利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

23 条记录 (耗时 0.036 秒)

    Ice-mediated introduction of substances into biological material
    1.
    发明授权
    Ice-mediated introduction of substances into biological material 失效
    冰介导物质引入生物材料

    公开(公告)号：US5219746A

    公开(公告)日：1993-06-15

    申请号：US863356

    申请日：1992-03-31

    申请人： Chris Brinegar ,  James Gilmore ,  Michael Johnson ,  Nigel Walker

    发明人： Chris Brinegar ,  James Gilmore ,  Michael Johnson ,  Nigel Walker

    IPC分类号： A61K47/48 ,  C12M3/00 ,  C12N15/82 ,  C12N15/87

    CPC分类号： C12N15/87 ,  A61K47/48861 ,  C12M35/08 ,  C12N15/8207

    摘要： Methods and apparatus for the introduction of foreign substances, such as recombinant DNA, into living cell interiors is disclosed. The desired substance to be introduced is dissolved or suspended in water or another suitable liquid to form a solution which is then nebulized and frozen to produce ice particles. These ice particles are accelerated toward and impact upon a target tissue where some of the particles impregnate at least some cells in the target tissue without killing the cells. Following impregnation, the ice particles melt, leaving behind the desired substance in the protoplasm of the bombarded cell.

    摘要翻译： 公开了将诸如重组DNA等异物引入活细胞内部的方法和装置。 要引入的所需物质溶解或悬浮在水或其他合适的液体中以形成溶液，然后将其雾化并冷冻以产生冰颗粒。 这些冰颗粒被加速并冲击到靶组织上，其中一些颗粒浸渍靶组织中的至少一些细胞而不会杀死细胞。 在浸渍之后，冰颗粒熔化，在被轰击的细胞的原生质体中留下所需物质。

    Fusing system including a backup belt assembly
    2.
    发明申请
    Fusing system including a backup belt assembly 有权
    定影系统包括备用皮带组件

    公开(公告)号：US20070071518A1

    公开(公告)日：2007-03-29

    申请号：US11234362

    申请日：2005-09-23

    申请人： Bryan Blair ,  James Gilmore ,  Miranda Oaks

    发明人： Bryan Blair ,  James Gilmore ,  Miranda Oaks

    IPC分类号： G03G15/20

    CPC分类号： G03G15/206 ,  G03G2215/2009 ,  G03G2215/2064

    摘要： In accordance with a first aspect of the present invention, a system is provided for fusing an unfixed toner image to a substrate comprising a rotatable hot fusing roll and a backup belt assembly. The belt assembly may comprise a backup belt and a housing structure including a nip forming pressure roll. The backup belt may be wrapped about the housing structure including the nip forming pressure roll. Preferably, the pressure roll applies a force to the belt so as to form the sole nip region between the rotatable fusing roll and the backup belt.

    摘要翻译： 根据本发明的第一方面，提供了一种用于将未定影的调色剂图像熔合到包括可旋转热定影辊和支撑带组件的基底的系统。 带组件可以包括支撑带和包括辊隙成形压力辊的壳体结构。 支撑带可以围绕包括辊隙成形压力辊的壳体结构缠绕。 优选地，压力辊对带施加力，以便在可旋转定影辊和备用带之间形成唯一的夹持区域。

    METHODS AND SYSTEMS FOR IN SILICO EXPERIMENTAL DESIGN AND FOR PROVIDING A BIOTECHNOLOGY PRODUCT TO A CUSTOMER
    4.
    发明申请
    METHODS AND SYSTEMS FOR IN SILICO EXPERIMENTAL DESIGN AND FOR PROVIDING A BIOTECHNOLOGY PRODUCT TO A CUSTOMER 审中-公开
    用于硅胶实验设计和向客户提供生物技术产品的方法和系统

    公开(公告)号：US20120221432A1

    公开(公告)日：2012-08-30

    申请号：US12791820

    申请日：2010-06-01

    申请人： Shao-Min Yuan ,  Michael Beltsov ,  Thomas G. Chappell ,  Kevin Clancy ,  Peter McGarvey ,  Sam Zaremba ,  James Caffrey ,  Konstantin Belov ,  Anatoliy Mnev ,  Siamak BAHARLOO ,  Aruna Myneni ,  James Gilmore

