公开(公告)号：US20110136118A1

公开(公告)日：2011-06-09

申请号：US12996403

申请日：2009-06-16

Applicant: Carol Kreader ,  Brian Ward

Inventor： Carol Kreader ,  Brian Ward

IPC: C12Q1/68

CPC classification number: C12Q1/6823 ,  C12Q1/6851 ,  C12Q2561/113 ,  C12Q2561/109 ,  C12Q2537/149 ,  C12Q2521/301 ,  C12Q2565/1015 ,  C12Q2525/161 ,  C12Q2525/131

Abstract: Provided are methods and kits for detecting amplification of a target nucleic acid during a real time quantitative polymerase chain reaction process using a universal detection system. The detection system uses an unlabeled probe that detects the amplified target nucleic acid and interacts with a universal detection module.

Abstract translation: 提供了用于在使用通用检测系统的实时定量聚合酶链反应过程中检测靶核酸的扩增的方法和试剂盒。 检测系统使用检测扩增的靶核酸并与通用检测模块相互作用的未标记的探针。

公开(公告)号：USD909782S1

公开(公告)日：2021-02-09

申请号：US29655001

申请日：2018-06-29

Applicant: Anthony Harcup ,  Richard Peter John Nicholas ,  Brian Ward

Designer： Anthony Harcup ,  Richard Peter John Nicholas ,  Brian Ward

公开(公告)号：US20170140396A1

公开(公告)日：2017-05-18

申请号：US15353479

申请日：2016-11-16

Applicant: Martha Amram ,  Sandra Carrico ,  Brian Ward ,  David Nelson ,  Trista Chen ,  David Smith

Inventor： Martha Amram ,  Sandra Carrico ,  Brian Ward ,  David Nelson ,  Trista Chen ,  David Smith

IPC: G06Q30/02 ,  G06Q50/06

CPC classification number: G06Q30/0201 ,  G06Q50/06

Abstract: A computer-implemented method for identifying utility usage from a historical utility file is disclosed. The method includes obtaining a file containing historical utility consumption of a dwelling over a time period; processing the file through optical character recognition (OCR); identifying contextual data from the OCR processed file; identifying chart data from the OCR processed file; extracting one or more values from the chart data, wherein the values correspond to one or more elements of the chart data; and contextualizing the extracted values from the chart data by applying the contextual data to the extracted value to obtain utility usage data.

公开(公告)号：US20130032346A1

公开(公告)日：2013-02-07

申请号：US13367106

申请日：2012-02-06

Applicant: Richard S. Wheeler ,  Chandler C. Newhall ,  Roger R. Myers ,  Brian Ward ,  Brian B. Beall ,  Harold D. Brannon

Inventor： Richard S. Wheeler ,  Chandler C. Newhall ,  Roger R. Myers ,  Brian Ward ,  Brian B. Beall ,  Harold D. Brannon

IPC: E21B43/267 ,  C09K8/94 ,  C09K8/80 ,  E21B43/26 ,  C09K8/70

CPC classification number: E21B43/267 ,  C09K8/703 ,  C09K8/80 ,  C09K2208/30

Abstract: In a method of hydraulically fracturing a hydrocarbon-bearing subterranean formation, a proppant stage is introduced into the fracture which contains a gaseous fluid and an ultra lightweight proppant suspended in a viscosified aqueous fluid. The gaseous fluid of the proppant stage contains at least about 90 volume percent of the combination of gaseous fluid and aqueous fluid. A pad fluid may first be introduced into the formation, the pad fluid containing a gaseous fluid and, optionally, an aqueous fluid. The gaseous fluid of the pad fluid mixture typically contains at least 70 volume percent of the mixture.

Abstract translation: 在含烃地层的水力压裂方法中，将支撑剂阶段引入含有气态流体的裂缝和悬浮在粘稠水溶液中的超轻质支撑剂。 支撑剂阶段的气态流体含有至少约90体积％的气态流体和含水流体的组合。 衬垫流体可以首先被引入到地层中，衬垫流体含有气体流体和任选的含水流体。 衬垫流体混合物的气体流体通常含有至少70体积％的混合物。

公开(公告)号：US20120021936A1

公开(公告)日：2012-01-26

申请号：US13124362

申请日：2009-10-14

Applicant: Brian Ward ,  Momar Ndao ,  Takol Chareonsirisuthikul ,  Sukathida Ubol

Inventor： Brian Ward ,  Momar Ndao ,  Takol Chareonsirisuthikul ,  Sukathida Ubol

IPC: C12Q1/70 ,  C40B30/04

CPC classification number: G01N33/56983 ,  G01N2333/185 ,  G01N2800/56 ,  Y02A50/53 ,  Y02A90/26

Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying dengue status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with dengue or not infected with dengue. The biomarkers can be detected by SELDI mass spectrometry.

