; (b) one or more lenses transforming the treatment portion of the X-ray beam into a converging beam directed to a target; (c) a first shutter located between the X-ray source and the target in the imaging portion of the X-ray radiation; the first shutter being selectively openable such that imaging portion of X-ray beam reaches the target; and (d) a detector configured to detect at least a portion of the imaging radiation after the imaging radiation has interacted with the target to provide imaging information of the target.

    摘要翻译： X射线系统包括：（a）提供具有处理和成像角部分的X射线发散光束的光源; （b）一个或多个透镜将X射线束的处理部分转换成指向靶的会聚光束; （c）在X射线辐射的成像部分中位于X射线源和靶之间的第一快门; 所述第一挡板选择性地可打开，使得X射线束的成像部分到达所述目标; 以及（d）检测器，被配置为在所述成像辐射已经与所述目标物体相互作用之后检测所述成像辐射的至少一部分，以提供所述目标的成像信息。

    X-RAY REFLECTIVE LENS ARRANGEMENT
    6.
    发明申请
    X-RAY REFLECTIVE LENS ARRANGEMENT 有权

    公开(公告)号：US20210193345A1

    公开(公告)日：2021-06-24

    申请号：US17196340

    申请日：2021-03-09

    申请人： CONVERGENT R.N.R LTD.

    发明人： Aharon BAR-DAVID ,  Zeev HAREL ,  Zeev BURSHTEIN

    IPC分类号： G21K5/04 ,  A61B6/00 ,  G21K1/06 ,  A61N5/10

    摘要： An X-ray lens arrangement for forming a radiation pattern as a focal track is disclosed. The pattern comprises at least one 3-dimensional focal track of radiation. The aforesaid lens arrangement has a main axis passing through intensity weighted centroids of the Xray source and the pattern. The lens arrangement includes at least one reflecting surface of continuously varying Rowland arcs. Each point belonging to the focal track is linked to each elemental point composing an emitting surface of said source by a corresponding Rowland arc.

    CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT
    7.
    发明申请
    CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT 审中-公开

    公开(公告)号：US20190175953A1

    公开(公告)日：2019-06-13

    申请号：US16258612

    申请日：2019-01-27

    申请人： CONVERGENT R.N.R LTD

    发明人： Aharon BAR-DAVID ,  Miri MARKOVICH ,  Zeev BURSHTEIN ,  Zeev HAREL

    IPC分类号： A61N5/10

    摘要： A method of a radiotherapy or radiosurgery treatment comprises steps of: (a) providing a converging x-ray beam source configured for emitting a converging X-ray beam propagating along an axis thereof; (b) emitting the converging x-ray beam towards a volume of treatment (VOT) having a length along the axis of the converging X-ray beam ranging between 2 mm and 5 cm within a patient's body such that a waist portion is within the VOT; (c) propagating the beam through tissues previously located relative to the VOT (PO); the VOT per se and tissues distally located to the VOT (DO). The converging X-ray beam characterized by a convergent angle ranging between 2 and 30 degrees providing 80% to 100% of a maximum dose is received by the VOT and less than 60% of the maximum dose is received by the PO and the DO.

    X-RAY OPTICAL ARRANGEMENT
    9.
    发明申请
    X-RAY OPTICAL ARRANGEMENT 有权

    公开(公告)号：US20220351874A1

    公开(公告)日：2022-11-03

    申请号：US17762477

    申请日：2020-09-23

    申请人： CONVERGENT R.N.R. LTD

    发明人： Shirly BORUKHIN ,  Michael KLECKNER ,  Aharon BAR-DAVID ,  Zeev HAREL

    IPC分类号： G21K1/06 ,  B23H7/02 ,  B23H9/00

    摘要： A method of manufacturing burr-edged reflecting tile elements for a mosaic X-ray lens configured for forming an X-ray beam comprises steps of: (a) providing a single crystal having first and second faces thereof being parallel therebetween; single crystal having crystallographic planes thereof being parallel to first and second faces of the single crystal; the first face dedicated for reflecting an X-ray beam to be incident thereto; (b) cutting the single crystal by means of a wire electrical discharging machine normally to the main faces. The step of cutting the single crystal comprises moving a wire within a cut in direction from the second face to the first face; such that burrs configured for reflecting the X-ray beam to be incident thereto are formed on edges of the cut.

    SYSTEM AND METHOD FOR OPTIMIZING RADIOTHERAPHY TREATMENTS
    10.
    发明申请
    SYSTEM AND METHOD FOR OPTIMIZING RADIOTHERAPHY TREATMENTS 有权

    公开(公告)号：US20220161060A1

    公开(公告)日：2022-05-26

    申请号：US17601868

    申请日：2020-04-07

    申请人： CONVERGENT R.N.R LTD.

    发明人： Asaf ZUCK ,  Zeev BURSHTEIN ,  Aharon BAR-DAVID ,  Zeev HAREL ,  Michael KLECKNER ,  Shirly BORUKHIN

    IPC分类号： A61N5/10 ,  A61K51/12 ,  A61K51/04

    摘要： A radiotherapy treatment system and method used for conducting radiographic X-ray imaging on a target organ during radiographic treatment. The system comprises (a) an x-ray beam source configurable to deliver an X-ray beam to a target organ, (b) optical means for converging and shaping said beam to a cone-shaped X-ray beam of photons which hit the target organ simultaneously, (c) multiple high-Z nanoparticles attachable to the target organ, said high-Z nanoparticles absorbing said X-ray radiation and emitting X-ray fluorescence (XRF) photons, (d) at least one XRF detector for detecting said XRF photons ejecting out of a patient's body, and (e) control means for controlling the radiotherapy treatment procedure.
    The x-ray beam is focusable on a section in the target organ where the concentration of said high-Z nanoparticles leading to a desirable emission of said XRF photons, and in case the emission of said XRF photons decreases, the x-ray beam is movable to refocus on the section in the target organ where the emission of said XRF photons is desirable.