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    Bacteria with reduced genome
    5.
    发明申请
    Bacteria with reduced genome 有权
    具有降低的基因组的细菌

    公开(公告)号：US20070031969A1

    公开(公告)日：2007-02-08

    申请号：US11173900

    申请日：2005-07-01

    申请人： Frederick Blattner ,  Gyorgy Posfai ,  Christopher Herring ,  Guy Plunkett ,  Jeremy Glasner

    发明人： Frederick Blattner ,  Gyorgy Posfai ,  Christopher Herring ,  Guy Plunkett ,  Jeremy Glasner

    IPC分类号： C12N15/74 ,  C12N1/21

    CPC分类号： C12N15/102 ,  C12N1/08 ,  C12R1/19

    摘要： The present invention provides a bacterium having a genome that is genetically engineered to be at least 2 to 14% smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present invention also provides methods for deleting genes and other DNA sequences from a bacterial genome. The methods provide precise deletions and seldom introduces mutations to the genomic DNA sequences around the deletion sites. Thus, the methods can be used to generate a series of deletions in a bacterium without increasing the possibility of undesired homologous recombination within the genome. In addition, some of the methods provided by the present invention can also be used for replacing a region of a bacterial genome with a desired DNA sequence.

    摘要翻译： 本发明提供了一种具有遗传工程化至少比其天然亲本菌株的基因组小至少2至14％的基因组的细菌。 具有较小基因组的细菌可以更有效地产生商业产品。 本发明还提供从细菌基因组中删除基因和其他DNA序列的方法。 该方法提供精确的缺失，很少引入缺失位点周围基因组DNA序列的突变。 因此，该方法可用于在细菌中产生一系列缺失，而不增加基因组内不希望的同源重组的可能性。 此外，本发明提供的一些方法也可用于用期望的DNA序列替代细菌基因组的区域。

    SYSTEM AND METHOD FOR CONCURRENT WIRELESS VOICE AND DATA COMMUNICATIONS
    8.
    发明申请
    SYSTEM AND METHOD FOR CONCURRENT WIRELESS VOICE AND DATA COMMUNICATIONS 有权
    用于同时无线语音和数据通信的系统和方法

    公开(公告)号：US20070104259A1

    公开(公告)日：2007-05-10

    申请号：US11620535

    申请日：2007-01-05

    申请人： Christopher Herring ,  Dannie Feekes

    发明人： Christopher Herring ,  Dannie Feekes

    IPC分类号： H04L5/16

    CPC分类号： H04B7/2656

    摘要： Unitary transceiving units employ a multiple carrier, time-division-multiple-access (TDMA), time-division-duplex (TDD protocol to conduct concurrent wireless voice and data communications wherein a first transceiving base station unit tethered to a network interface wirelessly communicates to a second, mobile transceiving unit. The mobile transceiving unit wirelessly transmits and receives packetized voice and data information that is separated and routed to respective voice or data networks. The unitary mobile transceiving unit thus functions as a concurrent voice phone and data communications terminal/computer.

    摘要翻译： 单一收发单元采用多载波，时分多址（TDMA），时分双工（TDD协议，进行并发无线语音和数据通信，其中第一收发基站单元与网络接口无线通信到 第二个移动收发单元，移动收发单元无线地发送和接收分离的语音和数据信息，分离和路由到相应的语音或数据网络，因此单一移动收发单元作为并发语音电话和数据通信终端/计算机 。

    Bacteria with reduced genome
    9.
    发明申请
    Bacteria with reduced genome 审中-公开
    具有降低的基因组的细菌

    公开(公告)号：US20060270043A1

    公开(公告)日：2006-11-30

    申请号：US10896739

    申请日：2004-07-22

    申请人： Frederick Blattner ,  Gyorgy Posfai ,  Christopher Herring ,  Guy Plunkett ,  Jeremy Glasner

    发明人： Frederick Blattner ,  Gyorgy Posfai ,  Christopher Herring ,  Guy Plunkett ,  Jeremy Glasner

    IPC分类号： C12N15/74 ,  C12N1/21

    CPC分类号： C12N15/102 ,  C12N15/70

    摘要： The present invention provides a bacterium having a genome that is genetically engineered to be at least 2 to about 20% smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present invention also provides methods for deleting genes and other DNA sequences from a bacterial genome. The methods provide precise deletions and seldom introduces mutations to the genomic DNA sequences around the deletion sites. Thus, the methods can be used to generate a series of deletions in a bacterium without increasing the possibility of undesired homologous recombination within the genome. In addition, some of the methods provided by the present invention can also be used for replacing a region of a bacterial genome with a desired DNA sequence.

    摘要翻译： 本发明提供了具有基因组的细菌，其基因组被改造为比其天然亲本菌株的基因组小至少2至约20％。 具有较小基因组的细菌可以更有效地产生商业产品。 本发明还提供从细菌基因组中删除基因和其他DNA序列的方法。 该方法提供精确的缺失，很少引入缺失位点周围基因组DNA序列的突变。 因此，该方法可用于在细菌中产生一系列缺失，而不增加基因组内不希望的同源重组的可能性。 此外，本发明提供的一些方法也可用于用期望的DNA序列替代细菌基因组的区域。