    发明人： Shao-Min Yuan ,  Michael Beltsov ,  Thomas G. Chappell ,  Kevin Clancy ,  Peter McGarvey ,  Sam Zaremba ,  James Caffrey ,  Konstantin Belov ,  Anatoliy Mnev ,  Siamak BAHARLOO ,  Aruna Myneni ,  James Gilmore

    IPC分类号： G06Q30/06

    CPC分类号： G06Q30/0623 ,  G06Q50/22 ,  G06Q99/00 ,  G16B50/00 ,  Y02A90/22 ,  Y02A90/24

    摘要： Provided herein is a method and computer program product for designing and/or simulating a biotechnology experiment in silico; and for providing and generating revenue from a customized list of one or more biotechnology products and/or services related to the in silico designed or simulated biotechnology experiment or the product of that experiment. In illustrative examples, the products and or services are indirectly related to a biomolecule designed by the in silico designed biotechnology experiment. In addition, provided herein is a method and computer system for generating revenue, that includes providing a customer with a first computer program product for designing or performing a biotechnology experiment in silico; and providing the customer with access to a purchase function for purchasing a second computer program product for designing or performing a biotechnology experiment in silico. Typically, functionality of the first computer product is less then and/or different than the functionality of the second computer product.

    摘要翻译： 本文提供了一种用于在计算机上设计和/或模拟生物技术实验的方法和计算机程序产品; 以及通过与计算机设计或模拟生物技术实验或该实验的产品相关的一个或多个生物技术产品和/或服务的定制列表来提供和产生收入。 在说明性实例中，产品和/或服务与通过计算机设计的生物技术实验设计的生物分子间接相关。 此外，本文提供了一种用于产生收入的方法和计算机系统，其包括为客户提供用于以计算机设计或执行生物技术实验的第一计算机程序产品; 并为客户提供访问购买功能以购买用于以计算机设计或执行生物技术实验的第二计算机程序产品。 通常，第一计算机产品的功能小于和/或不同于第二计算机产品的功能。

    Fuser having reduced axial temperature droop
    6.
    发明申请
    Fuser having reduced axial temperature droop 有权
    定影器具有降低的轴向温度下垂

    公开(公告)号：US20060275061A1

    公开(公告)日：2006-12-07

    申请号：US11142997

    申请日：2005-06-02

    申请人： Jichang Cao ,  James Gilmore

    发明人： Jichang Cao ,  James Gilmore

    IPC分类号： G03G15/20

    CPC分类号： G03G15/2017

    摘要： An apparatus is provided for fixing toner to a substrate including a heated fusing roller having a fusing surface. A heater element is located inside the fusing roller. A nip forming member cooperates with the fusing roller to define a fusing nip. A passive temperature control structure including a pair of members is located adjacent opposing end sections of the fusing roller, the passive temperature control structure operating to retain heat in the end sections. The passive temperature control structure may include heat reflecting members located adjacent to peripheral end portions of the hot roller to reflect heat back to the peripheral surface. In addition, the passive temperature control structure may include an end reflector facing axially toward an interior area or the hot roller for reflecting heat back to the interior of the hot roller. The temperature control structure may also comprise a heat dissipating structure including a heat absorbing roller engaged with the fusing roller or ventilation windows formed in a cover over the fusing roller.

    摘要翻译： 提供了一种用于将调色剂固定到包括具有熔化表面的加热定影辊的基底的装置。 加热元件位于定影辊内部。 夹持形成构件与定影辊配合以限定定影辊隙。 包括一对构件的被动温度控制结构位于定影辊的相对端部附近，该被动温度控制结构用于在端部部分中保持热量。 被动温度控制结构可以包括邻近热辊的外周端部定位的反射构件，以将热量反射回到外围表面。 此外，被动温度控制结构可以包括朝向内部区域轴向的端部反射器或用于将热量反射回热辊内部的热辊。 温度控制结构还可以包括散热结构，其包括与定影辊接合的吸热辊或形成在定影辊上的盖中的通风窗口。

