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公开(公告)号：US20240156639A1
公开(公告)日：2024-05-16
申请号：US18508806
申请日：2023-11-14
CPC分类号： A61F9/0017 , B29D11/00038 , B29D11/00096 , G02C7/049 , B29K2105/0061
摘要： A contact lens may include a lens comprising a hydrogel configured to be worn on an eyeball. A contact lens may include an electronic component fully encapsuled within the lens, wherein the electronic component may include a sensor, a battery, a supercapacitor, an electronically controlled microfluidic channel, or combinations thereof. Methods for producing such a contact lens are also disclosed.
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2.发明公开公开(公告)号：US20230371814A1
公开(公告)日：2023-11-23
申请号：US18197795
申请日：2023-05-16
发明人： Sei Kwang HAHN , Tae Yeon KIM
CPC分类号： A61B3/16 , A61B3/107 , A61F9/0017 , G02C7/04 , B29D11/00096 , A61B2562/0285 , A61B2017/00022
摘要： The present invention relates to a wireless theranostic contact lens, which includes gold hollow nanowires having excellent safety and stability in vivo and excellent sensitivity and a controlled drug delivery system allowed to contain a high content of a drug for treating glaucoma.
The contact lens of the present invention is allowed to monitor intraocular pressure in real time and release an appropriate drug from the controlled drug delivery system according to a state of the intraocular pressure, thereby enabling personalized intraocular pressure adjustment.-
公开(公告)号：US20190232584A1
公开(公告)日：2019-08-01
申请号：US15761761
申请日：2016-09-23
发明人： Jung Wook KIM , Hyun Cheol KIM
CPC分类号： B29D11/00096 , A61K9/0051 , A61K9/1617 , A61K9/1658 , A61K47/36 , B29D11/00 , B29D11/00134 , B29K2089/00 , B29K2995/006 , G02C7/04
摘要： The present invention relates to a method of manufacturing a sustained drug-release contact lens. More specifically, the present invention relates to a method of manufacturing a sustained drug-release contact lens, the method including: forming a body in which the body provides an outer shape of the lens and has a plurality of cavities configured to be recessed and spaced apart from each other by a predetermined distance along a side surface of the contact lens; and filling a drug and forming a closing part in which the cavities of the body formed at the forming the body are filled with the drug and respective closing parts closing the cavities are formed, wherein the closing part is made of a biodegradable material and each closing part is configured to open at a different time during wearing of the contact lens at the forming the body.
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4.发明申请公开(公告)号：US20150044446A1
公开(公告)日：2015-02-12
申请号：US14483637
申请日：2014-09-11
发明人： Morgana M. Trexler , Jenna L. Graham , Jennifer L. Breidenich , Jeffrey P. Maranchi , Julia B. Patrone , Marcia W. Patchan , Jennifer H. Elisseeff , Xiomara Calderon-Colon
CPC分类号： C08J3/075 , A61F2/145 , B29D11/00096 , C08B1/003 , C08J2301/02 , C08L1/02 , C08L33/066 , C08L33/20 , C08L33/26 , C08L2205/02 , C08L2205/16 , G02B1/043 , G02C7/049 , C08L101/14 , C08L33/10 , C08L71/02 , C08L29/04 , C08L39/06 , C08L83/04 , C08L1/08
摘要： The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high oxygen permeability, high biocompatibility, high tensile strength and desirable thermal stability. The present invention further provides a process for preparing a cellulose hydrogel comprising (i) a step of activating cellulose, in which the activating step comprises contacting the cellulose with a solvent to activate the cellulose for a time duration from about 2 hours to about 30 hours; (ii) substantially dissolving the activated cellulose to form a solution; and (iii) gelling the solution to form a gel, in which the gelling step comprises allowing the solution to gel in an environment comprising a relative humidity from about 30% to about 80% at 35° C.
