Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
    1.
    发明申请
    Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors 失效
    使用8-氨基 - 芳基取代的咪唑并吡嗪作为激酶抑制剂

    公开(公告)号:US20050009832A1

    公开(公告)日:2005-01-13

    申请号:US10845586

    申请日:2004-05-14

    IPC分类号: C07D487/04 A61K31/498

    CPC分类号: C07D487/04

    摘要: The present invention relates to 8-amino-aryl-substituted imidazopyrazines which modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

    摘要翻译: 本发明涉及调节蛋白激酶(“PK”)活性的8-氨基 - 芳基取代的咪唑并吡嗪。 因此,本发明的化合物可用于治疗与异常PK活性相关的疾病。 还公开了包含这些化合物的药物组合物,利用包含这些化合物的药物组合物治疗疾病的方法及其制备方法。

    Process for the recovery of titanium in mixed chloride media
    2.
    发明申请
    Process for the recovery of titanium in mixed chloride media 有权
    在混合氯化物介质中回收钛的方法

    公开(公告)号:US20050142051A1

    公开(公告)日:2005-06-30

    申请号:US10981143

    申请日:2004-11-04

    摘要: A process for leaching a value metal from a titanium-bearing ore material comprising the step of leaching the ore material at atmospheric pressure with a lixiviant comprising a chloride and hydrochloric acid is disclosed. The leaching conditions are such that titanium is leached and remains in solution. The temperature is maintained at less that 85° C., and the concentration of hydrochloric acid is preferably less than 20% (mass ratio). The preferred chloride is magnesium chloride. The lixiviant may contain oxidant e.g. sodium chlorate or chlorine.

    摘要翻译: 公开了一种用于从含钛矿石材料中浸出含金属的方法,包括在大气压下用含氯化物和盐酸的浸液浸出矿石材料的步骤。 浸出条件是使钛浸​​出并保留在溶液中。 温度保持在85℃以下,盐酸浓度优选小于20%(质量比)。 优选的氯化物是氯化镁。 浸渍剂可含有氧化剂 氯酸钠或氯气。

    Resilient deck board fastener
    5.
    发明申请
    Resilient deck board fastener 有权
    弹性甲板板紧固件

    公开(公告)号:US20050063771A1

    公开(公告)日:2005-03-24

    申请号:US10668879

    申请日:2003-09-23

    申请人: G. Harris

    发明人: G. Harris

    IPC分类号: E04F15/04 F16B5/00 F16B7/00

    摘要: A fastener for securing deck boards to a support structure without the need for driving screws or nails through the deck boards. The fastener includes two horizontal flanges that fit into slots cut into the sides of adjacent deck boards, a center hole for securing the fastener to the support structure and deformable, resilient elements that bridge the gap between adjacent deck boards during fastening yet compress inward when the boards swell and expand.

    摘要翻译: 用于将甲板板固定到支撑结构上的紧固件,而不需要通过甲板板驱动螺钉或钉子。 紧固件包括两个水平凸缘,其配合到切割到相邻甲板板的侧面的槽中,用于将紧固件固定到支撑结构的中心孔和可变形的弹性元件,其在紧固期间桥接相邻甲板板之间的间隙, 板膨胀膨胀。