公开(公告)号：US20250026949A1

公开(公告)日：2025-01-23

申请号：US18891406

申请日：2024-09-20

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Masahiro HIGASHI ,  Kanako NAKANISHI ,  Sumi ISHIHARA ,  Tomohito HAMADA ,  Kensuke YAMATO ,  Kazuki KANEKO ,  Yosuke KISHIKAWA

IPC: C09D129/10 ,  C08F214/22 ,  C08F216/14 ,  C09D127/16

Abstract: Provided is a fluoropolymer containing a polymerization unit (I) derived from a monomer (I) represented by the general formula (I) and a polymerization unit (II) derived from a monomer (II) represented by the formula (II): CX1X3═CX2R(—CZ1Z2-A0)m  (I) wherein X1 and X3 are each independently F, Cl, H, or CF3; X2 is H, F, an alkyl group, or a fluorine-containing alkyl group; A0 is an anionic group; R is a linking group; Z1 and Z2 are each independently H, F, an alkyl group, or a fluorine-containing alkyl group; and m is an integer of 1 or more; and CHF═CHF  (II)

公开(公告)号：US20220008450A1

公开(公告)日：2022-01-13

申请号：US17281810

申请日：2019-09-27

Applicant: DAIKIN INDUSTRIES, LTD. ,  KAGOSHIMA UNIVERSITY

Inventor： Tomohito HAMADA ,  Yosuke KISHIKAWA ,  Kanako INOO ,  Masanori IKEDA ,  Midori TAKEDA

IPC: A61K31/7076 ,  A61P31/20

Abstract: The present disclosure provides an anti-hepatitis B virus agent and a prophylactic or therapeutic agent for hepatitis B virus-related diseases, each comprising a nucleic acid analogue as an active ingredient. The problem can be solved by 2′-deoxy-2′-fluoro-β-2-fluoro-D-adenosine or its prodrug, or a pharmaceutically acceptable salt thereof, or a solvate thereof.

公开(公告)号：US20220033432A1

公开(公告)日：2022-02-03

申请号：US17473635

申请日：2021-09-13

Applicant: DAIKIN INDUSTRIES, LTD. ,  KAGOSHIMA UNIVERSITY

Inventor： Tomohito HAMADA ,  Hideyuki IKEUCHI ,  Kanako INOO ,  Yosuke KISHIKAWA ,  Masanori IKEDA ,  Midori TAKEDA

IPC: C07H19/16 ,  A61K31/7076 ,  A61P1/16 ,  A61P35/00 ,  A61P31/20

Abstract: The present disclosure aims to provide an anti-hepatitis B virus agent, and a prophylactic or therapeutic agent for a hepatitis B virus-related disease, each comprising a nucleic acid analogue as an active ingredient.
The above object can be attained by an anti-hepatitis B virus agent, or a prophylactic or therapeutic agent for a hepatitis B virus-related disease, each comprising, as an active ingredient, a compound represented by the following formula (1): wherein R is a halogen atom, an amino group, a methoxy group, or a cyano group, or its prodrug, or a pharmaceutically acceptable salt thereof, or a solvate thereof.

公开(公告)号：US20180327342A1

公开(公告)日：2018-11-15

申请号：US15777494

申请日：2016-11-22

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Michiaki OKADA ,  Akinori YAMAMOTO ,  Yosuke KISHIKAWA

IPC: C07C29/48 ,  B01J27/13 ,  C07C31/42

CPC classification number: C07C29/48 ,  B01J27/13 ,  C07B61/00 ,  C07C31/42 ,  C07C253/30 ,  C07C255/12

Abstract: The present invention provides a method for producing a diol having a specific structure in high yields while keeping high selectivity. Provided is a method for producing a diol having a specific structure by oxidizing an olefin having a specific structure in the presence of a ruthenium compound.

公开(公告)号：US20230404065A1

公开(公告)日：2023-12-21

申请号：US18240635

申请日：2023-08-31

Applicant: The University of Tokyo ,  DAIKIN INDUSTRIES, LTD.