摘要翻译： 本发明提供具有以下性质的一种或多种纤维素水凝胶：高水含量，高透明度，高透氧性，高生物相容性，高拉伸强度和期望的热稳定性。 本发明还提供一种制备纤维素水凝胶的方法，其包括（i）活化纤维素的步骤，其中活化步骤包括使纤维素与溶剂接触以使纤维素活化约2小时至约30小时 ; （ii）基本上溶解活化的纤维素以形成溶液; 和（iii）胶凝溶液以形成凝胶，其中胶凝步骤包括使溶液在35℃下在包含约30％至约80％的相对湿度的环境中凝胶化
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公开(公告)号：US20140086963A1
公开(公告)日：2014-03-27
申请号：US14091192
申请日：2013-11-26
IPC分类号： A61K33/00
CPC分类号： A61K9/0014 , A61K9/0048 , A61K33/00 , A61K33/14 , A61K45/06 , B01F3/04531 , B01F3/0807 , B01F3/0853 , B01F7/00816 , B29D11/00038 , B29D11/00096 , A61K2300/00
摘要： Particular embodiments disclosed herein relate to gas-enriched fluids, methods of making the same, systems for making the same and/or methods of treatment utilizing the gas-enriched fluids for wound care related conditions and/or diseases. In certain embodiments, the gas-enriched fluid is oxygen-enriched water. Certain embodiments relate to cosmetic and/or therapeutic fluids and/or methods of treatment utilizing the fluids in order to treat a cosmetic and/or therapeutic symptom of wound care and/or increase proper wound healing.
摘要翻译： 本文公开的具体实施方案涉及富含气体的流体，其制备方法，制备方法，和/或利用富含气体的流体处理伤口护理相关病症和/或疾病的治疗方法。 在某些实施方案中，富含气体的流体是富氧水。 某些实施方案涉及使用流体的化妆品和/或治疗性流体和/或治疗方法，以便治疗伤口护理的化妆品和/或治疗症状和/或增加适当的伤口愈合。
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公开(公告)号：US08597689B2
公开(公告)日：2013-12-03
申请号：US11978137
申请日：2007-10-25
IPC分类号： A01N39/00
CPC分类号： A61K9/0014 , A61K9/0048 , A61K33/00 , A61K33/14 , A61K45/06 , B01F3/04531 , B01F3/0807 , B01F3/0853 , B01F7/00816 , B29D11/00038 , B29D11/00096 , A61K2300/00
摘要： Particular embodiments disclosed herein relate to gas-enriched fluids, methods of making the same, systems for making the same and/or methods of treatment utilizing the gas-enriched fluids for wound care related conditions and/or diseases. In certain embodiments, the gas-enriched fluid is oxygen-enriched water. Certain embodiments relate to cosmetic and/or therapeutic fluids and/or methods of treatment utilizing the fluids in order to treat a cosmetic and/or therapeutic symptom of wound care and/or increase proper wound healing.
摘要翻译： 本文公开的具体实施方案涉及富含气体的流体，其制备方法，制备方法，和/或利用富含气体的流体处理伤口护理相关病症和/或疾病的治疗方法。 在某些实施方案中，富含气体的流体是富氧水。 某些实施方案涉及使用流体的化妆品和/或治疗性流体和/或治疗方法，以便治疗伤口护理的化妆品和/或治疗症状和/或增加适当的伤口愈合。
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公开(公告)号：US20240300198A1
公开(公告)日：2024-09-12
申请号：US18578898
申请日：2022-07-13
发明人： Leonardo PESI
CPC分类号： B29D11/00096 , B29C33/3842 , B29C33/424 , B29D11/00326 , B29D11/00519 , B29D11/00807 , B29K2823/12 , B29L2011/0041 , B29L2031/757
摘要： The invention concerns a method to manufacture a mold (10) for forming contact lenses (100) using the technique of molding with molds of monomeric and/or polymeric material; such molds (10) comprise a male element (11) and a female element (12), which cooperate to define a cavity suitable to accommodate monomeric and/or polymeric material in the liquid state intended to form the lens (100), wherein the method provides to obtain, by means of laser processing, a plurality of grooves (23) in the male element (11) intended to form functional elements in relief (101) of the lenses (100). The invention also concerns a mold (10) for contact lenses (100) made of monomeric and/or polymeric material that can be obtained with the method as above.
