利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

20 条记录 (耗时 0.011 秒)

    Means and methods for targeted x-ray therapy
    2.
    发明授权
    Means and methods for targeted x-ray therapy 有权

    公开(公告)号：US10265510B2

    公开(公告)日：2019-04-23

    申请号：US15503006

    申请日：2015-08-12

    申请人： CONVERGENT R.N.R LTD

    发明人： Zeev Harel ,  Zeev Burshtein ,  Aharon Bar-David ,  Miri Markovich

    IPC分类号： A61M37/00 ,  A61N5/10 ,  A61K41/00 ,  A61K9/00

    摘要： The present invention provides a method for activating a pro-drug in vivo comprising the steps of: (a) administering a pro-drag to a subject; (b) locating a target site which has been at least partially dosed with the pro-drug at a predetermined concentration; and (d) exposing the target site to X-ray radiation. The step of exposing the target site to X-ray radiation is characterized by providing a converging X-ray of a controllable waist, substantially uniform at the target site, sufficient to convert the pro-drug to an active drug, while the X-ray photon dosage at the target site is higher than the X-ray photon dosage at an adjacent non target site.

    Imaging-Guided Delivery of X-Ray Radiation
    5.
    发明申请
    Imaging-Guided Delivery of X-Ray Radiation 有权
    成像导向X射线辐射

    公开(公告)号：US20140348297A1

    公开(公告)日：2014-11-27

    申请号：US14457250

    申请日：2014-08-12

    申请人： CONVERGENT R.N.R LTD

    发明人： Zeev BURSHTEIN ,  Zeev HAREL ,  Aharon BAR-DAVID ,  Donald M. Korn

    IPC分类号： A61N5/10 ,  G21K1/04 ,  G21K1/06 ,  A61B6/00

    CPC分类号： A61N5/1049 ,  A61B6/06 ,  A61B6/4021 ,  A61B6/4035 ,  A61B6/483 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1054 ,  A61N2005/1061 ,  A61N2005/1091 ,  A61N2005/1095 ,  G21K1/04 ,  G21K1/065 ,  G21K1/067 ,  G21K2201/064 ,  H05G1/70

    摘要： An X-ray system comprises: (a) a source providing an X-ray diverging beam having treatment and imaging angular portions; (b) one or more lenses transforming the treatment portion of the X-ray beam into a converging beam directed to a target; (c) a first shutter located between the X-ray source and the target in the imaging portion of the X-ray radiation; the first shutter being selectively openable such that imaging portion of X-ray beam reaches the target; and (d) a detector configured to detect at least a portion of the imaging radiation after the imaging radiation has interacted with the target to provide imaging information of the target.

    摘要翻译： X射线系统包括：（a）提供具有处理和成像角部分的X射线发散光束的光源; （b）一个或多个透镜将X射线束的处理部分转换成指向靶的会聚光束; （c）在X射线辐射的成像部分中位于X射线源和靶之间的第一快门; 所述第一挡板选择性地可打开，使得X射线束的成像部分到达所述目标; 以及（d）检测器，被配置为在所述成像辐射已经与所述目标物体相互作用之后检测所述成像辐射的至少一部分，以提供所述目标的成像信息。

    X-RAY REFLECTIVE LENS ARRANGEMENT
    6.
    发明申请
    X-RAY REFLECTIVE LENS ARRANGEMENT 有权

    公开(公告)号：US20210193345A1

    公开(公告)日：2021-06-24

    申请号：US17196340

    申请日：2021-03-09

    申请人： CONVERGENT R.N.R LTD.

    发明人： Aharon BAR-DAVID ,  Zeev HAREL ,  Zeev BURSHTEIN

    IPC分类号： G21K5/04 ,  A61B6/00 ,  G21K1/06 ,  A61N5/10

    摘要： An X-ray lens arrangement for forming a radiation pattern as a focal track is disclosed. The pattern comprises at least one 3-dimensional focal track of radiation. The aforesaid lens arrangement has a main axis passing through intensity weighted centroids of the Xray source and the pattern. The lens arrangement includes at least one reflecting surface of continuously varying Rowland arcs. Each point belonging to the focal track is linked to each elemental point composing an emitting surface of said source by a corresponding Rowland arc.

    CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT
    7.
    发明申请
    CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT 审中-公开

    公开(公告)号：US20190175953A1

    公开(公告)日：2019-06-13

    申请号：US16258612

    申请日：2019-01-27

    申请人： CONVERGENT R.N.R LTD

    发明人： Aharon BAR-DAVID ,  Miri MARKOVICH ,  Zeev BURSHTEIN ,  Zeev HAREL

    IPC分类号： A61N5/10

    摘要： A method of a radiotherapy or radiosurgery treatment comprises steps of: (a) providing a converging x-ray beam source configured for emitting a converging X-ray beam propagating along an axis thereof; (b) emitting the converging x-ray beam towards a volume of treatment (VOT) having a length along the axis of the converging X-ray beam ranging between 2 mm and 5 cm within a patient's body such that a waist portion is within the VOT; (c) propagating the beam through tissues previously located relative to the VOT (PO); the VOT per se and tissues distally located to the VOT (DO). The converging X-ray beam characterized by a convergent angle ranging between 2 and 30 degrees providing 80% to 100% of a maximum dose is received by the VOT and less than 60% of the maximum dose is received by the PO and the DO.

    X-RAY REFLECTIVE LENS ARRANGEMENT
    9.
    发明申请
    X-RAY REFLECTIVE LENS ARRANGEMENT 有权
    X射线反射镜

    公开(公告)号：US20150248942A1

    公开(公告)日：2015-09-03

    申请号：US14430683

    申请日：2013-09-01

    申请人： CONVERGENT R.N.R. LTD

    发明人： Aharon Bar-David ,  Zeev Burshtein ,  Zeev Harel

    IPC分类号： G21K1/06

    CPC分类号： G21K1/062 ,  A61N5/1042 ,  A61N5/1084 ,  A61N2005/1091 ,  A61N2005/1095 ,  G21K5/04 ,  G21K2201/064

    摘要： An X-ray lens arrangement for forming a radiation pattern as a focal track is disclosed. The pattern comprises at least one 3-dimensional focal track of radiation. The aforesaid lens arrangement has a main axis passing through intensity weighted centroids of the X-ray source and the pattern. The lens arrangement includes at least one reflecting surface of continuously varying Rowland arcs. Each point belonging to the focal track is linked to each elemental point composing an emitting surface of said source by a corresponding Rowland arc.

    摘要翻译： 公开了一种用于形成辐射图案作为焦点轨迹的X射线透镜装置。 该图案包括至少一个辐射的三维焦点轨迹。 上述透镜装置具有通过X射线源的强度加权质心和图案的主轴。 透镜装置包括连续变化的罗兰弧的至少一个反射表面。 属于焦点轨迹的每个点通过相应的罗兰弧连接到构成所述源的发射表面的每个元素点。