Abstract translation: 本发明提供了可用于限定患者登革热状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，本发明的生物标志物可用于分类感染登革热或未感染登革热的受试者样品。 生物标志物可以通过SELDI质谱检测。

公开(公告)号：US20050260691A1

公开(公告)日：2005-11-24

申请号：US11006119

申请日：2004-12-06

Applicant: Momar Ndao ,  Brian Ward ,  Rebecca Caffrey ,  Terence Spithill ,  Hongshan Li ,  Vladimir Podust ,  Regis Perichon

Inventor： Momar Ndao ,  Brian Ward ,  Rebecca Caffrey ,  Terence Spithill ,  Hongshan Li ,  Vladimir Podust ,  Regis Perichon

IPC: A61B20060101 ,  C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  G01N33/569 ,  G01N33/68 ,  G06F19/00

CPC classification number: G01N33/56905 ,  C12Q1/6883 ,  C12Q1/6893 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/6893 ,  G01N2333/4716 ,  G01N2333/52 ,  G01N2333/775 ,  G01N2333/78 ,  G01N2333/9121 ,  Y02A90/26

Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Chagas disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with Chagas disease or non-infected. The biomarkers can be detected by SELDI mass spectrometry.

Abstract translation: 本发明提供了可用于限定患者中的恰加斯病状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，本发明的生物标志物可用于分类感染了恰加斯病或未感染的受试者样品。 生物标志物可以通过SELDI质谱检测。

公开(公告)号：US20050152919A1

公开(公告)日：2005-07-14

申请号：US10941634

申请日：2004-09-15

Applicant: Brian Ward ,  David Burt ,  Sophie Chabot

Inventor： Brian Ward ,  David Burt ,  Sophie Chabot

IPC: A61K39/165 ,  A61K39/295 ,  A61K39/39 ,  A61P31/14 ,  C07K16/10 ,  A61K31/739

CPC classification number: C07K16/1027 ,  A61K39/12 ,  A61K39/165 ,  A61K39/39 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/541 ,  A61K2039/543 ,  A61K2039/55511 ,  A61K2039/55516 ,  A61K2039/55572 ,  C12N2760/18434

Abstract: Compositions and methods for making and using therapeutic formulations of measles virus antigens with a Proteosome-based adjuvant are provided. The measles virus antigens may be derived from a variety of sources, such as from recombinant production or from a split antigen preparation. The measles vaccine formulations may be used, for example, in methods for treating or preventing a measles virus infection and eliciting a protective immune response.

Abstract translation: 提供了制备和使用具有基于蛋白酶体佐剂的麻疹病毒抗原治疗制剂的组合物和方法。 麻疹病毒抗原可以衍生自多种来源，例如来自重组生产或来自裂解抗原制备物。 麻疹疫苗制剂可用于例如治疗或预防麻疹病毒感染和引发保护性免疫应答的方法。

公开(公告)号：US06902914B2

公开(公告)日：2005-06-07

申请号：US10002292

申请日：2001-11-15

Applicant: Brian Ward ,  Leanne M. Snyder ,  Chuan Li ,  Keming Song ,  Kristen E. Opper ,  Stephanie Uder ,  Ron Hernan

Inventor： Brian Ward ,  Leanne M. Snyder ,  Chuan Li ,  Keming Song ,  Kristen E. Opper ,  Stephanie Uder ,  Ron Hernan

IPC: C12N15/66 ,  C12Q1/68 ,  C12P19/34 ,  C07H21/04

CPC classification number: C12N15/66 ,  C12Q1/6846 ,  C12Q2525/125 ,  C12Q2521/319

Abstract: Amplification mixtures, kits, amplicons, kits and processes are provided for amplifying a nucleic acid. In particular, provided are processes which utilize an amplification mixture comprising a polymerase, a deoxynucleotidetriphosphate (dNTP) mixture which contains modified dNTPs, a first primer and a second primer. Further provided are dNTP mixtures which contain modified dNTPs for at least two of the four nucleotide triphosphates, which when incorporated into a polynucelotide, impart resistance to enzymatic degradation by an exonuclease at the sites of incorporation of the modified dNTPs. Also provided are the amplicons and vectors which incorporate the modified nucleotides.

Abstract translation: 提供扩增混合物，试剂盒，扩增子，试剂盒和方法用于扩增核酸。 特别地，提供了利用包含聚合酶，含有修饰的dNTP的脱氧核苷三磷酸（dNTP）混合物，第一引物和第二引物的扩增混合物的方法。 还提供了dNTP混合物，其含有用于四种核苷酸三磷酸中的至少两种的修饰的dNTP，当掺入多聚苷中时，其在掺入修饰的dNTP的位点赋予外切核酸酶对酶降解的抗性。 还提供了掺入修饰的核苷酸的扩增子和载体。

公开(公告)号：USD490352S1

公开(公告)日：2004-05-25

申请号：US29186828

申请日：2003-07-22

Applicant: Brian Ward

Designer： Brian Ward

公开(公告)号：USD909268S1

公开(公告)日：2021-02-02

申请号：US29655004

申请日：2018-06-29

Applicant: Anthony Harcup ,  Richard Peter John Nicholas ,  Brian Ward

Designer： Anthony Harcup ,  Richard Peter John Nicholas ,  Brian Ward