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公开(公告)号：US11305063B2
公开(公告)日：2022-04-19
申请号：US16482363
申请日：2018-01-22
申请人： Consort Medical PLC
摘要： A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented. In the second syringe position venting of the propellant from the second chamber through the second fluid pathway is permitted to enable a second reduction in the vapour pressure in the second chamber.
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公开(公告)号：US10905829B2
公开(公告)日：2021-02-02
申请号：US15032912
申请日：2014-11-03
申请人： CONSORT MEDICAL PLC
发明人： Alastair Willoughby , Marta Vilaplana , Alan Judd
摘要： A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.
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公开(公告)号：US09527657B2
公开(公告)日：2016-12-27
申请号：US14406083
申请日：2013-06-07
申请人： Consort Medical PLC
IPC分类号： B65D83/00 , B65D83/24 , B65B51/26 , B65B51/30 , B65B31/04 , A61M5/20 , A61M5/155 , A61M39/22 , A61M5/168 , A61M5/44 , B65D83/48 , A61M5/142 , A61M5/145
CPC分类号： B65D83/24 , A61M5/142 , A61M5/14526 , A61M5/155 , A61M5/16804 , A61M5/16881 , A61M5/2053 , A61M5/44 , A61M39/22 , A61M2005/14513 , A61M2039/2486 , A61M2207/00 , A61M2207/10 , B65B31/045 , B65B51/26 , B65B51/30 , B65D83/48 , F04C2270/0421 , Y10T29/49 , Y10T29/49808
摘要： A valve for discharging a fluid, comprising: a valve body at least partially defining a fluid chamber; and a valve stem extending into the fluid chamber, the valve stem comprising an outlet port for transfer, in use, of fluid from the fluid chamber into the valve stem; the valve stem being slidably movable relative to the valve body from: i) a non-dispensing position in which the outlet port is out of communication with the fluid chamber; to ii) a dispensing position in which the outlet port is in fluid communication with the fluid chamber so as to permit transfer of the fluid from the fluid chamber into the valve stem; wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.
摘要翻译： 一种用于排出流体的阀，包括：至少部分地限定流体室的阀体; 以及阀杆，其延伸到所述流体室中，所述阀杆包括用于在使用中将流体从所述流体室传送到所述阀杆中的出口端口; 所述阀杆可相对于所述阀体可滑动地移动，其特征在于：i）所述出口与所述流体室不连通的非分配位置; ii）分配位置，其中所述出口与所述流体室流体连通，以便允许所述流体从所述流体室传递到所述阀杆中; 其中所述阀还包括锁定构件，所述锁定构件被构造成一旦所述阀杆滑动超过锁定位置，则防止所述阀杆返回到所述非分配位置。
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公开(公告)号：US10751483B2
公开(公告)日：2020-08-25
申请号：US15567901
申请日：2016-04-21
申请人： Consort Medical PLC
发明人： Steven Hatch , Alastair Willoughby , Guy Moseley , Dan Garson
摘要： A medicament delivery device has a syringe, a housing, a needle shield, a biasing member and one or more blocking members. The needle shield is biased axially forwardly by the biasing member so as to selectively cover a needle of the syringe. However, the biasing member is prevented from biasing the needle shield axially forwardly until a radial movement of the blocking members has occurred, which is precipitated by a forward axial movement of the syringe. Consequently, the forward movement of the syringe releases the needle shield to automatically make safe the device.
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公开(公告)号：US20150183571A1
公开(公告)日：2015-07-02
申请号：US14406083
申请日：2013-06-07
申请人： Consort Medical PLC
CPC分类号： B65D83/24 , A61M5/142 , A61M5/14526 , A61M5/155 , A61M5/16804 , A61M5/16881 , A61M5/2053 , A61M5/44 , A61M39/22 , A61M2005/14513 , A61M2039/2486 , A61M2207/00 , A61M2207/10 , B65B31/045 , B65B51/26 , B65B51/30 , B65D83/48 , F04C2270/0421 , Y10T29/49 , Y10T29/49808
摘要： A valve for discharging a fluid, comprising: a valve body at least partially defining a fluid chamber; and a valve stem extending into the fluid chamber, the valve stem comprising an outlet port for transfer, in use, of fluid from the fluid chamber into the valve stem; the valve stem being slidably movable relative to the valve body from: i) a non-dispensing position in which the outlet port is out of communication with the fluid chamber; to ii) a dispensing position in which the outlet port is in fluid communication with the fluid chamber so as to permit transfer of the fluid from the fluid chamber into the valve stem; wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.
