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1.发明申请公开(公告)号：US20130157368A1
公开(公告)日：2013-06-20
申请号：US13331283
申请日：2011-12-20
申请人： Charito Buensuceso , Agnieszka Seyda , David C. Colter , Sridevi Dhanaraj , Brian C. Kramer , Jason Elliot Ekert , Amanda Lynn Kauffman
发明人： Charito Buensuceso , Agnieszka Seyda , David C. Colter , Sridevi Dhanaraj , Brian C. Kramer , Jason Elliot Ekert , Amanda Lynn Kauffman
IPC分类号： C12N5/071 , C12N15/867
CPC分类号： C12N15/86 , C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2506/25 , C12N2510/00
摘要： We have disclosed an induced pluripotent stem cell and the method of preparing the induced pluripotent stem cell from a human kidney-derived cell. More particularly, we have disclosed a human kidney-derived iPS cell which may be differentiated into cells of ectoderm, mesoderm, and endoderm lineages.
摘要翻译： 我们已经公开了诱导多能干细胞和从人肾源细胞制备诱导的多能干细胞的方法。 更具体地，我们已经公开了可以分化成外胚层，中胚层和内胚层谱系的细胞的人肾来源的iPS细胞。
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2.发明申请公开(公告)号：US20130157365A1
公开(公告)日：2013-06-20
申请号：US13330931
申请日：2011-12-20
IPC分类号： C12N5/071
CPC分类号： C12N5/0605 , C12N5/0696 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2506/025
摘要： We have disclosed an induced pluripotent stem cell and the method of preparing the induced pluripotent stem cell from a human umbilical cord tissue-derived cell. More particularly, we have disclosed a human umbilical cord tissue-derived iPS cell which may be differentiated into cells of ectoderm, mesoderm, and endoderm lineages.
摘要翻译： 我们已经公开了诱导多能干细胞和从人脐带组织来源的细胞制备诱导的多能干细胞的方法。 更具体地，我们已经公开了可以分化成外胚层，中胚层和内胚层谱系细胞的人脐带组织来源的iPS细胞。
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公开(公告)号：US20060153815A1
公开(公告)日：2006-07-13
申请号：US11304091
申请日：2005-12-15
申请人： Agnieszka Seyda , David Colter , Charito Buensuceso , Sridevi Dhanaraj , Anna Gosiewska , Jeffrey Geesin , Angelo Scopelianos
发明人： Agnieszka Seyda , David Colter , Charito Buensuceso , Sridevi Dhanaraj , Anna Gosiewska , Jeffrey Geesin , Angelo Scopelianos
CPC分类号： C12N5/0068 , A61L27/3604 , A61L27/38 , C12N2533/40
摘要： Tissue engineering devices for use in the repair or regeneration of tissue made of support scaffolds and cell sheets.
摘要翻译： 用于修复或再生由支撑支架和细胞片组成的组织的组织工程装置。
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公开(公告)号：US20120039855A1
公开(公告)日：2012-02-16
申请号：US13206715
申请日：2011-08-10
申请人： Roee Atlas , Israel Nur , Roberto Meidler , Liliana Bar , Charito Buensuceso , Anthony J. Kihm , Sridevi Dhanaraj
发明人： Roee Atlas , Israel Nur , Roberto Meidler , Liliana Bar , Charito Buensuceso , Anthony J. Kihm , Sridevi Dhanaraj
CPC分类号： A61L27/225 , A61L27/3834 , C12N2533/56
摘要： The invention relates to a fibrin-based scaffold suitable for supporting a population of cells comprising mesenchymal stem cells (MSC) and/or umbilical tissue derived cells (UTC) at the site of administration for a prolonged period of time. The scaffold is capable of supporting at least 1×106 cells/ml scaffold. The invention also relates to the preparation of the scaffold and to its use. Preparation of the scaffold is carried out with a fibrinogen component comprising fibrinogen having a final concentration of higher than 17.5 mg/ml scaffold. The scaffold and the embedded MSC and/or UTC can be used for increasing vascularization and/or wound healing at the site of administration.
摘要翻译： 本发明涉及一种适合于在给药部位长时间支持包含间充质干细胞（MSC）和/或脐带组织衍生细胞（UTC）的细胞群的基于纤维蛋白的支架。 支架能够支持至少1×10 6个细胞/ ml的支架。 本发明还涉及脚手架及其用途的制备。 用包含最终浓度高于17.5mg / ml支架的纤维蛋白原的纤维蛋白原组分进行支架的制备。 支架和嵌入式MSC和/或UTC可用于在给药部位增加血管形成和/或伤口愈合。
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5.发明授权Mammary artery derived cells and methods of use in tissue repair and regeneration 有权乳腺动脉来源的细胞和组织修复和再生中使用的方法公开(公告)号：US08323972B2
公开(公告)日：2012-12-04
申请号：US12885855
申请日：2010-09-20
CPC分类号： C12N5/069 , C12N5/0668 , C12N5/0692 , C12N2509/00
摘要： An isolated mammalian internal mammary artery-derived cell is disclosed. Furthermore, methods of isolating the mammalian internal mammary artery-derived cell are disclosed. The cell is useful in tissue engineering technologies, specifically in vascular tissue engineering.
摘要翻译： 公开了一种分离的哺乳动物内部乳腺动脉来源的细胞。 此外，公开了分离哺乳动物内部乳腺动脉的细胞的方法。 该细胞可用于组织工程技术，特别是在血管组织工程中。
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6.发明申请MAMMARY ARTERY DERIVED CELLS AND METHODS OF USE IN TISSUE REPAIR AND REGENERATION 有权主动脉导管细胞和组织修复和再生中使用的方法公开(公告)号：US20110076769A1
公开(公告)日：2011-03-31
申请号：US12885855
申请日：2010-09-20
IPC分类号： C12N5/071
CPC分类号： C12N5/069 , C12N5/0668 , C12N5/0692 , C12N2509/00
摘要： An isolated mammalian internal mammary artery-derived cell is disclosed. Furthermore, methods of isolating the mammalian internal mammary artery-derived cell are disclosed. The cell is useful in tissue engineering technologies, specifically in vascular tissue engineering.
摘要翻译： 公开了一种分离的哺乳动物内部乳腺动脉来源的细胞。 此外，公开了分离哺乳动物内部乳腺动脉的细胞的方法。 该细胞可用于组织工程技术，特别是在血管组织工程中。
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