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    Delayed emission detection devices and methods
    2.
    发明授权
    Delayed emission detection devices and methods 有权
    延迟发射检测装置和方法

    公开(公告)号：US08536545B2

    公开(公告)日：2013-09-17

    申请号：US13228448

    申请日：2011-09-09

    申请人： Jigang Wu ,  Shuo Pang ,  Changhuei Yang

    发明人： Jigang Wu ,  Shuo Pang ,  Changhuei Yang

    IPC分类号： G01N21/64

    CPC分类号： G01N21/6458 ,  G01N15/1427

    摘要： Embodiments of the present invention relate to a delayed emission detection device comprising a time-gated illumination source configured to provide excitation light to fluorophore during an excitation period and a light detector configured to receive emissions released from the fluorophore during a collection period after the excitation period.

    摘要翻译： 本发明的实施例涉及延迟发射检测装置，其包括时间门控照明源，其被配置为在激发周期期间向荧光团提供激发光;以及光检测器，被配置为在激发周期之后的收集期间接收从荧光团释放的排放 。

    Holographically Illuminated Imaging Devices
    3.
    发明申请
    Holographically Illuminated Imaging Devices 有权
    全息照明成像设备

    公开(公告)号：US20110085219A1

    公开(公告)日：2011-04-14

    申请号：US12903650

    申请日：2010-10-13

    申请人： Changhuei Yang ,  Jigang Wu ,  Shuo Pang

    发明人： Changhuei Yang ,  Jigang Wu ,  Shuo Pang

    IPC分类号： G02B5/32

    CPC分类号： G02B27/106 ,  G02B5/32 ,  G02B21/0076 ,  G02B21/16 ,  G02B26/004 ,  G02B26/10 ,  G02B27/1093 ,  G02B27/141

    摘要： Embodiments of the present invention relate to holographically illuminated imaging devices including a holographic element for transforming an illumination beam into a focal array of light spots, a scanning mechanism for moving an object across one or more light spots in the focal array of light spots, and a light detector for detecting light associated with the focal array of light spots and generating light data associated with the received light.

    摘要翻译： 本发明的实施例涉及全息照明的成像装置，其包括用于将照明光束变换成光点的焦点阵列的全息元件，用于沿着光斑的焦点阵列中的一个或多个光点移动物体的扫描机构，以及 光检测器，用于检测与光点的焦点阵列相关联的光并产生与所接收的光相关联的光数据。

    PAIRED ANGLED ROTATION SCANNING PROBES AND METHODS OF USE
    4.
    发明申请
    PAIRED ANGLED ROTATION SCANNING PROBES AND METHODS OF USE 有权
    配对旋转扫描探测器和使用方法

    公开(公告)号：US20070066871A1

    公开(公告)日：2007-03-22

    申请号：US11535427

    申请日：2006-09-26

    申请人： Changhuei Yang ,  Jigang Wu

    发明人： Changhuei Yang ,  Jigang Wu

    IPC分类号： A61B1/06

    CPC分类号： A61B5/6852 ,  A61B1/00096 ,  A61B1/00172 ,  A61B5/0062 ,  A61B5/0066

    摘要： Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as to image a conical scan volume when light is provided by the source. Reflected light from a sample under investigation is collected by the fiber and analyzed by an imaging system. Such probes may be very compact, e.g., having a diameter 1 mm or less, and are advantageous for use in minimally invasive surgical procedures.

    摘要翻译： 探针，以及用于光学扫描探针前面的锥形体积的系统和方法，用于成像模态，例如光学相干断层扫描（OCT）。 探针包括具有近端和远端并限定轴线的光纤，光纤的近端靠近光源，并且远端具有第一倾斜表面。 折射透镜元件靠近光纤的远端定位。 透镜元件和光纤端都被构造为围绕轴线分开旋转，以便在由光源提供光时对圆锥扫描体积进行成像。 被研究样品的反射光由纤维收集并通过成像系统进行分析。 这种探针可以非常紧凑，例如具有1mm或更小的直径，并且有利于用于微创外科手术。

    High resolution imaging devices with wide field and extended focus
    5.
    发明授权
    High resolution imaging devices with wide field and extended focus 有权
    高分辨率成像设备，具有宽场和扩展对焦