摘要翻译： 一种用于排出流体的阀，包括：至少部分地限定流体室的阀体; 以及阀杆，其延伸到所述流体室中，所述阀杆包括用于在使用中将流体从所述流体室传送到所述阀杆中的出口端口; 所述阀杆可相对于所述阀体可滑动地移动，其特征在于：i）所述出口与所述流体室不连通的非分配位置; ii）分配位置，其中所述出口与所述流体室流体连通，以便允许所述流体从所述流体室传送到所述阀杆中; 其中所述阀还包括锁定构件，所述锁定构件被构造成一旦所述阀杆滑动超过锁定位置，则防止所述阀杆返回到所述非分配位置。
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公开(公告)号：US20160279323A1
公开(公告)日：2016-09-29
申请号：US15032554
申请日：2014-10-27
申请人： CONSORT MEDICAL PLC
IPC分类号： A61M5/145
CPC分类号： A61M5/14526 , A61M5/1454 , A61M5/16877 , A61M5/31515 , A61M2005/14513 , A61M2005/2086 , A61M2205/3334 , A61M2206/22
摘要： A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber. The first stopper is connected to the second stopper by a tensile member such that axially forwardly movement of the first stopper causes axially forwardly movement of the second stopper due to tensioning of the tensile member. The first stopper is driveable in an axially forwardly direction, the first chamber is configured to contain medicament for delivery through the delivery outlet as the first stopper moves axially forwards, the third chamber contains a viscous fluid that enters the venting chamber via the vent outlet as the second stopper moves axially forwards, and the fourth chamber has a pressure that is substantially equal to or greater than the pressure of the venting chamber. As the first stopper is driven axially forwardly, the tensile member is tensioned and causes the second stopper to move axially forwardly and the venting of viscous fluid into the venting chamber via the vent outlet retards the axially forward movement of the second stopper and the first stopper.
摘要翻译： 一种药物输送装置，包括在其前端具有输送出口的第一容器和在第一容器中可轴向移动的第一止动件，第一止动件限定和分离第一容器中的第一腔室和第二腔室，其中第一腔室 位于第一止动件的轴向前方，第二腔室位于第一止动件的轴向后方。 所述药物输送装置还包括具有可在所述第二容器中轴向移动的第二止动件的第二容器，所述第二止动件限定并分离所述第二容器中的第三室和第四室，其中所述第三室沿所述第二容器的轴向向前延伸， 所述第四腔室位于所述第二塞子的轴向后方，并且所述第三腔室具有与排气室流体连通的通气口。 第一止动件通过拉伸构件连接到第二止动件，使得第一止动件的轴向向前运动由于拉伸构件的张紧而引起第二塞子的轴向向前运动。 第一止动件可在轴向向前方向上驱动，第一腔被配置为当第一止动件轴向向前移动时容纳用于通过输送出口输送的药物，第三腔室包含通过排气口进入通气室的粘性流体， 第二止动件轴向向前移动，并且第四室具有基本上等于或大于排气室的压力的压力。 当第一止动件被轴向向前驱动时，拉伸构件被张紧并且使得第二止动件轴向向前移动，并且粘性流体经由排气口排出到通气室中延迟第二止动件和第一止动件的轴向向前运动 。
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公开(公告)号：US20160263323A1
公开(公告)日：2016-09-15
申请号：US15033133
申请日：2014-11-03
申请人： CONSORT MEDICAL PLC
发明人： Rachel Koppelman , Alan Judd , Alastair Willoughby
CPC分类号： A61M5/20 , A61M5/2053 , A61M5/3148 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M5/46 , A61M2005/2026 , A61M2005/3247 , A61M2005/3267
摘要： A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.
摘要翻译： 一种用于药物输送装置的子组件，包括壳体，包含在所述壳体中并可轴向移动的推进剂源，以及相对于所述壳体可轴向移动的按钮。 所述按钮的至少一部分设置在所述推进剂源的一部分的轴向后方。 按钮包括一个或多个径向柔性的阻挡构件，并且按钮可在第一轴向位置之间移动，在该第一轴向位置中，一个或多个径向柔性阻挡构件在径向向内的位置中被壳体径向地约束，从而限制推进剂的向后轴向运动 源和第二轴向位置，其中一个或多个径向柔性阻挡构件能够弯曲到径向向外的位置，并且允许推进剂源相对于按钮和壳体的向后轴向移动。
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公开(公告)号：US10792428B2
公开(公告)日：2020-10-06
申请号：US15567882
申请日：2016-04-21
申请人： Consort Medical PLC
摘要： A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe. Propellant introduced into the expandable housing may pass through the narrow channel into the second chamber and cause forward axial movement of the stopper in the barrel to expel medicament contained in the first chamber through the open end, where axial movement of the stopper in the barrel commences after axial movement of the syringe.
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公开(公告)号：US10653831B2
公开(公告)日：2020-05-19
申请号：US15032554
申请日：2014-10-27
申请人： CONSORT MEDICAL PLC
摘要： A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.
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公开(公告)号：US10556068B2
公开(公告)日：2020-02-11
申请号：US15759642
申请日：2016-08-19
申请人： CONSORT MEDICAL PLC
发明人： Robert Glover , Alastair Willoughby , Brad Howarth
摘要： An injection device having an outer housing configured to receive a syringe. The syringe has a barrel for containing medicament and a needle in fluid communication with the barrel. The device further has a needle shield axially moveable relative to the outer housing between a needle covering position and a needle exposing position and a helical compression spring to bias the needle shield axially forwardly toward the needle covering position. A locking sleeve, axially movable relative to the outer housing between a non-locking position and a locking position, selectively limits axial movement of the needle shield. In a first configuration, the needle shield is axially slideable within the locking sleeve to permit rearward axial movement of the needle shield from the needle covering position to the needle exposing position.
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