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公开(公告)号：US07235354B2
公开(公告)日：2007-06-26
申请号：US10843944
申请日：2004-05-12
申请人： Casey C. Case , Lei Zhang , Fyodor Urnov
发明人： Casey C. Case , Lei Zhang , Fyodor Urnov
CPC分类号： G01N33/5005 , C12N15/1055 , C12N15/1079 , C12N15/8216 , C12N15/8241 , C12N15/8243 , C12Q1/6897
摘要： The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
摘要翻译： 本发明提供了使用重组锌指蛋白调节基因表达的方法，用于功能基因组学和靶标验证应用。
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公开(公告)号：US06777185B2
公开(公告)日：2004-08-17
申请号：US09925796
申请日：2001-08-09
申请人： Casey C. Case , Lei Zhang , Fyodor Urnov
发明人： Casey C. Case , Lei Zhang , Fyodor Urnov
IPC分类号： C12Q168
CPC分类号： G01N33/5005 , C12N15/1055 , C12N15/1079 , C12N15/8216 , C12N15/8241 , C12N15/8243 , C12Q1/6897
摘要： The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
摘要翻译： 本发明提供了使用重组锌指蛋白调节基因表达的方法，用于功能基因组学和靶标验证应用。
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公开(公告)号：US08586526B2
公开(公告)日：2013-11-19
申请号：US13068735
申请日：2011-05-17
申请人： Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
发明人： Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
CPC分类号： C12N15/907 , A61K38/00 , C07K14/195 , C07K2319/80 , C12N9/22 , C12N15/52 , C12N15/62 , C12N15/8213 , C12N15/85 , C12Y301/21004
摘要： Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
摘要翻译： 本文公开了编码包含新的DNA结合结构域（包括TALE DNA结合结构域）的多肽，多核苷酸，细胞和生物体。 还公开了使用这些新的DNA结合结构域来调节内源细胞序列的基因表达和/或基因组编辑的方法。
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公开(公告)号：US20110301073A1
公开(公告)日：2011-12-08
申请号：US13068735
申请日：2011-05-17
申请人： Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
发明人： Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
IPC分类号： A61K38/02 , C07K19/00 , C12N9/16 , C12N5/071 , C12N5/04 , C12N1/21 , C07H21/00 , C12N1/19 , C12N5/10 , C12N1/15 , C12N1/13 , C12N1/11 , C07K14/00 , C12N1/16
CPC分类号： C12N15/907 , A61K38/00 , C07K14/195 , C07K2319/80 , C12N9/22 , C12N15/52 , C12N15/62 , C12N15/8213 , C12N15/85 , C12Y301/21004
摘要： Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
摘要翻译： 本文公开了编码包含新的DNA结合结构域（包括TALE DNA结合结构域）的多肽，多核苷酸，细胞和生物体。 还公开了使用这些新的DNA结合结构域来调节内源细胞序列的基因表达和/或基因组编辑的方法。
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公开(公告)号：US06599692B1
公开(公告)日：2003-07-29
申请号：US09395448
申请日：1999-09-14
申请人： Casey C. Case , Lei Zhang
发明人： Casey C. Case , Lei Zhang
IPC分类号： C12Q102
CPC分类号： G01N33/5005 , C12N15/1055 , C12N15/1079 , C12N15/8216 , C12N15/8241 , C12N15/8243 , C12Q1/6897
摘要： The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
摘要翻译： 本发明提供了使用重组锌指蛋白调节基因表达的方法，用于功能基因组学和靶标验证应用。
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6.发明公开公开(公告)号：US20240338071A1
公开(公告)日：2024-10-10
申请号：US18748987
申请日：2024-06-20
申请人： Lei Zhang , Youjean Cho , Daekun Kim , Ava Robinson , Yu Jiang Tham , Rajan Vaish , Andrés Monroy-Hernández
发明人： Lei Zhang , Youjean Cho , Daekun Kim , Ava Robinson , Yu Jiang Tham , Rajan Vaish , Andrés Monroy-Hernández
CPC分类号： G06F3/011 , G06F1/163 , G06T19/006
摘要： Described are virtual AR interfaces for generating a virtual rotational interface for the purpose of controlling connected IoT devices using the inertial measurement unit (IMU) of a portable electronic device. The IMU control application enables a user of a portable electronic device to activate a virtual rotational interface overlay on a display and adjust a feature of a connected IoT product by rotating a portable electronic device. The device IMU moves a slider on the virtual rotational interface. The IMU control application sends a control signal to the IoT product which executes an action in accordance with the slider position. The virtual rotational interface is presented on the display as a virtual object in an AR environment. The IMU control application detects the device orientation (in the physical environment) and in response presents a corresponding slider element on the virtual rotational interface (in the AR environment).