    公开(公告)号：US09357202B2

    公开(公告)日：2016-05-31

    申请号：US13032529

    申请日：2011-02-22

    申请人： Sri Rama Prasanna Pavani ,  Changhuei Yang ,  Jigang Wu

    发明人： Sri Rama Prasanna Pavani ,  Changhuei Yang ,  Jigang Wu

    IPC分类号： H04N9/47 ,  H04N13/02 ,  G02B21/16 ,  G02B21/36 ,  G02B27/22

    CPC分类号： H04N13/207 ,  G02B21/16 ,  G02B21/361 ,  G02B27/2242 ,  G02B27/2285 ,  H04N13/221 ,  H04N13/254

    摘要： Embodiments of the present invention relate to a high-resolution imaging device with wide field and extended focus comprising a beam generator for generating a plurality of nondiffracting beams and a scanning mechanism for moving the plurality of nondiffracting beams relative to the object to illuminate a volume of the object. The high-resolution imaging device also comprises surface element and a body having a light detector layer outside the surface element. The light detector layer has a light detector configured to measure light data associated with the plurality of nondiffracting beams illuminating the volume of the object. In some cases, the high-resolution imaging device also includes a lens inside of the light detector layer. The lens is configured to focus the light on the light detector surface.

    摘要翻译： 本发明的实施例涉及一种具有广场和扩展焦点的高分辨率成像装置，包括用于产生多个非衍射光束的光束发生器和用于相对于物体移动多个非衍射光束的扫描机构， 物体。 高分辨率成像装置还包括表面元件和在表面元件外部具有光检测器层的主体。 光检测器层具有光检测器，其被配置为测量与照射物体的体积的多个非衍射光束相关联的光数据。 在一些情况下，高分辨率成像装置还包括在光检测器层内部的透镜。 镜头被配置为将光聚焦在光检测器表面上。

    Harmonically matched diffraction grating pair
    7.
    发明授权
    Harmonically matched diffraction grating pair 失效
    谐波匹配衍射光栅对

    公开(公告)号：US07609392B2

    公开(公告)日：2009-10-27

    申请号：US11770553

    申请日：2007-06-28

    申请人： Zahid Yaqoob ,  Jigang Wu ,  Marinko Sarunic ,  Changhuei Yang

    发明人： Zahid Yaqoob ,  Jigang Wu ,  Marinko Sarunic ,  Changhuei Yang

    IPC分类号： G01B9/02

    CPC分类号： G01B9/0201 ,  G01B9/02004 ,  G01B9/02081 ,  G01B9/0209 ,  G01B2290/30 ,  G01B2290/45

    摘要： A method and device realize shallow gratings-based planar beam splitter/combiner. Non-trivial phase shifts between different ports of resulting interferometers are used to acquire full-field phase measurements. The non-trivial phase shifts between different ports of the planar beam splitter/combiner can be adjusted by simply shearing one grating with respect to the second grating. The two shallow diffraction gratings are harmonically-related and can be recorded on a single substrate for compact interferometric based schemes. During the recording process, the two gratings are aligned such that the grating planes and the grating vectors are parallel to that of each other. The relative phase of the recording beams controls the shearing between the recorded harmonically-related shallow phase gratings. The relative shearing of the two gratings defines the non-trivial phase shift between different ports of the compact planar beam splitter/combiner.

    摘要翻译： 一种方法和装置实现了基于光栅的平面光束分离器/组合器。 所得干涉仪的不同端口之间的非平凡相移用于获取全场相位测量。 平面分束器/组合器的不同端口之间的非平凡相移可以通过相对于第二光栅简单地剪切一个光栅来调节。 两个浅衍射光栅是谐波相关的，并且可以记录在单个基板上，用于紧凑的基于干涉的方案。 在记录过程中，两个光栅对齐，使得光栅平面和光栅矢量彼此平行。 记录光束的相对相位控制记录的谐波相关浅相位光栅之间的剪切。 两个光栅的相对剪切定义了紧凑型平面分束器/组合器的不同端口之间的非平凡相移。

