公开(公告)号：US11550166B2

公开(公告)日：2023-01-10

申请号：US16884077

申请日：2020-05-27

Applicant: CooperVision International Limited

Inventor： Sourav Saha ,  Victoria Rogers ,  Charles B. Derringer ,  Sarah Tao ,  Szeshen Chuah ,  Yuan Sun ,  Yuwen Liu ,  Nancy Keir ,  Tim Warren ,  Matthew S. Linn ,  Lu Jiang

IPC: G02C7/04 ,  G02B1/04

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

公开(公告)号：US20230331935A1

公开(公告)日：2023-10-19

申请号：US18042598

申请日：2021-09-16

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  COOPERVISION INTERNATIONAL LIMITED

Inventor： Alireza Khademhosseini ,  Shiming Zhang ,  Sourav Saha ,  Mehmet R. Dokmeci ,  Lu Jiang

IPC: C08J3/075 ,  A61B5/1477 ,  A61B5/145 ,  A61F9/00 ,  G02B1/04 ,  G02C7/04 ,  B29D11/00

CPC classification number: C08J3/075 ,  A61B5/1477 ,  A61B5/14507 ,  A61B5/14546 ,  A61F9/0017 ,  G02B1/043 ,  G02C7/049 ,  B29D11/00048 ,  B29D11/00096 ,  C08J2333/10 ,  C08J2481/08 ,  B29K2105/0061

Abstract: Microchannels in hydrogels play an essential role in enabling a smart contact lens. A wearable contact lens is disclosed herein that uses microchannels and connected chambers located in poly-2-hydroxyethyl methacrylate (poly(HEMA)) hydrogel that is used in a commercial contact lens with three-dimensional (3D) printed mold. The corresponding capillary flow behaviors in these microchannels were investigated. Different capillary flow regimes were observed in these microchannels, depending on the hydration level of the hydrogel material. In particular, it was found that a peristaltic pressure could reinstate flow in a dehydrated microchannel, indicating the motion of eye-blinking may help tear flow in a microchannel-containing contact lens. Colorimetric pH and electrochemical Na+ sensing capabilities were demonstrated in these microchannels. Micro-engineered contact lenses formed using poly(HEMA) hydrogel can be used for various biomedical applications such as eye-care and wearable biosensing.

公开(公告)号：US11782297B2

公开(公告)日：2023-10-10

申请号：US17389715

申请日：2021-07-30

Applicant: CooperVision International Limited

Inventor： Matthew S. Linn ,  Sourav Saha ,  Lu Jiang ,  Tim Warren ,  Nancy J. Keir

IPC: G02C7/04 ,  B29D11/00

CPC classification number: G02C7/049 ,  G02C7/047 ,  B29D11/00067 ,  B29D11/00134

Abstract: A contact lens having dimples on a posterior surface is described as well as cast molds and injection molding inserts for manufacturing the same. The contact lens includes a posterior surface having an optic zone, a peripheral zone, and a circumferential edge, where dimples are located in the peripheral zone, and can include at least 1000 dimples.

公开(公告)号：US11947192B2

公开(公告)日：2024-04-02

申请号：US18075444

申请日：2022-12-06

Applicant: CooperVision International Limited

Inventor： Sourav Saha ,  Victoria Rogers ,  Charles B. Derringer ,  Sarah Tao ,  Szeshen Chuah ,  Yuan Sun ,  Yuwen Liu ,  Nancy Keir ,  Tim Warren ,  Matthew S. Linn ,  Lu Jiang

IPC: G02C7/04 ,  G02B1/04

CPC classification number: G02C7/04 ,  G02B1/043

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.