Multi-mode signal offset in time-of-flight mass spectrometry
    1.
    发明授权
    Multi-mode signal offset in time-of-flight mass spectrometry 有权
    飞行时间质谱中的多模信号偏移

    公开(公告)号:US06794643B2

    公开(公告)日:2004-09-21

    申请号:US10349777

    申请日:2003-01-23

    IPC分类号: H01J4940

    CPC分类号: H01J49/0036

    摘要: A system and method of processing signals generated at a detector of a mass spectrometer prior to signal conversion in which a pre-ADC offset is applied to the signals that is adjustable in polarity and magnitude in accordance with a user-selected mode. According to a first mode, a positive offset is applied to the signals to improve quantitation accuracy and in a second mode, a negative offset is applied to the signals to improve resolution and mass assignment.

    摘要翻译: 在信号转换之前处理在质谱仪的检测器处产生的信号的系统和方法,其中根据用户选择的模式将前ADC偏移施加到可在极性和幅度上调节的信号。 根据第一模式,对信号施加正偏移以提高定量精度,并且在第二模式中,向信号施加负偏移以改善分辨率和质量分配。

    Mass spectrometry system having ion deflector
    2.
    发明授权
    Mass spectrometry system having ion deflector 有权
    具有离子偏转器的质谱系统

    公开(公告)号:US07633059B2

    公开(公告)日:2009-12-15

    申请号:US11580369

    申请日:2006-10-13

    IPC分类号: H01J49/26

    摘要: A tandem mass spectrometer and method for calibrating a tandem mass spectrometer. The tandem mass spectrometer comprises first and second mass analyzers. The first and second mass analyzers form an ion path. The second mass analyzer is positioned downstream from the first mass analyzer and is arranged to receive ions from the first mass analyzer. An electrode arrangement positioned between the first and second mass analyzers. The electrode assembly is configured to selectively deflect ions from the ion path.

    摘要翻译: 用于校准串联质谱仪的串联质谱仪和方法。 串联质谱仪包括第一和第二质量分析仪。 第一和第二质量分析器形成离子路径。 第二质量分析器位于第一质量分析器的下游,并被布置成接收来自第一质量分析器的离子。 位于第一和第二质量分析器之间的电极装置。 电极组件被配置为选择性地偏离离子离子。

    Method and apparatus for performance improvement of mass spectrometers
using dynamic ion optics
    3.
    发明授权
    Method and apparatus for performance improvement of mass spectrometers using dynamic ion optics 有权
    使用动态离子光学器件进行质谱仪性能改进的方法和装置

    公开(公告)号:US6153880A

    公开(公告)日:2000-11-28

    申请号:US410379

    申请日:1999-09-30

    IPC分类号: H01J49/42

    CPC分类号: H01J49/4215 H01J49/067

    摘要: A mass spectrometer method and apparatus improve resolution and sensitivity. A voltage supply is coupled to a mass filter for applying a radio frequency voltage and for operating at at least one selected frequency. An ion optical element such as an entrance lens is driven by a voltage supply that is phase coherent with the voltage applied to the mass filter. The ion beam is tailored so that the phase space relationship of the ions is more closely matched to the acceptance of the mass filter. The ions in the incoming beam are dynamically matched to the acceptance of the mass filter over each cycle of the voltage applied to the mass filter. The ion optical element may be a single entrance lens to which is applied only a single phase coherent voltage.

    摘要翻译: 质谱仪方法和设备提高分辨率和灵敏度。 电压源耦合到质量过滤器以施加射频电压并且以至少一个所选择的频率进行操作。 诸如入射透镜的离子光学元件由与施加到质量过滤器的电压相位相干的电压源驱动。 定制离子束,使得离子的相位空间关系与质量过滤器的接受度更接近。 入射束中的离子与施加到质量过滤器的电压的每个周期动态地匹配质量过滤器的接受。 离子光学元件可以是仅施加单相相干电压的单个入射透镜。

    Systems and methods for decreasing settling times in MS/MS
    4.
    发明授权
    Systems and methods for decreasing settling times in MS/MS 有权
    减少MS / MS沉降时间的系统和方法

    公开(公告)号:US08084733B2

    公开(公告)日:2011-12-27

    申请号:US12617028

    申请日:2009-11-12

    IPC分类号: H01J49/02

    CPC分类号: H01J49/0027 H01J49/004

    摘要: Systems and methods are provided for optimizing the performance of a mass spectrometer system when multiple measurements are made. For example, the total settling time of different components or stages of a mass spectrometer, such as a tandem mass spectrometer, are decreased by optimally ordering the measurements.

    摘要翻译: 提供了系统和方法,用于在进行多次测量时优化质谱仪系统的性能。 例如,质谱仪(如串联质谱仪)的不同组分或阶段的总沉降时间通过最佳排序测量来降低。

    Concave electrode ion pipe
    5.
    发明授权

    公开(公告)号:US06646258B2

    公开(公告)日:2003-11-11

    申请号:US09766701

    申请日:2001-01-22

    IPC分类号: B01D5944

    CPC分类号: H01J49/42

    摘要: An apparatus for delivering ions between vacuum stages. The apparatus includes a concave electrode ion pipe originating in a first vacuum stage and terminating in a second vacuum stage. The design of the concave electrode ion pipe provides for transport of ions over long distances without substantial loss of the ions while at the same time restricting overall gas flow. The invention allows for the elimination of vacuum stages or a reduction in vacuum pumping speed(s) if the same number of vacuum stages is employed.

    SYSTEMS AND METHODS FOR DECREASING SETTLING TIMES IN MS/MS
    6.
    发明申请
    SYSTEMS AND METHODS FOR DECREASING SETTLING TIMES IN MS/MS 有权
    用于减少MS / MS中的沉降时间的系统和方法

    公开(公告)号:US20100051798A1

    公开(公告)日:2010-03-04

    申请号:US12617028

    申请日:2009-11-12

    IPC分类号: B01D59/44 H01J49/00

    CPC分类号: H01J49/0027 H01J49/004

    摘要: Systems and methods are provided for optimizing the performance of a mass spectrometer system when multiple measurements are made. For example, the total settling time of different components or stages of a mass spectrometer, such as a tandem mass spectrometer, are decreased by optimally ordering the measurements.

    摘要翻译: 提供了系统和方法,用于在进行多次测量时优化质谱仪系统的性能。 例如,质谱仪(如串联质谱仪)的不同组分或阶段的总沉降时间通过最佳排序测量来降低。

    Systems and methods for decreasing settling times in MS/MS
    7.
    发明授权
    Systems and methods for decreasing settling times in MS/MS 有权
    减少MS / MS沉降时间的系统和方法

    公开(公告)号:US07638762B2

    公开(公告)日:2009-12-29

    申请号:US11537355

    申请日:2006-09-29

    IPC分类号: H01J49/40

    CPC分类号: H01J49/0027 H01J49/004

    摘要: Systems and methods are provided for optimizing the performance of a mass spectrometer system when multiple measurements are made. For example, the total settling time of different components or stages of a mass spectrometer, such as a tandem mass spectrometer, are decreased by optimally ordering the measurements.

    摘要翻译: 提供了系统和方法,用于在进行多次测量时优化质谱仪系统的性能。 例如,质谱仪(如串联质谱仪)的不同组分或阶段的总沉降时间通过最佳排序测量来降低。