    Talbot-illuminated imaging devices, systems, and methods for focal plane tuning
    8.
    发明授权
    Talbot-illuminated imaging devices, systems, and methods for focal plane tuning 有权
    Talbot照明成像设备，系统和焦平面调谐方法

    公开(公告)号：US08946619B2

    公开(公告)日：2015-02-03

    申请号：US13451543

    申请日：2012-04-20

    申请人： Jigang Wu ,  Shuo Pang ,  Zheng Li ,  Guoan Zheng ,  Changhuei Yang

    发明人： Jigang Wu ,  Shuo Pang ,  Zheng Li ,  Guoan Zheng ,  Changhuei Yang

    IPC分类号： H01J5/16 ,  G02B21/08 ,  G02B21/00 ,  G02B21/24 ,  G02B21/36 ,  G02B27/42

    CPC分类号： G02B21/086 ,  G02B21/0044 ,  G02B21/244 ,  G02B21/361 ,  G02B27/4227

    摘要： A Talbot-illuminated imaging system for focal plane tuning, the device comprising a Talbot element, a tunable illumination source, a scanning mechanism, a light detector, and a processor. The element generate san array of focused light spots at a focal plane. The tunable illumination source shifts the focal plane to a plane of interest by adjusting a wavelength of light incident the Talbot element. The scanning mechanism scans an object across an array of focused light spots in a scanning direction. The light detector determines time-varying light data associated with the array of focused light spots as the object scans across the array of light spots. The processor constructs an image of the object based on the time-varying data.

    摘要翻译： 一种用于焦平面调谐的Talbot照明成像系统，该装置包括Talbot元件，可调谐照明源，扫描机构，光检测器和处理器。 该元素在聚焦平面上产生聚焦光斑的圣阵列。 可调谐照明源通过调节入射到Talbot元件的光的波长将焦平面移动到感兴趣的平面。 扫描机构沿扫描方向扫描聚焦光点阵列上的物体。 光检测器确定随着对象扫描光点阵列而与聚焦光点阵列相关联的时变光数据。 处理器基于时变数据构建对象的图像。

    HIGH RESOLUTION IMAGING DEVICES WITH WIDE FIELD AND EXTENDED FOCUS
    10.
    发明申请
    HIGH RESOLUTION IMAGING DEVICES WITH WIDE FIELD AND EXTENDED FOCUS 有权
    高分辨率成像装置，具有宽域和扩展焦点

    公开(公告)号：US20110205352A1

    公开(公告)日：2011-08-25

    申请号：US13032529

    申请日：2011-02-22

    申请人： Sri Rama Prasanna Pavani ,  Changhuei Yang ,  Jigang Wu

    发明人： Sri Rama Prasanna Pavani ,  Changhuei Yang ,  Jigang Wu

    IPC分类号： H04N7/18

    CPC分类号： H04N13/207 ,  G02B21/16 ,  G02B21/361 ,  G02B27/2242 ,  G02B27/2285 ,  H04N13/221 ,  H04N13/254

    摘要： Embodiments of the present invention relate to a high-resolution imaging device with wide field and extended focus comprising a beam generator for generating a plurality of nondiffracting beams and a scanning mechanism for moving the plurality of nondiffracting beams relative to the object to illuminate a volume of the object. The high-resolution imaging device also comprises surface element and a body having a light detector layer outside the surface element. The light detector layer has a light detector configured to measure light data associated with the plurality of nondiffracting beams illuminating the volume of the object. In some cases, the high-resolution imaging device also includes a lens inside of the light detector layer. The lens is configured to focus the light on the light detector surface.

    摘要翻译： 本发明的实施例涉及一种具有广场和扩展焦点的高分辨率成像装置，包括用于产生多个非衍射光束的光束发生器和用于相对于物体移动多个非衍射光束的扫描机构， 物体。 高分辨率成像装置还包括表面元件和在表面元件外部具有光检测器层的主体。 光检测器层具有光检测器，其被配置为测量与照射物体的体积的多个非衍射光束相关联的光数据。 在一些情况下，高分辨率成像装置还包括在光检测器层内部的透镜。 镜头被配置为将光聚焦在光检测器表面上。