    Backup belt assembly for use in a fusing system and fusing systems therewith
    8.
    发明申请
    Backup belt assembly for use in a fusing system and fusing systems therewith 有权
    用于熔接系统的备用带组件和与其融合的系统

    公开(公告)号：US20050163542A1

    公开(公告)日：2005-07-28

    申请号：US10766767

    申请日：2004-01-28

    申请人： James Gilmore ,  John Kietzman ,  Michael Maul

    发明人： James Gilmore ,  John Kietzman ,  Michael Maul

    IPC分类号： G03G15/20

    CPC分类号： G03G15/2057 ,  G03G15/2064 ,  G03G2215/2009

    摘要： Fusing systems are provided that utilize a heated fusing roller in conjunction with a backup belt assembly to provide a large fusing region within a minimal amount of space. The heated fusing roller comprises a thin walled steel roll having an elastomeric inner layer and a non-resilient flouropolymer release layer. The thin wall steel core allows for relatively faster warm up times compared to conventional fusing systems. Moreover, the backup belt assembly allows for the varying of the pressure profile and the enhancement of media release. The utilization of this design minimizes the size of the system necessary to attain the adhesion of toner to the media, which in turn reduces the cost of the mechanism. Further, the use of the varying pressure nip minimizes the amount of friction between a belt support member and the belt itself, which may reduce friction, wear, and will reduce the risk of print quality defects. Overall, the various embodiments of the present invention contain functional flexibility, a relatively small functional envelope, and better performance at a lower cost compared to conventional fusing systems.

    摘要翻译： 提供熔接系统，其利用加热的定影辊与备用带组件结合，以在最小量的空间内提供大的熔化区域。 加热的定影辊包括具有弹性体内层和非弹性荧光聚合物释放层的薄壁钢辊。 与传统的定影系统相比，薄壁钢芯可以实现相对较快的预热时间。 此外，备用带组件允许改变压力分布和增强介质释放。 利用这种设计使得调色剂粘附到介质所必需的系统的尺寸最小化，这又降低了机构的成本。 此外，使用变化的压力压区使得带支撑构件和带本身之间的摩擦量最小化，这可以减少摩擦，磨损，并且将降低打印质量缺陷的风险。 总体而言，与传统的定影系统相比，本发明的各种实施例包含功能灵活性，相对小的功能包络和更好的性能。

    BIOLOGICAL CONFIRMATION AND DETECTION SYSTEM
    10.
    发明申请
    BIOLOGICAL CONFIRMATION AND DETECTION SYSTEM 审中-公开
    生物确认与检测系统

    公开(公告)号：US20100015601A1

    公开(公告)日：2010-01-21

    申请号：US11719703

    申请日：2005-11-23

    申请人： James Gilmore ,  James Meegan

    发明人： James Gilmore ,  James Meegan

    IPC分类号： C12Q1/68 ,  C12M1/00 ,  C40B60/12 ,  C40B30/00

    CPC分类号： G01N1/2202 ,  G01N1/2211 ,  G01N1/40 ,  G01N2015/0088

    摘要： The present disclosure describes a method and apparatus for collecting samples of particles from air or other gases at one or more monitored locations, and identifying in real-time whether biological agents, such as bacterial or viral pathogens, are present in the samples. The apparatus preferably uses a liquid-assisted collector to collect the sample of particles, which are suspended in a liquid that contains dyes that detect the presence of nucleic acids. An integrated detector with a light source and a light detector detects whether there is a change in the fluorescence of the liquid, which indicates the presence of a biological agent in the sample.

    摘要翻译： 本公开描述了一种用于从一个或多个监测位置处的空气或其它气体中收集颗粒样品的方法和装置，并且实时鉴定样品中是否存在生物试剂（例如细菌或病毒病原体）。 该装置优选使用液体辅助收集器来收集悬浮在包含检测核酸存在的染料的液体中的颗粒样品。 具有光源和光检测器的集成检测器检测液体的荧光是否发生变化，这表明样品中存在生物试剂。