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公开(公告)号：USD998204S1
公开(公告)日：2023-09-05
申请号：US29850953
申请日：2022-08-24
申请人： Lei Zhang
设计人： Lei Zhang
摘要： FIG. 1 is a front and top perspective view of a flashlight, showing my new design;
FIG. 2 is a right side elevation view thereof;
FIG. 3 is a left side elevation view thereof;
FIG. 4 is a front elevation view thereof;
FIG. 5 is a rear elevation view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is an enlarged perspective view of detail “8” identified in FIG. 1; and,
FIG. 9 is an enlarged rear elevation view of detail “9” identified in FIG. 5.
The dashed broken lines in the drawings illustrate portions of the article and form no part of the claimed design. The dash-dot-dash broken lines in FIGS. 1, 5, 8, and 9 are for the purpose of depicting the enlarged views and form no part of the claimed design.-
8.发明授权公开(公告)号：US10684811B2
公开(公告)日：2020-06-16
申请号：US15856375
申请日：2017-12-28
申请人： Jason Monroe , Christopher S. Welch , Lei Zhang
发明人： Jason Monroe , Christopher S. Welch , Lei Zhang
IPC分类号： G06F3/14 , B60Q3/12 , B60Q1/50 , B60Q3/10 , B60K37/04 , B60R11/00 , B60R11/04 , B60R16/02 , B60Q3/80 , B60Q3/74 , B60Q3/51 , B60Q1/32 , B60Q3/233 , G06F3/0488 , G06F3/0482 , G06F3/0484 , B60K35/00
摘要： A vehicle includes at least one display and a central controller in signal communication with the at least one display. The central controller is configured to detect a plurality of unique user profiles associated with peripheral electronic user devices located within the vehicle, and to establish signal communication with the peripheral electronic user devices located within the vehicle.
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公开(公告)号：US10521179B2
公开(公告)日：2019-12-31
申请号：US15856344
申请日：2017-12-28
申请人： Jason Monroe , Christopher S. Welch , Lei Zhang
发明人： Jason Monroe , Christopher S. Welch , Lei Zhang
IPC分类号： G06F3/14 , B60Q3/80 , B60Q3/74 , B60Q3/51 , B60Q1/32 , B60Q3/233 , G06F3/0488 , G06F3/0482 , G06F3/0484 , B60Q3/10 , B60K37/04 , B60R11/00 , B60R11/04 , B60R16/02 , B60Q1/50 , B60Q3/12 , B60K35/00
摘要： A vehicle includes an interior cabin and a plurality of modular docking stations fixedly disposed in the interior cabin. Each modular docking station is configured to removably receive one or more modular components. The one or more modular components interchangeably connect to the plurality of modular docking stations to enable relocation of each modular component of the one or more modular components in a desired modular docking station of the plurality of docking stations.
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公开(公告)号：US10378365B2
公开(公告)日：2019-08-13
申请号：US14238626
申请日：2012-07-11
申请人： Feng Lin , Renji Zhang , Qianming Gong , Lei Zhang , Ting Zhang , Xiao Yuan , Wentao Yan
发明人： Feng Lin , Renji Zhang , Qianming Gong , Lei Zhang , Ting Zhang , Xiao Yuan , Wentao Yan
摘要： Disclosed is a turbine rotor device for a gas turbine, the turbine rotor device comprising a turbine rotor body, and a pre-stressed fiber-wound layer, wherein the pre-stressed fiber-wound layer is wound on the periphery of the turbine rotor body to exert a predetermined pre-loading force on the turbine rotor body. Additionally, a rotor, and a gas turbine and a turbine engine having the turbine rotor device are also provided.
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