Inventor： Taichi ITO ,  Arvind Kumar Singh CHANDEL ,  Tomohito HAMADA ,  Shigehito SAGISAKA ,  Yosuke KISHIKAWA

IPC: A01N1/02 ,  B01J13/12

CPC classification number: A01N1/0231 ,  A01N1/0226 ,  B01J13/12

Abstract: A core-shell microparticle includes a shell containing at least one polymer selected from the group consisting of fluorine-containing polymers, fluorine-free vinyl polymers, and silicone polymers, and a core containing a fluorocarbon.

公开(公告)号：US20200283370A1

公开(公告)日：2020-09-10

申请号：US16881997

申请日：2020-05-22

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Michiaki OKADA ,  Akiyoshi YAMAUCHI ,  Yosuke KISHIKAWA

IPC: C07C68/02 ,  C07C69/96

Abstract: A method for producing an asymmetric chain carbonate by reacting an alcohol with a halocarbonate ester compound in the presence of a basic magnesium salt.

公开(公告)号：US20210032472A1

公开(公告)日：2021-02-04

申请号：US16965738

申请日：2019-01-31

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Yosuke KISHIKAWA ,  Masamichi SUKEGAWA

IPC: C09B11/24 ,  G01N21/78 ,  G01N33/52

Abstract: A main object of the present invention is to provide a novel acetylpolyamine detection agent that is easy to produce and use. This object is achieved by an acetylpolyamine detection agent comprising compound (A) having one or more polyether rings, wherein the polyether rings have one or more hydroxyl groups as substituents.

公开(公告)号：US20180346404A1

公开(公告)日：2018-12-06

申请号：US15774829

申请日：2016-11-22

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Michiaki OKADA ,  Akiyoshi YAMAUCHI ,  Yosuke KISHIKAWA

IPC: C07C68/02

Abstract: A method for producing an asymmetric chain carbonate by reacting an alcohol with a halocarbonate ester compound in the presence of a basic magnesium salt.

公开(公告)号：US20180099922A1

公开(公告)日：2018-04-12

申请号：US15564927

申请日：2016-04-08

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Makoto MATSUURA ,  Asako YOSHIYAMA ,  Akihiro GOTOU ,  Manaho MIYAZAKI ,  Yosuke KISHIKAWA

IPC: C07C69/653 ,  C07C67/62

CPC classification number: C07C69/653 ,  C07C47/02 ,  C07C67/62

Abstract: An object of the present invention is to provide a method for stabilizing an acrylic acid derivative, and a composition containing an acrylic acid derivative in which the acrylic acid derivative is stabilized. The present invention provides a composition comprising: (A) an acrylic acid derivative represented by Formula (I): (wherein Ra represents alkyl, fluoroalkyl, aryl that may have one or more substituents, or hydrogen; and X represents fluorine, alkyl, perfluoroalkyl, or hydrogen); and (B) aldehyde, wherein the content of acrylic acid derivative (A) is 30% (w/w) or more.

公开(公告)号：US20180093940A1

公开(公告)日：2018-04-05

申请号：US15564926

申请日：2016-04-08

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Tomohito HAMADA ,  Yosuke KISHIKAWA ,  Makoto MATSUURA ,  Asako YOSHIYAMA

IPC: C07C69/653 ,  C07C67/62

CPC classification number: C07C69/653 ,  C07C31/02 ,  C07C67/62

Abstract: An object of the present invention is to provide a method for stabilizing an acrylic acid derivative, and a composition containing an acrylic acid derivative in which the acrylic acid derivative is stabilized. The present invention provides a composition comprising: (A) an acrylic acid derivative represented by Formula (I): (wherein R1 and R2 are the same or different, and each represents alkyl, fluoroalkyl, aryl that may have one or more substituents, halogen, or hydrogen; R3 represents alkyl, fluoroalkyl, aryl that may have one or more substituents, or hydrogen; and X represents fluoroalkyl, alkyl, halogen, or hydrogen); and (B) alcohol, wherein the content of acrylic acid derivative (A) is 30% (w/w) or more.