公开(公告)号：US20230220429A1

公开(公告)日：2023-07-13

申请号：US17864715

申请日：2022-07-14

申请人： DAESANG CORPORATION

发明人： Hyun Ho KIM ,  Sun Hee LEE ,  Dong Hyun KIM ,  Hyun Sook KIM ,  Seok Hyun PARK ,  Joon Hyun PARK

IPC分类号： C12P13/14 ,  C12P13/08 ,  C12N1/20 ,  A23L27/24 ,  A23L27/22

CPC分类号： C12P13/14 ,  C12P13/08 ,  C12N1/205 ,  A23L27/24 ,  A23L27/22 ,  C12R2001/15

摘要： The present invention relates to a method of producing a flavor by a co-fermentation process using mixed fermentation of two or more different microorganisms producing different products. The method of producing a flavor may produce a natural flavor capable of improving the taste and aroma of food and the overall sensory properties of food through a fermentation broth containing amino acids, nucleic acids and/or organic acids, which is produced by mixed fermentation of different microorganisms producing different products, that is, different kinds of amino acids, nucleic acids and/or organic acids. This flavor may be used in various food fields.

公开(公告)号：US20240150801A1

公开(公告)日：2024-05-09

申请号：US18280846

申请日：2022-01-19

申请人： DAESANG CORPORATION

发明人： Moon Jeong KIM ,  Dong Seok LEE ,  Sun Jun YOON ,  Seok Hyun PARK ,  Joon Hyun PARK

IPC分类号： C12P13/10 ,  C12N9/10

CPC分类号： C12P13/10 ,  C12N9/1029 ,  C12Y203/01008

摘要： The present invention relates to a Corynebacterium glutamicum mutant strain having increased L-citrulline productivity, and a method of producing L-citrulline using the same. The Corynebacterium glutamicum mutant strain is capable of producing L-citrulline in high yield and high concentration while inhibiting the production of by-products, because the activity of the protein that is expressed by the NCgl2657 gene therein has been weakened or inactivated.

公开(公告)号：US20230136217A1

公开(公告)日：2023-05-04

申请号：US17798792

申请日：2020-08-26

申请人： DAESANG CORPORATION

发明人： Young Ju LEE ,  Bong Ki KIM ,  Min Jin CHOI ,  Seok Hyun PARK ,  Jae Chun HAN

IPC分类号： C12N1/20 ,  C12N15/77

摘要： The present invention relates to a Corynebacterium glutamicum mutant strain having increased L-glutamic acid productivity, a method for constructing the same, and a method of producing L-glutamic acid using the same. The Corynebacterium glutamicum mutant strain is a strain into which a mechanosensitive ion channel gene derived from a Corynebacterium sp. strain has been introduced, and thus it can produce L-glutamic acid in an improved yield due to enhancement of glutamic acid release. Therefore, when the mutant strain is used, it is possible to more effectively produce L-glutamic acid.

公开(公告)号：US20230313244A1

公开(公告)日：2023-10-05

申请号：US18024400

申请日：2021-04-20

申请人： DAESANG CORPORATION

发明人： Mi RYU ,  In Pyo HONG ,  Min Jin CHOI ,  Seok Hyun PARK ,  Jae Chun HAN

IPC分类号： C12P13/08 ,  C12N9/10 ,  C12N15/77

CPC分类号： C12P13/08 ,  C12N9/1025 ,  C12Y203/03001 ,  C12N15/77 ,  C12N2800/101

摘要： The present disclosure relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The Corynebacterium glutamicum mutant strain may produce L-lysine in an improved yield by inhibiting the conversion of oxaloacetate to citrate due to decreased or inhibited expression of the gene encoding the citrate synthase.