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公开(公告)号：US11977280B2
公开(公告)日：2024-05-07
申请号：US17159025
申请日：2021-01-26
发明人： Stephen D. Newman
IPC分类号： G02C7/04 , A61K9/00 , A61K47/34 , B29C41/04 , B29C41/22 , B29D11/00 , B29K83/00 , B29K105/00 , B29L11/00
CPC分类号： G02C7/049 , A61K9/0051 , A61K47/34 , B29C41/045 , B29C41/22 , B29D11/00038 , B29D11/00096 , B29D11/00115 , B29D11/00865 , B29D11/00894 , G02C7/046 , B29K2083/00 , B29K2105/0061 , B29K2105/0094 , B29L2011/0041
摘要： One embodiment of a contact lens includes a lens body configured to fit directly on the surface of the eye and legible characters positioned on the lens body. Another embodiment of a contact lens comprises a lens body including polymeric material and a lens enhancing material (e.g., ink, silicone material, medicament material, and the like) encapsulated in the polymeric material. The lens enhancing material can be in the form of isolated sections distributed in the surrounding polymeric material. Methods of making contact lenses include forming a first lens layer including a first surface, forming a pattern on the first surface, and forming a second lens layer over the pattern.
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公开(公告)号：US20240036354A1
公开(公告)日：2024-02-01
申请号：US18279214
申请日：2022-04-28
CPC分类号： G02C7/049 , B29D11/00096 , C08J3/075 , G02B1/043 , B29D11/00076
摘要： A WS12-releasing contact lens is described as well as method of manufacturing the same. The WS12-releasing contact lens comprises a polymeric lens body and WS12 releasably adhered to the polymeric lens body, and releases from 0.05 μg to 0.5 μg WS12 after 1 hour in a release media or when worn by a human subject. The WS12-releasing contact lens can be comfortably worn by a symptomatic contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer.
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公开(公告)号：US20160116764A1
公开(公告)日：2016-04-28
申请号：US14890086
申请日：2014-05-08
发明人： Stephen D. NEWMAN
CPC分类号： G02C7/049 , A61K9/0051 , A61K47/34 , B29C41/045 , B29C41/22 , B29D11/00038 , B29D11/00096 , B29D11/00115 , B29D11/00865 , B29D11/00894 , B29K2083/00 , B29K2105/0061 , B29K2105/0094 , B29L2011/0041 , G02C7/046
摘要： One embodiment of a contact lens includes a lens body configured to fit directly on the surface of the eye and legible characters positioned on the lens body. Another embodiment of a contact lens comprises a lens body including polymeric material and a lens enhancing material (e.g., ink, silicone material, medicament material, and the like) encapsulated in the polymeric material. The lens enhancing material can be in the form of isolated sections distributed in the surrounding polymeric material. Methods of making contact lenses include forming a first lens layer including a first surface, forming a pattern on the first surface, and forming a second lens layer over the pattern.
摘要翻译： 隐形眼镜的一个实施例包括被配置为直接配合在眼睛表面上的透镜体和位于透镜体上的可读字符。 隐形眼镜的另一实施例包括透镜体，其包括聚合物材料和包封在聚合物材料中的透镜增强材料（例如油墨，硅树脂材料，药物材料等）。 透镜增强材料可以是分布在周围聚合物材料中的隔离部分的形式。 制造隐形眼镜的方法包括形成包括第一表面的第一透镜层，在第一表面上形成图案，以及在图案上形成第二透镜层。
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