Composition and method for the treatment of dysglucaemia
    4.
    发明申请
    Composition and method for the treatment of dysglucaemia 审中-公开
    用于治疗dysglucaemia的组合物和方法

    公开(公告)号:US20050070502A1

    公开(公告)日:2005-03-31

    申请号:US10953453

    申请日:2004-09-30

    摘要: Dysglucaemia is treated and/or prevented by the administration of granulated starch, enzymatically degraded and releasing reducing sugars at a rate, adjusted to the metabolism of the patient, suffering from dysglucaemia. For example nocturnal hypoglycaemia in diabetic patients is prevented by administering to said patients a granulate or tablets comprising granulated cornstarch, and preferably also heat treated cornstarch and a low calorie sweetener. The inventive granulation minimises the available surface area and retards the enzymatic degradation of the cornstarch and ensures a controlled, e.g. a substantially linear release of reducing sugars, such as glucose, and a stable blood glucose level during several hours. The granulate or tablets are low in calories and contain no free sugar.

    摘要翻译: 通过施用造粒淀粉来治疗和/或预防糖尿病,通过调节至患有糖尿病的患者代谢的速率,酶促降解和释放还原糖。 例如,通过向所述患者施用包含颗粒状玉米淀粉,优选还加热处理的玉米淀粉和低热量甜味剂的颗粒或片剂来防止糖尿病患者的夜间低血糖。 本发明的造粒使可用的表面积最小化并延缓了玉米淀粉的酶降解,并确保了受控的例如。 在数小时内基本上线性释放还原糖,如葡萄糖,稳定的血糖水平。 颗粒或片剂的热量低,不含游离糖。

    Composition and method for the treatment of dysglucaemia
    5.
    发明授权
    Composition and method for the treatment of dysglucaemia 失效
    用于治疗dysglucaemia的组合物和方法

    公开(公告)号:US06815433B2

    公开(公告)日:2004-11-09

    申请号:US10002417

    申请日:2001-10-25

    IPC分类号: A61K31715

    摘要: Dysglucaemia is treated and/or prevented by the administration of granulated starch, enzymatically degraded and releasing reducing sugars at a rate, adjusted to the metabolism of the patient, suffering from dysglucaemia. For example nocturnal hypoglycaemia in diabetic patients is prevented by administering to said patients a granulate or tablets comprising granulated cornstarch, and preferably also heat treated cornstarch and a low calorie sweetener. The inventive granulation minimizes the available surface area and retards the enzymatic degradation of the cornstarch and ensures a controlled, e.g. a substantially linear release of reducing sugars, such as glucose, and a stable blood glucose level during several hours. The granulate or tablets are low in calories and contain no free sugar.

    Composition and method for use in intestinal cleansing procedures
    6.
    发明申请
    Composition and method for use in intestinal cleansing procedures 审中-公开
    用于肠道清洁程序的组合物和方法

    公开(公告)号:US20050054611A1

    公开(公告)日:2005-03-10

    申请号:US10496901

    申请日:2003-09-12

    摘要: The nutritional deficiencies which constitute a serious side-effect of intestinal cleansing procedures can be alleviated or entirely avoided by a composition and method according to the present invention, wherein a complex carbohydrate is administered to the patient in a form and an amount which gives a blood glucose response similar to that following a normal meal, and stabilizes the blood glucose level above 3.5 mmol/l, preferably above about 4 mmol/l, thus preventing hypoglycaemia. The composition and method is suitable for all patients, but in particular for weakened, elderly or diabetic patients. The composition and method significantly improves the well-being of the patients, and does not reduce the cleansing effect achieved by conventional intestinal cleansing preparations or procedures, and has no known side effects. The preferred complex carbohydrate is native corn starch, and the composition may also include a simple carbohydrate, e.g. sucrose.

    摘要翻译: 构成肠道清洁程序的严重副作用的营养缺乏可以通过根据本发明的组合物和方法来缓解或完全避免,其中复合碳水化合物以给予血液的形式和量给予患者 葡萄糖反应类似于正常膳食后的血糖反应,并且将血糖水平稳定在高于3.5mmol / l,优选高于约4mmol / l,从而预防低血糖。 组合物和方法适用于所有患者,特别适用于弱化,老年或糖尿病患者。 组合物和方法显着改善患者的健康,并且不会降低通过常规肠道清洁制剂或程序实现的清洁效果,并且没有已知的副作用。 优选的复合碳水化合物是天然玉米淀粉,并且组合物还可以包括简单的碳水化合物,例如。 蔗糖。

    Medicinal use of IFG-II
    7.
    发明授权
    Medicinal use of IFG-II 失效
    药物使用IFG-II

    公开(公告)号:US5525593A

    公开(公告)日:1996-06-11

    申请号:US162019

    申请日:1994-01-26

    摘要: The use of IGF-II for preparing a medicament for the regeneration of muscle tissue; and methods for medical treatment for the purpose of regenerating muscle tissue, for minimizing scar formation during healing of a wound or for preventing undesired tissue adhesion after injury, such as after surgery.

    摘要翻译: PCT No.PCT / SE92 / 00397 Sec。 371日期1993年12月3日第 102(e)日期1994年1月26日PCT提交1992年6月11日PCT公布。 第WO92 / 22311号公报 日期:1992年12月23日。使用IGF-II制备用于肌肉组织再生的药物; 以及用于再生肌肉组织的目的的医疗处理方法,用于使伤口愈合期间的瘢痕形成最小化或者用于防止在损伤后例如手术后不期望的组织粘连。

    Composition and method for the treatment of dysglucaemia
    8.
    发明授权
    Composition and method for the treatment of dysglucaemia 失效
    用于治疗dysglucaemia的组合物和方法

    公开(公告)号:US06815436B2

    公开(公告)日:2004-11-09

    申请号:US10202870

    申请日:2002-07-26

    IPC分类号: A61K3115

    摘要: Dysglucaemia is treated and/or prevented by the administration of granulated starch, enzymatically degraded and releasing reducing sugars at a rate, adjusted to the metabolism of the patient, suffering from dysglucaemia. For example nocturnal hypoglycaemia in diabetic patients is prevented by administering to said patients a granulate or tablets comprising granulated cornstarch, and preferably also heat treated cornstarch and a low calorie sweetener. The inventive granulation minimises the available surface area and retards the enzymatic degradation of the cornstarch and ensures a controlled, e.g. a substantially linear release of reducing sugars, such as glucose, and a stable blood glucose level during several hours. The granulate or tablets are low in calories and contain no free sugar.

    摘要翻译: 通过施用造粒淀粉来治疗和/或预防糖尿病,通过调节至患有糖尿病的患者代谢的速率,酶促降解和释放还原糖。 例如,通过向所述患者施用包含颗粒状玉米淀粉,优选还加热处理的玉米淀粉和低热量甜味剂的颗粒或片剂来防止糖尿病患者的夜间低血糖。 本发明的造粒使可用的表面积最小化并延缓了玉米淀粉的酶降解,并确保了受控的例如。 在数小时内基本上线性释放还原糖,如葡萄糖,稳定的血糖水平。 颗粒或片剂的热量低,不含游离糖。