公开(公告)号：US20230220430A1

公开(公告)日：2023-07-13

申请号：US17916331

申请日：2021-03-24

申请人： DAESANG CORPORATION

发明人： In Pyo HONG ,  Bong Ki KIM ,  Min Jin CHOI ,  Seok Hyun PARK ,  Jae Chun HAN

IPC分类号： C12P13/14 ,  C12N15/52 ,  C12N15/77 ,  C12N9/00 ,  C12N1/20

CPC分类号： C12P13/14 ,  C12N15/52 ,  C12N15/77 ,  C12N9/93 ,  C12N1/20 ,  C12Y603/01002 ,  C12R2001/15

摘要： The present invention relates to a strain which has increased glutamine productivity due to being transformed with a vector containing a nucleotide sequence that encodes a glutamine synthetase consisting of the amino acid sequence of SEQ ID NO: 1.

公开(公告)号：US20240294896A1

公开(公告)日：2024-09-05

申请号：US18700421

申请日：2022-07-29

申请人： DAESANG CORPORATION

发明人： Mi RYU ,  In Pyo HONG ,  Bong Ki KIM ,  Seok Hyun PARK ,  Joon Hyun PARK

IPC分类号： C12N9/88 ,  C12N15/77 ,  C12P13/08

CPC分类号： C12N9/88 ,  C12N15/77 ,  C12P13/08 ,  C12Y402/01011

摘要： The present invention relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The Corynebacterium glutamicum mutant strain is able to produce L-lysine in an improved yield as a result of increasing the supply of the L-lysine precursor and sugar utilization by increasing or enhancing the expression of the gene encoding enolase and/or reducing or weakening the expression of the gluconate operon transcriptional repressor.

公开(公告)号：US20240175064A1

公开(公告)日：2024-05-30

申请号：US18280629

申请日：2021-04-26

申请人： DAESANG CORPORATION

发明人： Ha Eun KIM ,  Sun Hee LEE ,  Young Ju LEE ,  Seok Hyun PARK ,  Joon Hyun PARK

IPC分类号： C12P13/08 ,  C12N1/20 ,  C12N9/02 ,  C12N15/77 ,  C12R1/15

CPC分类号： C12P13/08 ,  C12N1/20 ,  C12N9/0008 ,  C12N15/77 ,  C12R2001/15 ,  C12Y102/01011

摘要： The present disclosure relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The mutant strain may produce L-lysine in an improved yield compared to the parent strain by increasing or enhancing the expression of a gene encoding aspartate-semialdehyde dehydrogenase therein.

公开(公告)号：US20240026283A1

公开(公告)日：2024-01-25

申请号：US17937833

申请日：2022-10-04

申请人： DAESANG CORPORATION

发明人： Mi RYU ,  Sun Jun YOON ,  In Pyo HONG ,  Seok Hyun PARK

IPC分类号： C12N1/20

CPC分类号： C12N1/205 ,  C12R2001/15

摘要： The present disclosure relates to a Corynebacterium sp. mutant strain having increased L-arginine or L-citrulline productivity and a method of producing L-arginine or L-citrulline using the same. The Corynebacterium sp. mutant strain has enhanced activity of acetylornithine aminotransferase involved in the L-arginine biosynthesis pathway, and thus is capable of producing L-arginine or L-citrulline productivity in an increased yield compared to a parent strain.

公开(公告)号：US20230332192A1

公开(公告)日：2023-10-19

申请号：US18025056

申请日：2021-03-23

申请人： DAESANG CORPORATION

发明人： Dong Seok LEE ,  Min Jin CHOI ,  Moon Jeong KIM ,  Seok Hyun PARK ,  Jae Chun HAN

IPC分类号： C12N15/77 ,  C12P13/10 ,  C12N1/20

CPC分类号： C12P13/10 ,  C12N1/20 ,  C12N15/77 ,  C12R2001/15

摘要： The present invention relates to a Corynebacterium glutamicum mutant strain having increased L-citrulline productivity and a method of producing L-citrulline using the same. The Corynebacterium glutamicum mutant strain is capable of producing L-citrulline in high yield and high concentration because the activity of the transport protein that is expressed by the NCgl2816 gene therein has been weakened or inactivated.